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当前位置: 首页 > 产品中心 > Other_recombinant_protein > Adipogen/Angiopoietin-2 (human) (rec.)/AG-40B-0114-3010/3 x 10 µg
商品详细Adipogen/Angiopoietin-2 (human) (rec.)/AG-40B-0114-3010/3 x 10 µg
Adipogen/Angiopoietin-2 (human) (rec.)/AG-40B-0114-3010/3 x 10 µg
Adipogen/Angiopoietin-2 (human) (rec.)/AG-40B-0114-3010/3 x 10 µg
商品编号: AG-40B-0114-3010
品牌: Adipogen Inc
市场价: ¥8000.00
美元价: 4800.00
产地: 美国(厂家直采)
公司:
产品分类: 其它重组蛋白
公司分类: Other_recombinant_protein
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
MoreInformation
ProductDetails
SynonymsAng-2;Ang2;Angpt2
ProductTypeProtein
Properties
Source/HostHEK293cells
SequenceHumanangiopoietin-2(aa19-496)isfusedattheN-terminustoaFLAG®-tag.
CrossreactivityHuman
Mouse
SpecificityBindstothehumanandmouseTie-2receptor.
MW~70kDa(SDS-PAGE)
Purity≥95%(SDS-PAGE)
EndotoxinContent<0.01eu mu;g="" purified="" protein="" (lal="" test;="" lonza).="">
Concentration0.1mg/mlafterreconstitution.
ReconstitutionReconstitutewith100μlsterilewater.
FormulationLyophilized.ContainsPBSwithtrehaloseandBrij35.
OtherProductDataUniProtlinkO15123:Angiopoietin-2(human)
FLAGisaregisteredtrademarkofSigma-AldrichCo.
ShippingandHandling
ShippingBLUEICE
ShortTermStorage+4°C
LongTermStorage-20°C
HandlingAdviceAfterreconstitution,preparealiquotsandstoreat-20°C.
Avoidfreeze/thawcycles.
PBScontainingatleast0.1%BSAshouldbeusedforfurtherdilutions.
Use/StABIlityStableforatleast6monthsafterreceiptwhenstoredat-20°C.
Documents
MSDSDownloadPDF
ProductSpecificationSheet
DatasheetDownloadPDF
Angiopoietin-1(Ang-1)andAngiopoietin-2(Ang-2)arecloselyrelatedsecretedligandswhichbindwithsimilaraffinitytoTie-2.Tie-2andangiopoietinshavebeenshowntoplaycriticalrolesinembryogenicangiogenesisandinmaintainingtheintegrityoftheadultvasculature.Ang-1activatesTie-2signalingonendothelialcellstopromotechemotaxis,cellsurvival,cellsprouting,vesselgrowthandstabilization.Ang-2hasbeenidentifiedasasecretedproteinligandofTie-2andhasalternativelybeenreportedtobeanantagoNISTforAng-1inducedTie-2signalingaswellasanagonistforTie-2signaling,dependingonthecellcontext.
ProductReferences
  1. InteractionbetweenTiereceptorsmodulatesangiogenicactivityofangiopoietin2inendothelialProgenitorcells:K.L.Kim,etal.;Cardiovasc.Res.72,394(2006)
  2. Twonaturaleudesmane-typesesquiterpenesfromLaggeraalatainhibitangiogenesisandsuppressbreastcancercellmigrationthroughVEGF-andAngiopoietin2-mediatedsignalingpathways: N.Liang,etal.;Int.J.Oncol.51,213(2017)
品牌介绍
Adipogen公司由三个子公司组成,分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国,运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发,如癌症、免疫、炎症、代谢疾病(糖尿病、肥胖)、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外,也可提供抗体和蛋白产品,Adipogen拥有自己的化学实验室,致力于开发创新型小分子化合物。