脂肪原/20S蛋白酶体（兔）/AG-40T-0209-C050/50µg
商品编号：
AG-40T-0209-C050
品牌：
Adipogen Inc
市场价：
¥4720.00
美元价：
2832.00
产品分类：
其它重组蛋白
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| ProductDetails | |
|---|---|
| ProductType | Protein |
| Properties | |
| Source/Host | RabbitErythrocytes |
| Sequence | Rabbit20SProteasome. |
| Crossreactivity | Rabbit |
| Formulation | Liquid.InHEPES,NaClandDTT. |
| OtherProductData | Use:AbletodegradesubstratesinanATP-independentmanner.ItcanbeactivatedchemicallywithSDS(0.035%)orbytheadditionofPA28.Reactionconditionswillneedtobeoptimizedforeachspecificapplication.Werecommendaninitialproteinconcentrationof0.5-5nM. |
| Declaration | ManufacturedbyBostonBiochem |
| ShippingandHandling | |
| Shipping | DRYICE |
| ShortTermStorage | -20°C |
| LongTermStorage | -80°C |
| HandlingAdvice | Aliquottoavoidfreeze/thawcycles. |
| Use/StABIlity | Stableforatleast1yearafterreceiptwhenstoredat-80°C. |
| Documents | |
| MSDS | No |
| ProductSpecificationSheet | |
| Datasheet |  DownloadPDF |
The20SProteasomeisthecatalyticcorecomponentofthemulti-complex26SProteasomethatselectivelydegradesintracellularproteins.Itiscommonlyassociatedwithregulatorycomplexes,whichincludethe19SProteasome,thePA28α/βcomplex,orthePA28γcomplex.The20SProteasomeiscomposedof28subunitsarrangedintofourstackedrings.Theouterrings,containingsevensubunitseach,arecomposedofclosely-relatedbutnon-identicalαsubunits.Theamino-terminaltailsoftheαsubunitsformagatethatrestrictssubstrateentryintothecatalyticcore.Theinnerrings,alsocontainingsevensubunitseach,arecomposedofclosely-relatedbutnon-identicalβsubunits.Theamino-terminaltailsofsixoftheβsubunits,threeperring,haveproteolyticactivity.Inhibitionof20SProteasomeproteolyticcoreactivityusingsmallmoleculeinhibitorsisavaluabletoolforthefunctionalstudyofavarietyofproteinsandfortherapeuticintervention.The20SProteasomecanbeactivatedchemicallybytheadditionofdetergentorbytheproteinaceousactivatorPA28activatorα.
品牌介绍
Adipogen公司由三个子公司组成，分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国，运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发，如癌症、免疫、炎症、代谢疾病（糖尿病、肥胖）、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外，也可提供抗体和蛋白产品，Adipogen拥有自己的化学实验室，致力于开发创新型小分子化合物。
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