Adipogen/Pseudolaric acid B/AG-CN2-0083-M001/1 mg
商品编号：
AG-CN2-0083-M001
品牌：
Adipogen Inc
市场价：
¥1900.00
美元价：
1140.00
产品分类：
其他试剂
公司分类：
Other_reagents
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| ProductDetails | |
|---|---|
| Synonyms | PseudolarixacidB;PLAB;PAB |
| ProductType | Chemical |
| Properties | |
| Formula | C23H28O8 |
| MW | 432.5 |
| CAS | 82508-31-4 |
| RTECS | KJ4620000 |
| Source/HostChemicals | IsolatedfromPseudolarixkaempferi. |
| PurityChemicals | ≥98%(HPLC) |
| Appearance | Whitetooff-whitesolid. |
| Solubility | SolubleinDMSO,ethanol,methanolorchloroform. |
| InChiKey | VDGOFNMYZYBUDT-YDRCMHEVSA-N |
| ShippingandHandling | |
| Shipping | AMBIENT |
| ShortTermStorage | +4°C |
| LongTermStorage | +4°C |
| HandlingAdvice | Keepcoolanddry. |
| Use/StABIlity | Stableforatleast2yearsafterreceiptwhenstoredat+4°C. |
| Documents | |
| MSDS |  DownloadPDF |
| ProductSpecificationSheet | |
| Datasheet | DownloadPDF |
- Antifungalandantifertilitycompound[1,3].
- Antitumorcompound[2,7-9,13].
- PPARαsignalingagoNIST[4].
- Angiogenesisinhibitor[5,6,11].
- Apoptosisandautophagyinducer[7,9,15,17].
- Microtubule-destabilizingagent[8,11].
- Anti-inflammatory.InhibitsNF-κBandp38signaling[12,14].
- Immunosuppressive[16].
ProductReferences
- PseudolaricAcidsfromPseudolarixkaempferi:B.N.Zhou,etal.;PlantaMed.47,35(1983)
- ThecytotoxicprinciplesofPseudolarixkaempferi:pseudolaricacid-Aand-Bandrelatedderivatives:D.J.Pan,etal.;PlantaMed.56,383(1990)
- AntifungalevaluationofpseudolaricacidB,amajorconstituentofPseudolarixkaempferi:E.Li,etal.;J.Nat.Prod.58,57(1995)
- Pseudolaricacidanalogsasanewclassofperoxisomeproliferator-activatedreceptoragonists:M.S.Jardat,etal.;PlantaMed.68,667(2002)
- PseudolarixacidBinhibitsangiogenesisbyantagonizingthevascularendothelialgrowthfactor-mediatedanti-apoptoticeffect:W.F.Tan,etal.;Eur.J.Pharmacol.499,219(2004)
- PseudolaricacidBinhibitsangiogenesisandreduceshypoxia-inducIBLefactor1alphabypromotingproteasome-mediateddegradation:M.H.Li,etal.;Clin.CancerRes.10,8266(2004)
- PseudolaricacidBinducesapoptosisthroughp53andBax/Bcl-2pathwaysinhumanmelanomaA375-S2cells:X.F.Gong,etal.;Arch.Pharm.Res.28,68(2005)
- PseudolaricacidB,anovelmicrotubule-destabilizingagentthatcircumventsmultidrugresistancephenotypeandexhibitsantitumoractivityinvivo:V.K.Wong,etal.;Clin.CancerRes.11,6002(2005)
- EffectofpseudolaricacidBongastriccancercells:inhibitionofproliferationandinductionofapoptosis:K.S.Li,etal.;WorldJ.Gastroenterol.11,7555(2005)
- PseudolarixacidB,anewtubulin-bindingagent,inhibitsangiogenesisbyinteractingwithanovelbindingsiteontubulin:Y.G.Tong,etal.;Mol.Pharmacol.69,1226(2006)
- InvolvementofJNK-initiatedp53accumulationandphosphorylationofp53inpseudolaricacidBinducedcelldeath:X.Gong,etal.;Exp.Mol.Med.38,428(2006)
- PseudolaricacidBsuppressesTlymphocyteactivationthroughinhibitionofNF-kappaBsignalingpathwayandp38phosphorylation:T.Li,etal.; J.CellBiochem.108,87(2009)
- SelectiveinhibitionofhumanleukemiacellgrowthandinductionofcellcyclearrestandapoptosisbypseudolaricacidB:G.Ma,etal.;J.CancerRes.Clin.Oncol.136,1333(2010)
- PseudolaricacidBinhibitsinduciblecyclooxygenase-2expressionviadownregulationoftheNF-κBpathwayinHT-29cells:L.Hou,etal.;J.CancerRes.Clin.Oncol.138,885(2012)
- PseudolaricacidBinducesapoptosisviaproteasome-mediatedBcl-2degradationinhormone-refractoryprostatecancerDU145cells:D.Zhao,etal.;Toxicol.InVitro26,595(2012)
- TheImmunosuppressiveActivityofPseudolaricAcidBonTlymphocytesinvitro:N.Wei,etal:Phytother.Res.27,980(2013)
- PseudolaricAcidBInducesCaspase-DependentApoptosisandAutophagicCellDeathinProstateCancerCells:J.Tong,etal.;Phytother.Res.27,885(2013)
品牌介绍
Adipogen公司由三个子公司组成，分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国，运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发，如癌症、免疫、炎症、代谢疾病（糖尿病、肥胖）、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外，也可提供抗体和蛋白产品，Adipogen拥有自己的化学实验室，致力于开发创新型小分子化合物。
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