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当前位置: 首页 > 产品中心 > Other_reagents > 脂肪原/赛马普林A/AG-CN2-0088-C500/500µg
商品详细脂肪原/赛马普林A/AG-CN2-0088-C500/500µg
脂肪原/赛马普林A/AG-CN2-0088-C500/500µg
脂肪原/赛马普林A/AG-CN2-0088-C500/500µg
商品编号: AG-CN2-0088-C500
品牌: Adipogen Inc
市场价: ¥5400.00
美元价: 3240.00
产地: 美国(厂家直采)
公司:
产品分类: 其他试剂
公司分类: Other_reagents
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
More Information
Product Details
Synonyms Bisprasin; NSC-614495
Product Type Chemical
Properties
Formula C22H24Br2N4O6S2
MW 664.4
CAS 110659-91-1
Source/Host Chemicals Isolated from Psammaplysilla purpurea.
Purity Chemicals ≥98% (HPLC)
Appearance Off-white solid.
Solubility Soluble in DMSO, MeOH/H2O(40:60) or CH3CN/H2O(40:60). Insoluble in water.
InChi Key LMAFSGDNHVBIHU-HJTNQMAYSA-N
Shipping and Handling
Shipping AMBIENT
Short Term Storage +4°C
Long Term Storage -20°C
Handling Advice Keep cool and dry.
Use/Stability Stable for at least 2 years after receipt when stored at -20°C.
Documents
MSDS Download PDF
Product Specification Sheet
Datasheet Download PDF
  • Antibiotic [1].
  • Caffeine-like Ca2+ releaser in heavy sarcoplasmic reticulum (HSR) [2].
  • Antifungal [3].
  • Chitinase inhibitor [3].
  • DNA methyltransferase inhibitor [4].
  • Histone deacetylase (HDAC) inhibitor [4, 5].
  • Anticancer compound. Angiogenesis suppressor [5].
Product References
  1. Psammaplin A, a natural bromotyrosine derivative from a sponge, possesses the antibacterial activity against methicillin-resistant Staphylococcus aureus and the DNA gyrase-inhibitory activity: D. Kim, et al.; Arch. Pharm. Res. 22, 25 (1999)
  2. Bisprasin, a novel Ca(2+) releaser with caffeine-like properties from a marine sponge, Dysidea spp., acts on Ca(2+)-induced Ca(2+) release channels of skeletal muscle sarcoplasmic reticulum: A. Suzuki, et al.; J. Pharmacol. Exp. Ther. 292, 725 (2000)
  3. Psammaplin A, a chitinase inhibitor isolated from the Fijian marine sponge Aplysinella rhax: J.N. Tabudravu, et al.; Bioorg. Med. Chem. 10, 1123 (2002)
  4. Psammaplins from the sponge Pseudoceratina purpurea: inhibition of both histone deacetylase and DNA methyltransferase: I.C. Pina, et al.; J. Org. Chem. 68, 3866 (2003)
  5. Psammaplin A, a marine natural product, inhibits aminopeptidase N and suppresses angiogenesis in vitro: J.S. Shim, et al.; Cancer Lett. 203, 163 (2004)
  6. Psammaplin A is a natural prodrug that inhibits class I histone deacetylase: D.H. Kim, et al.; Exp. Mol. Med. 39, 47 (2007)
  7. Defining the mechanism of action and enzymatic selectivity of psammaplin A against its epigenetic targets: M.B. Baud, et al.; J. Med. Chem. 55, 1731 (2012)
品牌介绍
Adipogen公司由三个子公司组成,分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国,运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发,如癌症、免疫、炎症、代谢疾病(糖尿病、肥胖)、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外,也可提供抗体和蛋白产品,Adipogen拥有自己的化学实验室,致力于开发创新型小分子化合物。