Adipogen/Prodigiosin/AG-CN2-0105-M001/1 mg
商品编号：
AG-CN2-0105-M001
品牌：
Adipogen Inc
市场价：
¥4200.00
美元价：
2520.00
产品分类：
其他试剂
公司分类：
Other_reagents
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| ProductDetails | |
|---|---|
| Synonyms | NSC47147;BRN4526727 |
| ProductType | Chemical |
| Properties | |
| Formula | C20H25N3O |
| MW | 323.4 |
| MerckIndex | 14:7767 |
| CAS | 82-89-3 |
| Source/HostChemicals | Isolatedfromγ-proteobacteriumstrainMS-02-063. |
| PurityChemicals | ≥95%(HPLC) |
| Appearance | Darkredsolid. |
| Solubility | Solubleinmethanol,ethanol,chloroform,ethylacetate,hexane,acetoneoracetonitrile.Insolubleinwater. |
| Declaration | ManufacturedbyBiOlinksK.K.withcourtesystrainfromTheKitasatoInstitute. |
| InChiKey | SZXDNGVQRDTJSD-FOWTUZBSSA-N |
| ShippingandHandling | |
| Shipping | AMBIENT |
| ShortTermStorage | +4°C |
| LongTermStorage | -20°C |
| HandlingAdvice | Protectfromlight. |
| Use/StABIlity | Stableforatleast3yearsafterreceiptwhenstoredat-20°C. |
| Documents | |
| MSDS |  DownloadPDF |
| ProductSpecificationSheet | |
| Datasheet | DownloadPDF |
- Red-pigmentedantibiotic[1].
- Antimalarial[2,13].
- Immunosuppressive[3,7,11,12].
- Apoptosisinducer[4-6,15].
- Cytotoxic.Inducesphosphorylationofp38-MAPK[8].
- Antimetastatic.Tumorinvasioninhibitor[9].
- Inducesp21WAF1/CIP1expression[10].
- Anticancercompound[11,12,15].
- gp91(phox)andiNOSexpressioninhibitor[14].
- mTORC1andmTORC2complexinhibitor[16].
- Down-regulatesSKP2toinducep27(KIP1)stabilization[17].
ProductReferences
- TheAntibioticActivityofViolacein,Prodigiosin,andPhthiocol:H.C.Lichstein&V.F.VanDeSand;J.Bacteriol.52,145(1946)
- Antimalarialactivityofprodigiosin:A.J.Castro;Nature213,903(1967)
- T-cellspecificimmunosuppressionbyprodigiosinisolatedfromSerratiamarcescens:S.B.Han,etal.;Int.J.Immunopharmacol.20,1(1998)
- ProdigiosinfromthesupernatantofSerratiamarcescensinducesapoptosisinhaematopoieticcancercelllines:B.Montaner,etal.;Br.J.Pharmacol.131,585(2000)
- Prodigiosin-inducedapoptosisinhumancoloncancercells:B.Montaner&R.Perez-Tomas;LifeSci.68,2025(2001)
- ProdigiosininducescelldeathandmorphologicalchangesindicativeofapoptosisingastriccancercelllineHGT-1:C.Diaz-Ruiz,etal.;Histol.Histopathol.16,415(2001)
- ProdigiosinblocksTcellactivationbyinhibitinginterleukin-2Ralphaexpressionanddelaysprogressionofautoimmunediabetesandcollagen-inducedarthritis:S.B.Han,etal.;JPET299,415(2001)
- Thecytotoxicprodigiosininducesphosphorylationofp38-MAPKbutnotofSAPK/JNK:B.Montaner&R.Perez-Tomas;Toxicol.Lett.129,93(2002)
- Antimetastaticeffectofprodigiosinthroughinhibitionoftumorinvasion:J.Zhang,etal.;Biochem.Pharmacol.69,407(2005)
- Theanticanceragentprodigiosininducesp21WAF1/CIP1expressionviatransforminggrowthfactor-betareceptorpathway:V.Soto-Cerrato,etal.;Biochem.Pharmacol.74,1340(2007)
- Prodigiosinsasanticanceragents:livinguptotheirname:R.Pandey,etal.;Curr.Pharm.Des.15,732(2009)
- Newinsightsontheantitumoralpropertiesofprodiginines:R.Perez-Tomas&M.Vinas;Curr.Med.Chem.17,2222(2010)
- ProdigiosinproducedbySerratiamarcescensNMCC46asamosquitolarvicidalagentagainstAedesaegyptiandAnophelesstephensi:C.D.Patil,etal.;Parasitol.Res.109,1179(2011)
- Prodigiosininhibitsgp91(phox)andiNOSexpressiontoprotectmiceagainsttheoxidative/nitrosativebraininjuryinducedbyhypoxia-ischemia:C.C.Chang,etal.;Toxicol.Appl.Pharmacol.257,137(2011)
- Prodigiosin,theredpigmentofSerratiamarcescens,showscytotoxiceffectsandapoptosisinductioninHT-29andT47Dcancercelllines:D.Dalili,etal;Nat.Prod.Res.(Epubaheadofprint)(2011)
- IdentificationofdualmTORC1andmTORC2inhibitorsinmelanomacells:prodigiosinvs.obatoclax:M.Espona-Fiedler,etal.;Biochem.Pharmacol.83,489(2012)
- Prodigiosindown-regulatesSKP2toinducep27(KIP1)stabilizationandantiproliferationinhumanlungadenocarcinomacells:H.Y.Hsieh,etal.;Br.J.Pharmacol.166,2095 (2012)
品牌介绍
Adipogen公司由三个子公司组成，分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国，运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发，如癌症、免疫、炎症、代谢疾病（糖尿病、肥胖）、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外，也可提供抗体和蛋白产品，Adipogen拥有自己的化学实验室，致力于开发创新型小分子化合物。
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