脂肪原/TR1（人）ELISA试剂盒（10x96T）/YIF-LF-EK0124/10 x 96孔
商品编号：
YIF-LF-EK0124
品牌：
Adipogen Inc
市场价：
¥96100.00
美元价：
57660.00
产品分类：
夹心法ELISA
公司分类：
Sandwich_method_ELISA
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| ProductDetails | |
|---|---|
| Synonyms | TR;TXNRD1;GRIM12;GRIM-12;EC=1.8.1.9;ThioredoxinReductaseTR1;KM-102-derivedReductase-likeFactor;ThioredoxinReductase1;Cytoplasmic;GeneAssociatedwithRetinoicandIFN-inducedMortality12Protein |
| ProductType | Kit |
| Properties | |
| ApplicationSet | CompoundScreening |
| Crossreactivity | Human |
| Quantity | 10x96wells |
| Sensitivity | 0.39ng/ml |
| AssayType | Sandwich |
| OtherProductData | ClickhereforOriginalManufacturerProductDatasheet Ourproductdescriptionmaydifferslightlyfromtheoriginalmanufacturersproductdatasheet. |
| Declaration | ManufacturedbyAbFrontier |
| ShippingandHandling | |
| Shipping | BLUEICE |
| ShortTermStorage | +4°C |
| LongTermStorage | +4°C |
| HandlingAdvice | Anyunusedreconstitutedstandardshouldbediscardedorfrozenat-80℃. Standardcanbefrozenandthawedonetimeonlywithoutlossofimmunoreactivity. |
| Documents | |
| Manual |  DownloadPDF |
| MSDS | No |
| ProductSpecificationSheet | |
| Datasheet | DownloadPDF |
Themammalianthioredoxinreductases(TrxRs)areafamilyofselenocysteine-containingpyridinenucleotide-disulfideoxidoreductases.AllthemammalianTrxRsarehomologoustoglutathionereductasewithrespecttoprimarystructureincludingtheconservedredoxcatalyticsite(-Cys-Val-Asn-Val-Gly-Cys-)butdistinctivelywithaC-terminalextensioncontainingacatalyticallyactivepenultimateselenocysteine(SeCys)residueintheconservedsequence(-Gly-Cys-SeCys-Gly).TrxRishomodimericproteininwhicheachmonomerincludesanFADprostheticgroup,aNADPHbindingsiteandaredoxcatalyticsite.ElectronsaretransferredfromNADPHviaFADandtheactive-sitedisulfidetoC-terminalSeCys-containingredoxcenter,whichthenreducesthesubstratelikethioredoxin.ThemembersofTrxRfamilyare55-58kilodaltoninmolecularsizeandcomposedofthreeisoformsincludingcytosolicTrxR1,mitochondrialTrxR2,andTrxR3,knownasTrxandGSSGreductase(TGR).TrxRplaysakeyroleinprotectionofcellsagainstoxidativestressandredox-regulatorymechanismoftranscriptionfactorsandvariousBIOLOGicalphenomena(1).Isoform1maypossessglutaredoxinactivityaswellasthioredoxinreductaseactivityandinducesactinandtubulinpolymerization,leADIngtoformationofcellmembraneprotrusions.Isoform4enhancesthetranscriptionalactivityofestrogenreceptorsαandβwhileisoform5enhancesthetranscriptionalactivityoftheβreceptoronly.Isoform5alsomediatescelldeathinducedbyacombinationofinterferon-βandretinoicacid.
品牌介绍
Adipogen公司由三个子公司组成，分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国，运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发，如癌症、免疫、炎症、代谢疾病（糖尿病、肥胖）、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外，也可提供抗体和蛋白产品，Adipogen拥有自己的化学实验室，致力于开发创新型小分子化合物。
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