脂肪原/RBP4(人)ELISA试剂盒(定量)/AG-45A-0035YTP-KI01/2 x 96孔
商品编号:
AG-45A-0035YTP-KI01
品牌:
Adipogen Inc
市场价:
¥17400.00
美元价:
10440.00
产品分类:
夹心法ELISA
公司分类:
Sandwich_method_ELISA
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
| ProductDetails | |
|---|---|
| Synonyms | RetinolBindingProtein4 |
| ProductType | Kit |
| Properties | |
| ApplicationSet | QuantitativeELISA |
| Specificity | DetectshumanRBP4.Doesnotcross-reactwithmouseRBP4,ratRBP4,humanADIponectin,humanresistin,humanvaspin,humanleptinorhumanNampt. |
| Crossreactivity | Human |
| Quantity | 1x96wells |
| Sensitivity | 380pg/ml |
| Range | 0.39to25ng/ml |
| SampleType | CellCultureSupernatant Plasma Serum Urine |
| AssayType | Sandwich |
| DetectionType | Colorimetric |
| ShippingandHandling | |
| Shipping | BLUEICE |
| ShortTermStorage | +4°C |
| LongTermStorage | +4°C |
| HandlingAdvice | Afterstandardreconstitution,preparealiquotsandstoreat-20°C. Avoidfreeze/thawcycles. Plateandreagentsshouldreachroomtemperaturebeforeuse. |
| Use/StABIlity | 12monthsafterthedayofmanufacturing.SeeexpirydateonELISAKitbox. |
| Documents | |
| Manual | DownloadPDF |
| MSDS | DownloadPDF |
| ProductSpecificationSheet | |
| Datasheet | DownloadPDF |
Retinolbindingprotein4(RBP4;RBP)isa21kDasecretedprotein,amemberofthelipocalinfamilyandisknownastheprimarytransporterofretinol(vitaminA)totissues.ArecentreportrevealedRBP4asanadipokinelinkingglucosetransporter4(GLUT4)suppressioninadiposetissuetoinsulin.ElevatedhumanandmouseserumRBP4levelsareassociatedwithinsulinresistanceanditsseverity,obesityandcertaincomponentsofmetabolicsyndrome.FurThermore,humanserumRBP4levelsarecloselyrelatedtorenalfunctionandrecentstudieshaveshownanassociationbetweenserumRBP4levelsandurinaryalbuminexcretion.TheurinaryRBP4concentrationmaybeavaluableMarkerforboth,insulinresistanceandmicroalbuminuriaininsulin-resistantsubjects.
ProductReferences
- Twopatternsofadipokineandotherbiomarkerdynamicsinalong-termweightlossintervention:M.Blueher,etal.;DiabetesCare35,342(2012)
- Thenormoglycemicfirst-degreerelativesofpatientswithtype2diabetesmellitushavelowcirculatingomentin-1andadiponectinlevels:S.Akbarzadeh,etal.;Cytokine58,295(2012)
- Increasedplasmalevelsofretinol-bindingprotein4withvisceralobesityisassociatedwithcardiovascularriskfactors:J.C.Won,etal.;J.Diabet.Invest.3,457(2012)
- Theassociationofcarotidintimamediathicknesswithretinolbindingprotein-4andtotalandhighmolecularweightadiponectinintype2diabeticpatients:M.Mansouri,etal.;J.Diabet.Metab.Dis.11,2(2012)
- EffectsofaCombinedAerobicandResistanceExerciseProgramonC1q/TNF-RelatedProtein-3(Ctrp-3)andCTRP-5Levels:H.Y.Choi,etal.;DiabetesCare36,3321(2013)
- Associationsbetweentissuevisfatin/nicotinamide,phosphoribosyltransferase(Nampt),retinolbindingprotein-4,andvaspinconcentrationsandinsulinresistanceinmorbidlyobesesubjects:Z.Goktas,etal.;MediatorsInflamm.2013,861496(2013)
- Lackofrelationshipbetweencordserumangiopoietin-likeprotein4(ANGPTL4)andlipolyticactivityinhumanneonatesbornbyspontaneousdelivery:H.Ortega-Senovilla,etal.;PLoSOne8,e81201(2013)
- Associationsofretinol-bindingprotein4withoxidativestress,inflammatorymarkers,andmetabolicsyndromeinamiddle-agedandelderlyChinesepopulation:Y.Liu,etal.;Diabetol.Metab.Syndr.6,25(2014)
- Identificationofadipokineclustersrelatedtoparametersoffatmass,insulinsensitivityandinflammation:G.Flehmig,etal.;PLoSOne9,e99785(2014)
- Amyloiddepositioninamousemodelhumanizedatthetransthyretinandretinol-bindingprotein4loci:X.Li,etal.;Lab.Investig.(epubaheadofprint)(2018)
- DevelopmentofamouseIgAmonoclonalantibody-basedenzyme-linkedimmunosorbentsandwichassayfortheanalysesofRBP4:N.S.Lee,etal.;Sci.Rep.8,2578(2018)
品牌介绍
Adipogen公司由三个子公司组成,分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国,运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发,如癌症、免疫、炎症、代谢疾病(糖尿病、肥胖)、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外,也可提供抗体和蛋白产品,Adipogen拥有自己的化学实验室,致力于开发创新型小分子化合物。
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