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当前位置: 首页 > 产品中心 > Sandwich_method_ELISA > Adipogen/RBP4 (human) Competitive ELISA Kit/AG-45A-0010YTP-KI01/2 x 96 wells
商品详细Adipogen/RBP4 (human) Competitive ELISA Kit/AG-45A-0010YTP-KI01/2 x 96 wells
Adipogen/RBP4 (human) Competitive ELISA Kit/AG-45A-0010YTP-KI01/2 x 96 wells
Adipogen/RBP4 (human) Competitive ELISA Kit/AG-45A-0010YTP-KI01/2 x 96 wells
商品编号: AG-45A-0010YTP-KI01
品牌: Adipogen Inc
市场价: ¥17000.00
美元价: 10200.00
产地: 美国(厂家直采)
公司:
产品分类: 夹心法ELISA
公司分类: Sandwich_method_ELISA
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
MoreInformation
ProductDetails
SynonymsRetinolBindingProtein4
ProductTypeKit
Properties
ApplicationSetQuantitativeELISA
SpecificityDetectshumanRBP4.Doesnotcross-reactwithhumanADIponectin,humanresistinorhumanRELM-β.
CrossreactivityHuman
Quantity1x96wells
Sensitivity1ng/ml
Range0.001to5μg/ml
SampleTypeCellCultureSupernatant
Plasma
Serum
Urine
AssayTypeCompetitive
DetectionTypeColorimetric
ShippingandHandling
ShippingBLUEICE
ShortTermStorage+4°C
LongTermStorage+4°C
HandlingAdviceAfterstandardreconstitution,preparealiquotsandstoreat-20°C.
Avoidfreeze/thawcycles.
Plateandreagentsshouldreachroomtemperaturebeforeuse.
Use/StABIlity12monthsafterthedayofmanufacturing.SeeexpirydateonELISAKitbox.
Documents
ManualDownloadPDF
MSDSDownloadPDF
ProductSpecificationSheet
DatasheetDownloadPDF
Retinolbindingprotein4(RBP4;RBP)isa21kDasecretedprotein,amemberofthelipocalinfamilyandisknownastheprimarytransporterofretinol(vitaminA)totissues.ArecentreportrevealedRBP4asanadipokinelinkingglucosetransporter4(GLUT4)suppressioninadiposetissuetoinsulin.ElevatedhumanandmouseserumRBP4levelsareassociatedwithinsulinresistanceanditsseverity,obesityandcertaincomponentsofmetabolicsyndrome.FurThermore,humanserumRBP4levelsarecloselyrelatedtorenalfunctionandrecentstudieshaveshownanassociationbetweenserumRBP4levelsandurinaryalbuminexcretion.TheurinaryRBP4concentrationmaybeavaluableMarkerforboth,insulinresistanceandmicroalbuminuriaininsulin-resistantsubjects.
ProductReferences
  1. Retinol-bindingprotein4inhumanobesity:J.Janke,etal.;Diabetes55,2805(2006)
  2. Plasmaretinol-bindingprotein-4concentrationsareelevatedinhumansubjectswithimpairedglucosetoleranceandtype2diabetes:Y.M.Cho,etal.;DiabetesCare29,2457(2006)
  3. Associationofserumretinolbindingprotein4andinsulinresistanceinapparentlyhealthyadolescents:D.C.Leeetal.;Metab.Clin.Exp.56,327(2007)
  4. Highcirculatingretinol-bindingprotein4isassociatedwithelevatedliverfat,butnotwithtotal-,subcutaneous-,visceral-,orintramyocellularfatinhumans:N.Stefanetal.;DiabetesCare30,1173(2007)
  5. Retinol-bindingprotein4asaplasmabiomarkerofrenaldysfunctionandcardiovasculardiseaseintype2diabetes:A.Cabre,etal.;J.Intern.Med.262,496(2007)
  6. Visceraladiposityisassociatedwithserumretinolbindingprotein-4levelsinhealthywomen:J.W.Lee,etal.;Obesity(SilverSpring)15,2225(2007)
  7. Circulatingretinol-bindingprotein-4,insulinsensitivity,insulinsecretion,andinsulindispositionindexinobeseandnonobesesubjects:responsetoBrochetal:N.Stefan,etal.;DiabetesCare30,e91(2007)
  8. InsulinresistanceisunrelatedtocirculatingretinolbindingproteinandproteinCinhibitor:M.Promintzer,etal.;J.Clin.Endocrinol.Metab.92,4306(2007)
  9. Serumlevelsofadipokineretinol-bindingprotein-4inrelationtorenalfunction:M.Ziegelmeier,etal.;DiabetesCare30,2588(2007)
  10. Serumretinol-bindingprotein4levelsareelevatedinnon-alcoholicfattyliverdisease:J.A.Seo,etal.;Clin.Endocrinol.(Oxf)68,555(2008)
  11. Retinolbindingprotein-4elevationisassociatedwithserumthyroid-stimulatinghormonelevelindependentlyofobesityinelderlysubjectswithnormalglucosetolerance:S.H.Choi,etal.;J.Clin.Endocrinol.Metab.93,2313(2008)
  12. Retinolbindingprotein4concentrationsareinfluencedbyrenalfunctioninpatientswithtype2diabetesmellitus:T.Masaki,etal.;Metabolism57,1340(2008)
  13. Highplasmaretinolbindingprotein-4andlowplasmaadiponectinconcentrationsareassociatedwithseverityofglucoseintoleranceinwomenwithpreviousgestationaldiabetesmellitus:S.H.Choi,etal.;J.Clin.Endocrinol.Metab.93,3142(2008)
  14. Decreasedclearanceofserumretinol-bindingproteinandelevatedlevelsoftransthyretinininsulin-resistantob/obmice:N.Mody,etal.;Am.J.Physiol.Endocrinol.Metab.294,E785(2008)
  15. Identificationofserumbiomarkersinbrain-injuredadults-potentialforpredictingelevatedintracranialpressure:G.Hergenroeder,etal.;J.Neurotrauma25,79(2008)
  16. Retinolbindingprotein4:anewmarkerofvirus-inducedsteatosisinpatientsinfectedwithHepatitisCvirusgenotype1:S.Petta,etal.;Hepatology48,28(2008)
  17. Insulin-SensitizingEffectsofExerciseonAdiponectinandRetinol-BindingProtein-4ConcentrationsinYoungandMiddle-AgedWomen:S.Lim,etal.;J.Clin.Endocrinol.Metab.93,2263(2008)
  18. Circulatingretinol-bindingprotein-4concentrationmightreflectinsulinresistance-associatedironoverload:J.M.Fernández-Real,etal.;Diabetes57,1918(2008)
  19. Associationbetweenserumretinol-bindingprotein4andsmalldenselow-densitylipoproteincholesterollevelsinyoungadultwomen:S.Usui,etal.;Clin.Chim.Acta399,45(2009)
  20. SerumAdipocyteFattyAcid–BindingProteinLevelsAreAssociatedWithNonalcoholicFattyLiverDiseaseinType2DiabeticPatients:J.H.Koh,etal.;DiabetesCare32,147(2009)
  21. Elevatedserumg-glutamyltransferaselevelsareindependentlyassociatedwithinsulinresistanceinnon-diabeticsubjects:J.Y.Shin,etal.;DiabetesRes.Clin.Pract.84,152(2009)
  22. ClinicalImplicationsofSerumRetinol-BindingProtein4inAsthmaticChildren:Y.H.Park,etal.;J.KoreanMed.Sci.24,1010(2009)
  23. EffectofexercisetrainingonA-FABP,lipocalin-2andRBP4levelsinobesewomen:K.M.Choi,etal.;Clin.Endocrinol.70,569(2009)
  24. Circuitresistanceexerciseimprovesglycemiccontrolandadipokinesinfemaleswithtype2diabetesmellitus:S.Kang,etal.;JSSM8,682(2009)
  25. VisceralObesityisAssociatedwiththeMetabolicSyndromeandElevatedPlasmaRetinolBindingProtein-4LevelinObstructiveSleepApneaSyndrome:S.Makino,etal.;Horm.Metab.Res.41,221(2009)
  26. PatientsachievingclearanceofHCVwithinterferontherapyrecoverfromdecreasedretinol-bindingprotein4levels:M.Iwasa,etal.;J.ViralHepat.16,716(2009)
  27. ChangeinSerumAdipocytokinesafterRecoveryofThyroidFunctionandWeightinPatientswithGraves"Disease:H.Y.Jung,etal.;Korean.J.Obes.18,47(2009)[Korean]
  28. Macrophagesarenovelsitesofexpressionandregulationofretinolbindingprotein-4(RBP4):M.Broch,etal.;Physiol.Res.59,299(2010)
  29. CombinedImpactofAdiponectinandRetinol-bindingProtein4onMetabolicSyndromeinElderlyPeople:TheKoreanLongitudinalStudyonHealthandAging:S.Lim,etal.;Obesity18,826(2010)
  30. Elevatedserumretinol-bindingprotein4isassociatedwithinsulinresistanceinolderwomen:J.B.Suh,etal.;Metabolism59,118(2010)
  31. TheAPOA5?1131T>CvariantenhancestheassociationbetweenRBP4andhypertriglyceridemiaindiabetes:A.Cabré,etal.;Nutr.Metab.Cardiovasc.Dis.20,243(2010)
  32. APOHisincreasedintheplasmaandliveroftype2diabeticpatientswithmetabolicsyndrome:A.Castro,etal.;Atherosclerosis209,201(2010)
  33. Elevationofplasmaretinol-bindingprotein4andreductionofplasmaadiponectininsubjectswithcerebralinfarction:M.Sasaki,etal.;Metabolism59,527(2010)
  34. Associationofinsulinresistancewithanti-Mullerianhormonelevelsinwomenwithoutpolycysticovarysyndrome(PCOS):H.T.Park,etal.;Clin.Endocrinol.(Oxf)72,26(2010)
  35. Dailyphysicalactivity,fastingglucose,uricacid,andbodymassindexareindependentfactorsassociatedwithserumfibroblastgrowthfactor21levels:D.Cuevas-Ramos,etal.;Eur.J.Endocrinol.163,469(2010)
  36. Adipokinepatterninsubjectswithimpairedfastingglucoseandimpairedglucosetoleranceincomparisontonormalglucosetoleranceanddiabetes:A.Tönjes,etal.;PLoSOne.5,e13911(2010)
  37. Macrophagesarenovelsitesofexpressionandregulationofretinolbindingprotein-4(RBP4):M.Broch,etal.;Physiol.Res.59,299(2010)
  38. Serumlevelsofplacentalgrowthfactorandretinol-bindingprotein-4inpregnancy-inducedhypertensivewomen:A.F.Al-Kholy,etal.;J.Am.Sci.6,448(2010)
  39. Elevatedserumretinol-bindingprotein4isassociatedwithinsulinresistanceinolderwomen:J.B.Suh,etal.;Metabolism.59,118(2010)
  40. TheAPOA5-1131T>CvariantenhancestheassociationbetweenRBP4andhypertriglyceridemiaindiabetes:A.Cabré,etal.;Nutr.Metab.Cardiovasc.Dis.20,243(2010)
  41. Comparativeanalysisofserumproteomesofpatientswithcardiovasculardisease:H.J.Kim,etal.;Clin.Biochem.44,178(2011)
    Relationshipofserumretinol-bindingprotein4withweightstatusandlipidprofileamongKoreanchildrenandadults:I.K.Kim,etal.;Eur.J.Clin.Nutr.65,226(2011)
  42. Identificationoftuberculosis-associatedproteinsinwholebloodsupernatant:T.Tanaka,etal.;BMCInfect.Dis.11,71(2011)
  43. CirculatingNamptandRBP4levelsinpatientswithcarotidstenosisundergoingcarotidendarterectomy(CEA):G.Aust,etal.;Clin.Chim.Acta.412, 1195(2011)
  44. HighliverRBP4proteincontentisassociatedwithhistologicalfeaturesinpatientswithgenotype1chronichepatitisCandwithnonalcoholicsteatohepatitis:S.Petta,etal.;Dig.LiverDis.43,404(2011)
  45. Serumadipocytefattyacid-bindingprotein,retinol-bindingprotein4,andadiponectinconcentrationsinrelationtothedevelopmentofthemetabolicsyndromeinKoreanboys:a3-yProspectivecohortstudy:K.M.Choi,etal.;Am.J.Clin.Nutr.93,19(2011)
  46. Telmisartanreducesneointimavolumeandpulsewavevelocity8monthsafterzotarolimus-elutingstentimplantationinhypertensivetype2diabeticpatients:S.J.Hong,etal.;Heart97,1425(2011)
  47. Retinol-bindingprotein4andperoxisomeproliferator-activatedreceptor-γinsteatoticlivertransplantation:A.Casillas-Ramírez,etal.;JPET338,143(2011)
  48. Optimalcutpointsofwaistcircumference(WC)andvisceralfatarea(VFA)predictingformetabolicsyndrome(MetS)inelderlypopulationintheKoreanLongitudinalStudyonHealthandAging(KLoSHA):S.Lim,etal.;Arch.Gerontol.Geriatr.54,e29(2012)
  49. Increasedplasmalevelsofretinol-bindingprotein4withvisceralobesityisassociatedwithcardiovascularriskfactors:J.C.Won,etal.;J.Diabet.Inv.3,457(2012)
  50. Circulatinglevelsofadiponectin,leptin,fetuin-aandretinol-bindingproteininpatientswithtuberculosis:markersofmetabolismandinflammation:N.Keicho,etal.;PLoSOne7,e38703(2012)
  51. Endothelialimpairmentandbonemarrow-derivedCD34+/133+cellsindiabeticpatientswitherectiledysfunction:M.Murata,etal.;J.Diab.Invest.3,526(2012)
  52. ComparisonofregionalbodycompositionanditsrelationwithcardiometabolicriskbetweenBMI-matchedyoungandoldsubjects:Y.Lee,etal.;Atherosclerosis224,258(2012)
  53. Associationofsubcutaneousandvisceralfatmasswithserumconcentrationsofadipokinesinsubjectswithtype2diabetesmellitus:T.Saito,etal.;Endocr.J.59,39(2012)
  54. ImpactofSerumRetinol-BindingProtein4LevelsonRegulationofRemnant-LikeParticlesTriglycerideinType2DiabetesMellitus:N.Yamaaki,etal.;J.Diabet.Res.2013,ID143515(2013)
  55. Crosstalkbetweencirculatingperoxisomeproliferator-activatedreceptorgamma,adipokinesandmetabolicsyndromeinobesesubjects:K.Mirzaei,etal.;Diabetol.Metabol.Syndr.5,79(2013)
  56. Associationsofretinol-bindingprotein4withoxidativestress,inflammatorymarkers,andmetabolicsyndromeinamiddle-agedandelderlyChinesepopulation:Y.Liu,etal.;Diabetol.Metab.Syndr.6,25(2014)
  57. Adipokinesmaymediatetherelationshipbetweenrestingmetabolicratesandbonemineraldensitiesinobesewomen:S.Moradi,etal.;Osteoporos.Int.doi:10.1007/s00198-017-3914-6(2017)
品牌介绍
Adipogen公司由三个子公司组成,分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国,运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发,如癌症、免疫、炎症、代谢疾病(糖尿病、肥胖)、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外,也可提供抗体和蛋白产品,Adipogen拥有自己的化学实验室,致力于开发创新型小分子化合物。