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Adipogen/RBP4 (mouse/rat) Dual ELISA Kit/AG-45A-0012YTP-KI01/2 x 96 wells
Adipogen/RBP4 (mouse/rat) Dual ELISA Kit/AG-45A-0012YTP-KI01/2 x 96 wells
商品编号：
AG-45A-0012YTP-KI01
品牌：
Adipogen Inc
市场价：
¥16400.00
美元价：
9840.00
产品分类：
夹心法ELISA
公司分类：
Sandwich_method_ELISA
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| ProductDetails | |
|---|---|
| Synonyms | RetinolBindingProtein4 |
| ProductType | Kit |
| Properties | |
| ApplicationSet | QuantitativeELISA |
| Specificity | DetectsmouseandratRBP4.Doesnotcross-reactwithhumanRBP4,mouseADIponectin,mouseresistin,mouseNampt,ratadiponectin,ratresistinorratNampt. |
| Crossreactivity | Mouse Rat |
| Quantity | 1x96wells |
| Sensitivity | 60pg/ml |
| Range | 0.188to12ng/ml |
| SampleType | CellCultureSupernatant Serum Urine |
| AssayType | Sandwich |
| DetectionType | Colorimetric |
| ShippingandHandling | |
| Shipping | BLUEICE |
| ShortTermStorage | +4°C |
| LongTermStorage | +4°C |
| HandlingAdvice | Afterstandardreconstitution,preparealiquotsandstoreat-20°C. Avoidfreeze/thawcycles. Plateandreagentsshouldreachroomtemperaturebeforeuse. |
| Documents | |
| Manual |  DownloadPDF |
| MSDS | DownloadPDF |
| ProductSpecificationSheet | |
| Datasheet | DownloadPDF |
Retinolbindingprotein4(RBP4;RBP)isa21kDasecretedprotein,amemberofthelipocalinfamilyandisknownastheprimarytransporterofretinol(vitaminA)totissues.ArecentreportrevealedRBP4asanadipokinelinkingglucosetransporter4(GLUT4)suppressioninadiposetissuetoinsulin.ElevatedhumanandmouseserumRBP4levelsareassociatedwithinsulinresistanceanditsseverity,obesityandcertaincomponentsofmetabolicsyndrome.FurThermore,humanserumRBP4levelsarecloselyrelatedtorenalfunctionandrecentstudieshaveshownanassociationbetweenserumRBP4levelsandurinaryalbuminexcretion.TheurinaryRBP4concentrationmaybeavaluableMarkerforboth,insulinresistanceandmicroalbuminuriaininsulin-resistantsubjects.
ProductReferences
- Plasmaretinol-bindingprotein-4concentrationsareelevatedinhumansubjectswithimpairedglucosetoleranceandtype2diabetes:Y.M.Cho,etal.;DiabetesCare29,2457(2006)
- Highcirculatingretinol-bindingprotein4isassociatedwithelevatedliverfatbutnotwithtotal,subcutaneous,visceral,orintramyocellularfatinhumans:N.Stefan,etal.;DiabetesCare30,1173(2007)
- Cyanidin3-glucosideameliorateshyperglycemiaandinsulinsensitivityduetodownregulationofretinolbindingprotein4expressionindiabeticmice:R.Sasaki,etal.;Biochem.Pharmacol.74,1619(2007)
- Decreasedclearanceofserumretinol-bindingproteinandelevatedlevelsoftransthyretinininsulin-resistantob/obmice:N.Mody,etal.;Am.J.Physiol.Endocrinol.Metab.294,E785(2008)
- Identificationandcharacterizationofanon-retinoidligandforretinolbindingprotein4whichlowersserumretinol-bindingprotein4levelsinvivo:A.Motani,etal.;J.Biol.Chem.284,7673(2009)
- Effectofdietarymonosodiumglutamateontransfat-inducednonalcoholicfattyliverdisease:K.S.Collison,etal.;J.LipidRes.50,1521(2009)
- DiabetesoftheLiver:TheLinkBetweennonalcoholicfattyliverdiseaseandHFCS-55:K.S.Collison,etal.;Obesity17,2003(2009)
- Earlypostnataloestradiolexposurecausesinsulinresistanceandsignsofinflammationincirculationandskeletalmuscle:C.Alexanderson,etal.;J.Endocrinol.201,49(2009)
- Dietarytrans-fatcombinedwithmonosodiumglutamateinducesdyslipidemiaandimpairsspatialmemory:K.S.Collison,etal.;Physiol.Behav.99,334(2010)
- EffectofdietarymonosodiumglutamateonHFCS-inducedhepaticsteatosis:expressionprofilesintheliverandvisceralfat:K.S.Collison,etal.;Obesity(SilverSpring)18,1122(2010)
- Dietaryanthocyanin-richbilberryextractameliorateshyperglycemiaandinsulinsensitivityviaactivationofAMP-activatedproteinkinaseindiabeticmice:M.Takikawa,etal.;J.Nutr.140,527(2010)
- IncreasedlipidaccumulationinliverandwhiteadiposetissueinagingintheSAMP10mouse:T.Honma,etal.;J.Nutr.Sci.Vitaminol.(Tokyo)57,123(2011)
- Elevatedretinolbindingprotein4contributestoinsulinresistanceinspontaneouslyhypertensiverats:H.Y.Ou,etal.;Horm.Metab.Res.43,312(2011)
- Suppressionofretinol-bindingprotein4withRNAoligonucleotidepreventshigh-fatdiet-inducedmetabolicsyndromeandnon-alcoholicfattyliverdiseaseinmice:Y.Tan,etal.;Biochim.Biophys.Acta1811,1045(2011)
- Effectsofhesperidinontheprogressionofhypercholesterolemiaandfattyliverinducedbyhigh-cholesteroldietinrats:X.Wang,etal.;J.Pharmacol.Sci.117,129(2011)
- PeroxisomeProliferator-ActivatedReceptors-αand-γ,andcAMP-MediatedPathways,ControlRetinol-BindingProtein-4GeneExpressioninBrownAdiposeTissue:M.Rosell,etal.;Endocrinol. 153, 1162(2012)
- CaffeicAcidPhenylethylAmideProtectsagainsttheMetabolicConsequencesinDiabetesMellitusInducedbyDietandStreptozocin:Y.C.Weng,etal.;Evid.BasedComplement.Alternat.Med.2012, ID984780(2012)
- Blueberrypolyphenol-enrichedsoybeanflourreduceshyperglycemia,bodyweightgainandserumcholesterolinmice:D.E.Roopchand,etal.;Pharmacol.Res.68,59(2012)
- Evaluationoftherelativeperformanceof12urinarybiomarkersforrenalsafetyacross22ratsensitivityandspecificitystudies:K.Vlasakova,etal.;Toxicol.Sci.138,3(2013)
- AssociationofurinaryRBP4withinsulinresistance,inflammation,andmicroalbuminuria:S.E.Park,etal.;Eur.J.Endocrin.171,443(2014)
- HepatocytesaretheprincipalsourceofcirculatingRBP4inmice:S.J.Thompson,etal.;Diabetes66,58(2017)
品牌介绍
Adipogen公司由三个子公司组成，分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国，运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发，如癌症、免疫、炎症、代谢疾病（糖尿病、肥胖）、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外，也可提供抗体和蛋白产品，Adipogen拥有自己的化学实验室，致力于开发创新型小分子化合物。
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