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脂肪原/Nampt（内脂素/PBEF）（人）ELISA试剂盒/AG-45A-0006YTP-KI01/2 x 96孔
脂肪原/Nampt（内脂素/PBEF）（人）ELISA试剂盒/AG-45A-0006YTP-KI01/2 x 96孔
商品编号：
AG-45A-0006YTP-KI01
品牌：
Adipogen Inc
市场价：
¥22000.00
美元价：
13200.00
产品分类：
夹心法ELISA
公司分类：
Sandwich_method_ELISA
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| ProductDetails | |
|---|---|
| Synonyms | NicotinamidePhosphoribosyltransferase;PBEF1;Pre-BCellColonyEnhancingFactor1 |
| ProductType | Kit |
| Properties | |
| ApplicationSet | QuantitativeELISA |
| Specificity | DetectshumanNampt.Weaklycross-reacts(<15%) with="" mouse="" nampt="" and="" rat="" nampt.="" does="" not="" cross-react="" with="" human="" adiponectin,="" human="" resistin,="" human="" vaspin="" or="" human="" rbp4.="" has="" been="" shown="" to="" specifically="" detect="" the="" physiologically="" relevant="" nampt="" dimer="" in="" human="" serum="" samples.=""> |
| Crossreactivity | Human |
| Quantity | 1x96wells 2x96wells(TwinPlex) |
| Sensitivity | 30pg/ml |
| Range | 0.125to8ng/ml |
| SampleType | Serum |
| AssayType | Sandwich |
| DetectionType | Colorimetric |
| OtherProductData | Note:Doesnotworkwithplasmasamples. |
| ShippingandHandling | |
| Shipping | BLUEICE |
| ShortTermStorage | +4°C |
| LongTermStorage | +4°C |
| HandlingAdvice | Afterstandardreconstitution,preparealiquotsandstoreat-20°C. Avoidfreeze/thawcycles. Plateandreagentsshouldreachroomtemperaturebeforeuse. |
| Use/StABIlity | 12monthsafterthedayofmanufacturing.SeeexpirydateonELISAKitbox. |
| Documents | |
| Manual |  DownloadPDF |
| MSDS | DownloadPDF |
| ProductSpecificationSheet | |
| Datasheet | DownloadPDF |
Nicotinamidephosphoribosyltransferase(Nampt;pre-Bcellcolony-enhancingfactor;PBEF;Visfatin)isan52kDAADIpokinesecretedbyadiposetissueandinvolvedinthebiosynthesisofnicotinamideadeninedinucleotide(NAD+).TwoformsofNamptexist,anintracellularform(iNampt)andanextracellularform(eNampt).WhilethefunctionofiNamptasanessentialandrate-limitingNAD+biosyntheticenzymeiswellestablished,thephysiologicalroleofeNamptisstillamatterofdebate.IthasbeenshownthatNamptexpressionisincreasedindifferentdiseases,likediabetes,obesity,fetalgrowthretardation,sepsis,inflammatoryboweldisease,Crohn’sdiseaseandrheumatoidarthritis.FurThermore,NamptmightbeaMarkerofpre-eclampsiaandofendothelialhealth.RecentlyitwasreportedthatVisfatinlevelswerehigherintheunstablecarotidatheroscleroticplaquethaninnon-atheroscleroticmammaryarterysecretomes,suggestingapossIBLelinkbetweenvisfatinandunstablecarotidatheroscleroticplaque.
ProductReferences
- Visfatinispresentinbovinemammaryepithelialcells,lactatingmammaryglandandmilk,anditsexpressionisregulatedbycAMPpathway:T.Yonezawa,etal.;FEBSLett.580,6635(2006)
- Molecularcharacteristicsofserumvisfatinanddifferentialdetectionbyimmunoassays:A.Koerner,etal.;J.Clin.Endocrinol.Metab.92,4783(2007)
- Serumlevelsoftheadipokinevisfatinareincreasedinpre-eclampsia:M.Fasshauer,etal.;Clin.Endocrinol.69,69(2008)
- Correlationofcirculatingfull-lengthvisfatin(PBEF/Nampt)withmetabolicparametersinsubjectswithandwithoutdiabetes:across-sectionalstudy:R.Retnakaran,etal.;Clin.Endocrinol.69,885(2008)
- LongitudinalchangesinpancreaticandadipocytehormonesfollowingRoux-en-Ygastricbypasssurgery:M.M.Swarbrick,etal.;Diabetologia51,1901(2008)
- Adipokinesinfluencingmetabolicandcardiovasculardiseasearedifferentiallyregulatedinmaintenancehemodialysis:M.Ziegelmeier,etal.;Metabolism57,1414(2008)
- Serumvisfatinanditsrelationtoinsulinresistanceandinflammationintype2diabeticpatientswithandwithoutmacroangiopathy:A.A.Alghasham&Y.A.Barakat;SaudiMed.J.29,185(2008)
- Ethnic-specificCorrelationsofVisfatinWithCirculatingMarkersofEndothelialInflammationandFunction:M.Reimann,etal.;Obesity17,2210(2009)
- VisfatinactivateseNOSviaAktandMAPkinasesandimprovesendothelialcellfunctionandangiogenesisinvitroandinvivo:translationalimplicationsforatherosclerosis:F.Lovren,etal.;Am.J.Physiol.Endocrinol.Metab.296,E1440(2009)
- Circulatingvisfatininchronicobstructivepulmonarydisease:X.Liu,etal.;Nutrition25,373(2009)
- Visfatiningestationaldiabetes:serumlevelandmRNAexpressioninfatandplacentaltissue:B.Telejko,etal.;DiabetesRes.Clin.Pract.84,68(2009)
- Plasmavisfatinconcentrationsafteralifestyleinterventionweredirectlyassociatedwithinflammatorymarkers:S.Bo,etal.;Nutr.Metab.Cardiovasc.Dis.19,423(2009)
- Releaseof12AdipokinesbyAdiposeTissue,NonfatCells,andFatCellsFromObeseWomen:J.N.Fain,etal.;Obesity(SilverSpring)18,890(2009)
- Plasmavisfatinandghrelinresponsetoprolongedscullingincompetitivemalerowers:J.Jurimae,etal.;Med.Sci.SportsExerc.41,137(2009)
- Visfatiningestationaldiabetes:serumlevelandmRNAexpressioninfatandplacentaltissue:B.Telejko,etal.;DiabetesRes.Clin.Pract.84,68(2009)
- Adipokinesandsystemiclupuserythematosus:relationshipwithmetabolicsyndromeandcardiovasculardiseaseriskfactors:M.Vadacca,etal.;J.Rheumatol.36,295(2009)
- ActivevisfatiniselevatedinserumofmaintenancehaemodialysispatientsandcorrelatesinverselywithcirculatingHDLcholesterol:K.D.Nusken,etal.;Nephrol.Dial.Transplant.24,2832(2009)
- Alterationofadipokinesduringperipheralbloodstemcellmobilizationinducedbygranulocytecolony-stimulatingfactor:Y.Tanaka,etal.;J.Clin.Apheresis24,205(2009)
- Peritonealfluidadipokines:readyforprimetime?R.Wiest,etal.;Eur.J.Clin.Invest.39,219(2009)
- Relationshipbetweengenotypeandserumlevelsofadipokinesandbonemineraldensityintype2diabetesmellituspatients:K.Mirzaei,etal.;Iran.J.Diab.Lip.Dis.8,77(2009)
- Adipocytokinelevelsingastriccancerpatients:resistinandvisfatinasbiomarkersofgastriccancer:T.E.Nakajima,etal.;J.Gastroenterol.44,685(2009)
- Variationinthevisfatingenemayaltertherequireddosageoforalantidiabeticagentsintype2diabeticpatients:K.Mirzaei,etal.;Iran.J.Diab.Lip.Dis.8,87(2009)
- VisfatinisapositiveregulatorofMCP-1inhumanadipocytesinvitroandinmiceinvivo:G.Sommer,etal.;Obesity18,1486(2010)
- A12-weekregimenofcaloricrestrictionimproveslevelsofadipokinesandpro-inflammatorycytokinesinKoreanwomenwithBMIsgreaterthan23kg/m2:I.S.Lee,etal.;Inflamm.Res.59,399(2010)
- Nicotinamidephosphoribosyltransferase(NAMPT/PBEF/visfatin)isconstitutivelyreleasedfromhumanhepatocytes:A.Garten,etal.;BBRC391,376(2010)
- Therelationshipbetweenvisfatinandmetabolicsyndromeinpostmenopausalwomen:J.H.Kim,etal.;Maturitas67,67(2010)
- Transcriptomeanalysisofmonocyte-HIVinteractions:R.VandenBergh,etal.;Retrovirology7,53(2010)
- Adipokinesandcardiometabolicfunction:Howaretheyinterlinked?:A.E.Schutte,etal.;Regul.Pept.164,133(2010)
- A12-weekregimenofcaloricrestrictionimproveslevelsofadipokinesandpro-inflammatorycytokinesinKoreanwomenwithBMIsgreaterthan23kg/m2:I.S.Lee,etal.;Inflamm.Res.59,399(2010)
- Splanchnicconcentrationsandpostprandialreleaseofvisceraladipokines:R.Wiest,etal.;Metabolism59,664(2010)
- Adipocytokinesasnewpromisingmarkersofcolorectaltumors:adiponectinforcolorectaladenoma,andresistinandvisfatinforcolorectalcancer:T.E.Nakajima,etal.;CancerSci.101,1286(2010)
- Effectofgreenteaextractonboneturnovermarkersintype2diabeticpatients;Adouble-blind,placebo-controlledclinicaltrialstudy:K.Mirzaei,etal.;DARUJ.Pharm.Sci.17(Suppl1),38(2010)
- Adipocytokinesandbonemineraldensityinadolescentfemaleathletes:R.Gruodyte,etal.;ActaPaediatr.99,1879(2010)
- Serumvisfatinisassociatedwithtype2diabetesmellitusindependentofinsulinresistanceandobesity:A.Esteghamati,etal.;DiabetesRes.Clin.Pract.91,154(2011)
- Plasmavisfatinandadiponectinconcentrationsinphysicallyactiveadolescentgirls:relationshipswithinsulinsensitivityandbodycompositionvariables:J.Jurimae,etal.;JPEM24,419(2011)
- Serumvisfatinandvaspinlevelsinprepubertalchildren:effectofobesityandweightlossafterbehaviormodificationsontheirsecretionandrelationshipwithglucosemetabolism:G.A.Martos-Moreno,etal.;Int.J.Obes.(Lond)35,1355(2011)
- AdmissionVisfatinLevelsPredictPancreaticandPeripancreaticNecrosisinAcutePancreatitisandCorrelateWithClinicalSeverity:A.Schaeffler,etal.;Am.J.Gastroenterol.106,957(2011)
- CirculatingNamptandRBP4levelsinpatientswithcarotidstenosisundergoingcarotidendarterectomy(CEA):G.Aust,etal.;Clin.Chim.Acta.412,1195(2011)
- Theeffectofomega-3ontheserumvisfatinconcentrationinpatientswithtypeIIdiabetes:H.Hajianfar,etal.;JRMS16,490(2011)
- Pre-B-cellcolony-enhancingfactoranditsclinicalcorrelateswithacutelunginjuryandsepsis:K.A.Lee&M.N.Gong;Chest140,382(2011)
- Full-lengthvisfatinlevelsareassociatedwithinflammationinwomenwithpolycysticovarysyndrome:T.K.Lajunen,etal.;Eur.J.Clin.Invest.42,321(2011)
- Possibleroleofvisfatininhepatomaprogressionandtheeffectsofbranched-chainaminoacidsonvisfatin-inducedproliferationinhumanhepatomacells:S.Ninomiya,etal.;CancerPrev.Res.(Phila)4,2092(2011)
- Type2diabetesandlipoproteinmetabolismaffectLPS-inducedcytokineandchemokinereleaseinprimaryhumanmonocytes:M.Bala,etal.;Exp.Clin.Endocrinol.Diabetes119,370(2011)
- Comparetheeffectsofdifferentvisfatinconcentrationoncardiovascularriskfactors,adiponectinandinsulinresistanceinpatientswithT2DM:S.Mohammadi,etal.;Diab.Metab.Syndr:Clin.Res.Rev.5,71(2011)
- Visfatinissecretedintothebreastmilkandiscorrelatedwithweightchangesoftheinfantafterthebirth:J.Bienertova-Vasku,etal.;DiabetesRes.Clin.Pract.96,355(2012)
- Increasedlevelsandadiposetissueexpressionofvisfatininmorbidlyobesewomen.Therelationshipwithpro-inflammatorycytokines:X.Terra,etal.;Clin.Endocrinol.(Oxf.)77,691(2012)
- Serumvisfatinconcentrationsingestationaldiabetesmellitusandnormalpregnancy:N.Rezvan,etal.;Arch.Gynecol.Obstet.285,1257(2012)
- Serumvisfatinandvaspinlevelsinnormoglycemicfirst-degreerelativesofIranianpatientswithtype2diabetesmellitus:S.Akbarzadeh,etal.;DiabetesRes.Clin.Pract.95,132(2012)
- ExtracellularATPinducesP2X7-dependentnicotinamidephosphoribosyltransferasereleaseinLPS-activatedhumanmonocytes:E.Schilling&S.Hauschildt;InnateImmun.18,738(2012)
- TheValueofVisfatininthePredictionofMetabolicSyndrome:AMulti-FactorialAnalysis:A.Esteghamati,etal.;J.Cardiovasc.Transl.Res.5,541(2012)
- Theeffectsofomega-3onbloodpressureandtherelationshipbetweenserumvisfatinlevelandbloodpressureinpatientswithtypeIIdiabetes:M.J.Hosseinzadeh-Attar,etal.;ARYAAtheroscler.8,1(2012)
- Associationofsleeponsetofacutecoronarysyndromewithsleepapneasyndromeandabnormaldiurnalvariationofhemostasisandadipokinelevels:Y.Yano,etal.;BloodCoagul.Fibrinolysis23,590(2012)
- Omentin-1,visfatinandadiponectinlevelsinrelationtobonemineraldensityinIranianpostmenopausalwomen:M.Tohidi,etal.;Bone51,876(2012)
- LipidProfilesandSerumVisfatinConcentrationsinPatientswithTypeIIDiabetesinComparisonwithHealthyControls:H.Hajianfar,etal.;Int.J.Prev.Med.3,326(2012)
- Effectofsubstitutingsaturatedwithmonounsaturatedfattyacidsonserumvisfatinlevelsandinsulinresistanceinoverweightwomen:Arandomizedcross-overclinicaltrial:F.Haghighatdoost,etal.;Int.J.FoodSci.Nutr.63,772(2012)
- Plasmavisfatinlevelsandgeneexpressioninmorbidlyobesewomenwithassociatedfattyliverdisease:T.Auguet,etal.;Clin.Biochem.46,202(2013)
- Portalandsystemiclevelsofvisfatininmorbidlyobesesubjectsundergoingbariatricsurgery:Z.Karbaschian,etal.;Endocrine44,114(2013)
- Associationsofmetabolicfactorsandadipokineswithpaininincipientupperextremitysofttissuedisorders:across-sectionalstudy:M.Rechardt,etal.;BMJOpen3,e003036(2013)
- Admissionplasmavisfatinlevelstronglycorrelateswithhematomagrowthandearlyneurologicdeteriorationinpatientswithacutespontaneousbasalgangliahemorrhage:S.J.Gu,etal.;Clin.Chim.Acta.425,85(2013)
- Effectofweightreductionfollowingbariatricsurgeryonserumvisfatinandadiponectinlevelsinmorbidlyobesesubjects:M.J.Hosseinzadeh-Attar,etal.;Obes.Facts6,193(2013)
- Expressionandregulationofnamptinhumanislets:K.Kover,etal.;PLoSOne8,e58767(2013)
- VisfatinasaNovelMediatorReleasedbyInflamedHumanEndothelialCells:T.Romacho,etal.;PLoSOne8,e78283(2013)
- Adipocytokineprofile,cytokinelevelsandfoxp3expressioninmultiplesclerosis:apossiblelinktosusceptibilityandclinicalcourseofdisease:S.Emamgholipour,etal.;PLoSOne8,e76555(2013)
- Associationsbetweentissuevisfatin/nicotinamide,phosphoribosyltransferase(Nampt),retinolbindingprotein-4,andvaspinconcentrationsandinsulinresistanceinmorbidlyobesesubjects:Z.Goktas,etal.;MediatorsInflamm.2013,861496(2013)
- Expressionandfunctionofvisfatin(Nampt),anadipokine-enzymeinvolvedininflammatorypathwaysofosteoarthritis:M.C.Laiguillon,etal.;ArthritisRes.Ther.16,R38(2014)
- Identificationofadipokineclustersrelatedtoparametersoffatmass,insulinsensitivityandinflammation:G.Flehmig,etal.;PLoSOne9,e99785(2014)
- Extracellularnicotinamidephosphoribosyltransferase(NAMPT)promotesM2macrophagepolarizationinchroniclymphocyticleukemia:V.Audrito,etal.;Blood125,111(2015)
- Adipo/cytokinesinatheroscleroticsecretomes:increasedvisfatinlevelsinunstablecarotidplaque:T.Auguet,etal.;BMCCardiovas.Dis.16,149(2016)
- UmbilicalCordBloodandMaternalVisfatin(PBEF/Nampt)ConcentrationsinPretermBirthwithandwithoutPretermPrematureRuptureofMembranes:T.Pavlova,etal.;J.Matern.FetalNeonatalMed.aheadofprint(2017)
- CirculatingadipokinesandmRNAexpressioninadiposetissueandtheplacentainwomenwithgestationaldiabetesmellitus:P.C.Tsiotra,etal.;peptidesaheadofprint(2018)
品牌介绍
Adipogen公司由三个子公司组成，分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国，运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发，如癌症、免疫、炎症、代谢疾病（糖尿病、肥胖）、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外，也可提供抗体和蛋白产品，Adipogen拥有自己的化学实验室，致力于开发创新型小分子化合物。
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