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Adipogen/Complement C3 (human) ELISA Kit/YIF-LF-EK0177/1 x 96 wells
Adipogen/Complement C3 (human) ELISA Kit/YIF-LF-EK0177/1 x 96 wells
商品编号：
YIF-LF-EK0177
品牌：
Adipogen Inc
市场价：
¥12020.00
美元价：
7212.00
产品分类：
夹心法ELISA
公司分类：
Sandwich_method_ELISA
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| ProductDetails | |
|---|---|
| Synonyms | C3;CPAMD1 |
| ProductType | Kit |
| Properties | |
| ApplicationSet | CompoundScreening |
| Crossreactivity | Human |
| Quantity | 1x96wells |
| Sensitivity | 1.30ng/ml |
| AssayType | Sandwich |
| OtherProductData | ClickhereforOriginalManufacturerProductDatasheet Ourproductdescriptionmaydifferslightlyfromtheoriginalmanufacturersproductdatasheet. |
| Declaration | ManufacturedbyAbFrontier |
| ShippingandHandling | |
| Shipping | BLUEICE |
| ShortTermStorage | +4°C |
| LongTermStorage | +4°C |
| HandlingAdvice | Anyunusedreconstitutedstandardshouldbediscardedorfrozenat-80℃. Standardcanbefrozenandthawedonetimeonlywithoutlossofimmunoreactivity. |
| Documents | |
| Manual |  DownloadPDF |
| MSDS | No |
| ProductSpecificationSheet | |
| Datasheet | DownloadPDF |
HumanComplementC3(C3)issynthesizedasasingle-chainpro-molecule(185kDa)thatthensuffersseveralpost-translationalmodifications.Beforebeingsecretedasamatureprotein,C3issplitintoβ-chain(645residuesand70kDa)andα-chain(992residuesand115kDa)andformsarareinternalthioesterbond.C3playsacentralroleintheactivationofallthethreepathwaysofcomplementactivationi.e.theclassical,alternative,andlectinpathway.AsC3isthemajorcomplementcomponentandparticipatesinseveralstagesoftheimmuneresponse,itsdeficiencygenerallyassociatedwithhighersusceptibilitytoseverebacterialinfectionsandinsomecaseswithautoimmunediseasessuchassystemiclupuserythematosus.C3playsacentralroleintheactivationofthecomplementsystem.ItsprocessingbyC3convertaseisthecentralreactioninbothclassicalandalternativecomplementpathways.AfteractivationC3bcanbindcovalently,viaitsreactivethioester,tocellsurfacecarbohydratesorimmuneaggregates.DerivedfromproteolyticdegradationofcomplementC3,C3aanaphylatoxinisamediatoroflocalinflammatoryprocess.Itinducesthecontractionofsmoothmuscle,increasesvascularpermeABIlityandcauseshistaminereleasefrommastcellsandbasophilicleukocytes.
品牌介绍
Adipogen公司由三个子公司组成，分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国，运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发，如癌症、免疫、炎症、代谢疾病（糖尿病、肥胖）、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外，也可提供抗体和蛋白产品，Adipogen拥有自己的化学实验室，致力于开发创新型小分子化合物。
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