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当前位置: 首页 > 产品中心 > Sandwich_method_ELISA > Adipogen/8-OHdG Check ELISA Kit (High Sensitivity)/JAI-KOG-HS10E/1 Kit
商品详细Adipogen/8-OHdG Check ELISA Kit (High Sensitivity)/JAI-KOG-HS10E/1 Kit
Adipogen/8-OHdG Check ELISA Kit (High Sensitivity)/JAI-KOG-HS10E/1 Kit
Adipogen/8-OHdG Check ELISA Kit (High Sensitivity)/JAI-KOG-HS10E/1 Kit
商品编号: JAI-KOG-HS10E
品牌: Adipogen Inc
市场价: ¥17840.00
美元价: 10704.00
产地: 美国(厂家直采)
公司:
产品分类: 夹心法ELISA
公司分类: Sandwich_method_ELISA
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
MoreInformation
ProductDetails
Synonyms8-hydroxy-2"-deoxyguanosine
ProductTypeKit
Properties
ApplicationSetQuantitativeELISA
SpecificitySpecificfor8-OHdG.Hasbeentestedto8-OHdGanalogues(guanosine(G),7-methyl-G,6-SH-G,8-Bromo-G,dA,dC,dT,dI,dU,dG,O6-methyl-dG,8-OHdA,guanine(Gua),O6-methyl-Gua,8-OH-Gua,uricacid,urea,creatine,creatinine,8-sulfhydryl-G,8-OH-G).
CrossreactivityAll
Quantity96wells
Range0.125to10ng/mL
SampleTypePlasma
Serum
Urine
AssayTypeCompetitive
DetectionTypeColorimetric
OtherProductDataThisELISAKitsworksalsoforDNAextractedfromculturedcellsortissues.
DetectionGuideforSerum/Plasma
DetectionGuidefortissuesamplesorculturedcells
DeclarationManufacturedbyJaICA.
ShippingandHandling
ShippingBLUEICE
ShortTermStorage+4°C
LongTermStorage+4°C
HandlingAdviceDonotfreeze.
Use/StABIlity12monthsafterthedayofmanufacturing.SeeexpirydateonELISAKitbox.
Documents
ManualDownloadPDF
MSDSNo
ProductSpecificationSheet
DatasheetDownloadPDF
8-hydroxy-2"-deoxyguanosine(8-OHdG)isamodifiedbasethatoccursinDNAduetoattackbyhydroxylrADIcals(incl.singletoxygenanddirectphotodynamicaction)thatareformedasbyproductsandintermediatesofaerobicmetabolismandduringoxidativestress.Thereisincreasingevidencetosupporttheinvolvementoffreeradicalreactionsinthedamageofbiomoleculesthateventuallyleadtoseveraldiseasesinhumans,suchasatherosclerosis,cerebralandheartischemia-reperfusioninjury,cancer,rheumatoidarthritis,inflammation,diabetes,aging,andneurodegenerativeconditions,suchasAlzheimer’sdisease.8-OHdGispopularasasensitive,stableandintegralMarkerofoxidativedamageincellularDNAandcanbedetectedintissue,serum,urineandotherBiomaterials.
ProductReferences
  1. Quantitativedeterminationofurinary8-hydroxydeoxyguanosine(8-OH-dg)byusingELISA:S.Saito,etal.;Res.Commun.Mol.Pathol.Pharmacol.107,39(2000)[Developmentandassessmentof8-OHdGCheckELISA]
  2. DiscrepanciesinthemeasurementofUVC-induced8-oxo-2"-deoxyguanosine:ImplicationsfortheanalysisofoxidativeDNAdamage:M.D.Evans,etal.;BBRC259,374(1999)[HighcorrelationbetweenHPLC-ECDwhen8-OHdGinDNAsamples]
  3. Mutagenicityofreactiveoxygenandnitrogenspeciesasdetectedbyco-cultureofactivatedinflammatoryleukocytesandAS52cells:H.W.Kim,etal.;Carcinogenesis24,235(2003)[Detectionof8-OHdGinculturedcells]
  4. Significanceof8-hydroxy-2"-deoxyguanosinelevelsinpatientswithidiopathicdilatedcardiomyopathy:E.Watanabe,etal.;J.Card.Fail.12,527(2006)[Serum8-OHdGinIDCpatients]
  5. Acuteencephalopathywithrefractorystatusepilepticus:Bilateralmesialtemporalandclaustrallesions,associatedwithaperipheralmarkerofoxidativeDNAdamage:T.Shiihara,etal.;J.Neurol.Sci.250,159(2006)[Measurementof8-OHdGinhumanurine,serumandcerebrospinalfluid(CSF)]
  6. Effectsofcaloricrestrictiononpost-spawningdeathofayu:R.Nagasaka,etal.;Exp.Gerontol.40,556(2005)[Detectionof8-OHdGinfishtissues(brainandliver)]
  7. Salivary8-OHdG:ausefulbiomarkerforpredictingsevereEDandhypogonadism:M.Yasuda,etal.;J.Sex.Med.5,1482(2008)[Detectionof8-OHdGinsaliva]
品牌介绍
Adipogen公司由三个子公司组成,分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国,运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发,如癌症、免疫、炎症、代谢疾病(糖尿病、肥胖)、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外,也可提供抗体和蛋白产品,Adipogen拥有自己的化学实验室,致力于开发创新型小分子化合物。