Adipogen/Zerumbone/AG-CN2-0004-M050/50 mg
商品编号：
AG-CN2-0004-M050
品牌：
Adipogen Inc
市场价：
¥4400.00
美元价：
2640.00
产品分类：
其他试剂
公司分类：
Other_reagents
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| ProductDetails | |
|---|---|
| Synonyms | (2E,6E,10E)-2,6,9,9-Tetramethylcycloundeca-2,6,10-trien-1-one |
| ProductType | Chemical |
| Properties | |
| Formula | C15H22O |
| MW | 218.3 |
| CAS | 471-05-6 |
| Source/HostChemicals | IsolatedfromtheundergroundpartsofCurcumazerumbet. |
| PurityChemicals | ≥98%(HPLC) |
| Appearance | Solidwhitecrystalsorpowder. |
| Solubility | SolubleinDMSOor100%ethanol. |
| Identity | Determinedby1H-NMR. |
| OtherProductData | Preparationof1mMstocksolution:Dissolve0.218mgzerumbonein1mlsolvent. |
| InChiKey | GIHNTRQPEMKFKO-SKTNYSRSSA-N |
| ShippingandHandling | |
| Shipping | AMBIENT |
| ShortTermStorage | +4°C |
| LongTermStorage | -20°C |
| Use/StABIlity | Stableforatleast2yearsafterreceiptwhenstoredat-20°C. |
| Documents | |
| MSDS |  DownloadPDF |
| ProductSpecificationSheet | |
| Datasheet | DownloadPDF |
- Chemopreventiveprobe[1,2].
- Apoptosisinducer[3,4].
- Potentanti-tumorcompound[2-4].
- Anti-inflammatoryactivitybydownregulatingCOX-2andiNOSexpressionviamodulationofNF-κBactivation[5,6].
- Antinociceptive[7].
- Probetostudychemokinereceptorsfunctioning[8].
- Potentialtherapeuticagentforosteoporosisandcancer-associatedboneloss[9].
- Antidiabeticnephropathy[11]
ProductReferences
- Chemopreventionofazoxymethane-inducedrataberrantcryptfocibydietaryzerumboneisolatedfromZingiberzerumbet:T.Tanaka,etal.;LifeSci.69,1935(2001)
- ZerumboneenhancesTRAIL-inducedapoptosisthroughtheinductionofdeathreceptorsinhumancoloncancercells:Evidenceforanessentialroleofreactiveoxygenspecies.S.Yodkeeree,etal.;CancerRes.69,6581(2009)
- ZerumboneinducesapoptosisinT-acutelymphoblasticleukemiacells:S.I.ABDelwahab,etal.;Leuk.Res.35,268(2010)
- AntitumoreffectsofzerumbonefromZingiberzerumbetinP-388D1cellsinvitroandinvivo:G.C.Huang,etal.;PlantaMed.71,219(2005)
- Zerumbone,ananti-inflammatoryphytochemical,inducesexpressionofproinflammatorycytokinegenesinhumancolonadenocarcinomacelllines:A.Murakami,etal.;Biofactors21,95(2004)
- Anti-inflammatoryeffectofzerumboneonacuteandchronicinflammationmodelsinmice:M.R.Sulaiman,etal.;Fitoterapia81,855(2010)
- Preliminaryanalysisoftheantinociceptiveactivityofzerumbone:M.R.Sulaiman,etal.;Fitoterapia80,230(2009)
- Zerumbonedown-regulateschemokinereceptorCXCR4expressionleADIngtoinhibitionofCXCL12-inducedinvasionofbreastandpancreatictumorcells:B.Sung,etal.;CancerRes.68,8938(2008)
- ZerumboneabolishesRANKL-inducedNF-kappaBactivation,inhibitsosteoclastogenesis,andsuppresseshumanbreastcancer-inducedbonelossinathymicnudemice:B.Sung,etal.;CancerRes.69,1477(2009)
- ZerumboneabolishesNF-kappaBandIkappaBalphakinaseactivationleadingtosuppressionofantiapoptoticandmetastaticgeneexpression,upregulationofapoptosis,anddownregulationofinvasion:Y.Takada,etal.;Oncogene24,6957(2005)
- Zerumbone,atropicalgingersesquiterpene,amelioratesstreptozotocin-induceddiabeticnephropathyinratsbyreducingthehyperglycemia-inducedinflammatoryresponse:TF.Tzeng,etal.;Nutr.Metab.10,64(2013)
品牌介绍
Adipogen公司由三个子公司组成，分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国，运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发，如癌症、免疫、炎症、代谢疾病（糖尿病、肥胖）、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外，也可提供抗体和蛋白产品，Adipogen拥有自己的化学实验室，致力于开发创新型小分子化合物。
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