脂肪原/Z-Phe-Arg-AFC/AG-CP3-0028-M025/25毫克
商品编号：
AG-CP3-0028-M025
品牌：
Adipogen Inc
市场价：
¥4800.00
美元价：
2880.00
产品分类：
其他试剂
公司分类：
Other_reagents
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| ProductDetails | |
|---|---|
| Synonyms | Z-FR-AFC.TFA |
| ProductType | Chemical |
| Properties | |
| Formula | C33H33F3N6O6.C2HF3O2 |
| MW | 666.7.114.0 |
| Sequence | Z-Phe-Arg-7-amino-4-trifluoromethylcoumarin |
| CAS | 93753-73-2(freebase) |
| PurityChemicals | ≥95%(HPLC) |
| Appearance | Whitetooff-whitesolid. |
| Solubility | SolubleinDMSO.Moderatelysolubleandhighlystableinwater-basedsolvents. |
| InChiKey | FLPBOIDNDJASFK-CCQIZPNASA-N |
| ShippingandHandling | |
| Shipping | AMBIENT |
| ShortTermStorage | +4°C |
| LongTermStorage | -20°C |
| HandlingAdvice | Keepcoolanddry. |
| Use/StABIlity | Stableforatleast1yearafterreceiptwhenstoredat-20°C. |
| Documents | |
| MSDS | No |
| ProductSpecificationSheet | |
| Datasheet |  DownloadPDF |
- Fluorogenicsubstrate,specificallyusedtodeterminetheenzymeactivityofCathepsinL.
- UsefulforthestudyofcathepsinactivityandforscreeningsmallmoleculeinhibitorsfordrugdiscoveryandHTSapplications.LikelytobecleavedbycathepsinsB,F,K,SandL,cathepsinsL-likeproteasesandproteasessuchaspapain,cruzipain,plasmakallikrein,soybeantrypsin-likeenzymeandthefalcipains-1and-2(malariahemoglobinases).
- HydrolysisofthissubstrateismonitoredbyobservingfluorescenceatanExcitationof400nmandEmissionat505nm.
ProductReferences
- Newfluorogenicsubstratesforalpha-thrombin,factorXa,kallikreins,andurokinase:T.Morita,etal.;J.Biochem.82,1495(1977)
- Separationandidentificationofcathepsinsinnewbornratepidermis:R.J.Harvima,etal.;J.Invest.Dermatol.88,393(1987)
- Preliminarystudiesoncysteineandserineproteinaseactivitiesininflamedhumangingivausingdifferent7-amino-4-trifluoromethylcoumarinsubstratesandproteaseinhibitors:S.W.Cox&B.M.Eley;Arch.OralBiol.32,599(1987)
- PhotometricorfluorometricassayofcathepsinB,LandHandpapainusingsubstrateswithanaminotrifluoromethylcoumarinleavinggroup:J.R.Tchoupe,etal.;Biochim.Biophys.Acta1076,149(1991)
- DevelopmentallyregulatedsecretionofcathepsinL-likecysteineproteasesbyHaemonchuscontortus :M.L.Rhoads&R.H.Fetterer;J.Parasitol.81,505(1995)
- TaeniasaginataOncosphereExcretory/SecretoryPeptidases:A.ClintonWhite,Jr. ;J.Parasitol.82,7(1996)
- HumancathepsinF:expressioninbaculovirussystem,characterizationandinhibitionbyproteininhibitors:M.Fonovic,etal.;Biol.Chem.385,505(2004)
- Identificationandbiochemicalcharacterizationofvivapains,cysteineproteasesofthemalariaparasitePlasmodiumvivax :B.-K.NA,etal.;Biochem.J.378,529(2004)
- Crosstalkbetweentheubiquitin-proteasomesystemandautophagyinahumancellularmodelofAlzheimer"sdisease:V.Cecarini,etal.;Biochim.Biophys.Acta1822,1741(2012)
- CysteineProteaseInhibitor(ACSTefin)IsRequiredforCompleteCystFormationofAcanthamoeba:J-Y.Lee,etal.;Eukaryot.Cell12,567(2013)
- Phospholambanoverexpressioninmicecausesacentronuclearmyopathy-likephenotype:V.A.Fajardo,etal.;Dis.ModelMech.8,999(2015)
- Dataonskeletalmuscleapoptosis,autophagy,andmorphologyinmicetreatedwithdoxorubicin:T.L.Campbell,etal.;DataBrief7,786(2016)
- Sarcolipindeletionexacerbatessoleusmuscleatrophyandweaknessinphospholambanoverexpressingmice:V.A.Fajardo,etal.;PLoSOne12,e0173708(2017)
品牌介绍
Adipogen公司由三个子公司组成，分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国，运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发，如癌症、免疫、炎症、代谢疾病（糖尿病、肥胖）、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外，也可提供抗体和蛋白产品，Adipogen拥有自己的化学实验室，致力于开发创新型小分子化合物。
联络我们
