![Adipogen/Z-Leu-Leu-Nva-CHO [MG-115]/AG-CP3-0015-M001/1 mg](https://www.ebiomall.cn/images/adipogen/ag-cp3-0015_mg-115.png)
Adipogen/Z-Leu-Leu-Nva-CHO [MG-115]/AG-CP3-0015-M001/1 mg
商品编号：
AG-CP3-0015-M001
品牌：
Adipogen Inc
市场价：
¥400.00
美元价：
240.00
产品分类：
其他试剂
公司分类：
Other_reagents
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| Product Details | |
|---|---|
| Synonyms | Z-LLNva-CHO; Proteasome Inhibitor |
| Product Type | Chemical |
| Properties | |
| Formula | C25H39N3O5 |
| MW | 461.6 |
| Sequence | Z-Leu-Leu-Nva-aldehyde |
| CAS | 133407-86-0 |
| Purity Chemicals | ≥95% (HPLC) |
| Appearance | Solid lyophilized powder. |
| Solubility | Soluble in DMSO. |
| Other Product Data | Use: Add from DMSO stock directly to in vitro or in vivo assays at desired concentration. Pre-incubation with compound prior to assay is recommended for maximal effect. |
| InChi Key | QEJRGURBLQWEOU-FKBYEOEOSA-N |
| Shipping and Handling | |
| Shipping | AMBIENT |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Handling Advice | Keep cool and dry. |
| Use/Stability | Stable for at least 2 years after receipt when stored at -20°C. |
| Documents | |
| MSDS |
 Download PDF |
| Product Specification Sheet | |
| Datasheet |
Download PDF |
- Potent, reversible and cell permeable proteasome inhibitor. Specifically inhibits the chymotrypsin-like activity of the proteasome.
- Calpain and cathepsin inhibitor.
- Apoptosis inducer in Rat-1 and PC12 cells via a p53-dependent pathway.
- Autophagy activator.
Product References
- Potent and selective inhibitors of the proteasome: dipeptidyl boronic acids: J. Adams, et al.; Bioorg. Med. Chem. Lett. 17, 333 (1998)
- Ubiquitination of E3 ubiquitin ligase TRIM5 alpha and its potential role: K. Yamauchi, et al.; FEBS J. 275, 1540 (2008)
- Proteasome inhibition induces stress kinase dependent transport deficits-implications for Alzheimer's disease: L. Agholme, et al.; Mol. Cell Neurosci. 58, 29 (2014)
品牌介绍
Adipogen公司由三个子公司组成，分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国，运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发，如癌症、免疫、炎症、代谢疾病（糖尿病、肥胖）、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外，也可提供抗体和蛋白产品，Adipogen拥有自己的化学实验室，致力于开发创新型小分子化合物。
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