![Adipogen/Z-Leu-Leu-Leu-B(OH)2 [MG-262]/AG-CP3-0024-M001/1 mg](https://www.ebiomall.cn/images/adipogen/ag-cp3-0024_mg-262.png)
Adipogen/Z-Leu-Leu-Leu-B(OH)2 [MG-262]/AG-CP3-0024-M001/1 mg
商品编号：
AG-CP3-0024-M001
品牌：
Adipogen Inc
市场价：
¥18600.00
美元价：
11160.00
产品分类：
其他试剂
公司分类：
Other_reagents
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| ProductDetails | |
|---|---|
| Synonyms | Z-LLL-B(OH)2;ProteasomeInhibitorIII |
| ProductType | Chemical |
| Properties | |
| Formula | C25H42BN3O6 |
| MW | 491.4 |
| Sequence | Z-Leu-Leu-Leu-B(OH)2 |
| CAS | 179324-22-2 |
| PurityChemicals | ≥95%(HPLC) |
| Appearance | Solidlyophilizedpowder. |
| Solubility | SolubleinDMSO. |
| InChiKey | MWKOOGAFELWOCD-FKBYEOEOSA-N |
| ShippingandHandling | |
| Shipping | BLUEICE |
| ShortTermStorage | +4°C |
| LongTermStorage | -20°C |
| HandlingAdvice | Avoidfreeze/thawcycles. |
| Use/StABIlity | Stableforatleast1yearafterreceiptwhenstoredat-20°C. |
| Documents | |
| MSDS |  DownloadPDF |
| ProductSpecificationSheet | |
| Datasheet | DownloadPDF |
- Highlypotentandselectivecellpermeableinhibitoroftheproteasome.Inhibitsthechymotrypsin-likeandcaspase-likepeptidaseactivityoftheproteasome.
- Calpainandcathepsininhibitor.
- Autophagyactivator.
- SimilarstructureasMG-132(AG-CP3-0011)butmuchhigherpotency.
ProductReferences
- Down-regulationofFlt-1geneexpressionbytheproteasomeinhibitorMG262:J.Mezquita,etal.;J.Cell.Biochem.89,1138(2003)
- Importanceofthedifferentproteolyticsitesoftheproteasomeandtheefficacyofinhibitorsvarieswiththeproteinsubstrate:A.F.Kisselev,etal.;J.Biol.Chem.281,8582(2006)
- IdentificationoftheproteasomeinhibitorMG262asapotentATP-dependentinhibitoroftheSalmonellaentericaSEROvarTyphimuriumLonprotease:H.Frase,etal.;Biochemistry45,8264(2006)
- CharacterizationofthePhysiologicalTurnoverofNativeandInactivatedCytochromesP4503AinCulturedRatHepatocytes:ARolefortheCytosolicAAAATPasep97?:S.Faouzi,etal.;Biochemistry46,7793(2007)
- Proteasomeactivityandautophagosomecontentinliverarereciprocallyregulatedbyethanoltreatment:P.G.Thomes,etal.;BBRC417,262(2012)
品牌介绍
Adipogen公司由三个子公司组成，分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国，运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发，如癌症、免疫、炎症、代谢疾病（糖尿病、肥胖）、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外，也可提供抗体和蛋白产品，Adipogen拥有自己的化学实验室，致力于开发创新型小分子化合物。
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