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当前位置: 首页 > 产品中心 > Other_reagents > Adipogen/Xanthorrhizol/AG-CN2-0090-M001/1 mg
商品详细Adipogen/Xanthorrhizol/AG-CN2-0090-M001/1 mg
Adipogen/Xanthorrhizol/AG-CN2-0090-M001/1 mg
Adipogen/Xanthorrhizol/AG-CN2-0090-M001/1 mg
商品编号: AG-CN2-0090-M001
品牌: Adipogen Inc
市场价: ¥3000.00
美元价: 1800.00
产地: 美国(厂家直采)
公司:
产品分类: 其他试剂
公司分类: Other_reagents
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
MoreInformation
ProductDetails
Synonyms1,3,5,10-Bisabolatetraen-2-ol
ProductTypeChemical
Properties
FormulaC15H22O
MW218.3
CAS30199-26-9
Source/HostChemicalsIsolatedfromCurcumaxanthorrhiza.
PurityChemicals≥97%(NMR)
AppearanceColorlesstolightyellowoil.
SolubilitySolubleinDMSOorethanol.
IdentityDeterminedby1H-NMR,13C-NMRandMS.
InChiKeyFKWGCEDRLNNZOZ-GFCCVEGCSA-N
ShippingandHandling
ShippingAMBIENT
ShortTermStorage+4°C
LongTermStorage-20°C
HandlingAdviceKeepcoolanddry.
Protectfromlight.
Use/StABIlityStableforatleast2yearsafterreceiptwhenstoredat-20°C.
Documents
MSDSDownloadPDF
ProductSpecificationSheet
DatasheetDownloadPDF
  • Showscalcium-antagoNISTicandvasorelaxantactivity[1,3].
  • Antibacterial[2].
  • Anti-inflammatory.PotentCOX-2andinducIBLenitricoxide(iNOS;NOSII)inhibitor[4,5,9].
  • Hepatoprotective[5,6].
  • Anticancercompound.Apoptosisinducer[7,8,10,12].
  • Neuroprotectiveantioxidant[8].
  • Antifungal[11].
ProductReferences
  1. Effectofxanthorrhizol,xanthorrhizolglycosideandtrachylobanoicacidisolatedfromCachanicomplexplantsuponthecontractileactivityofuterinesmoothmuscle:H.Ponce-Monter,etal.;Phytother.Res.13,202(1999)
  2. AntibacterialactivityofxanthorrhizolfromCurcumaxanthorrhizaagainstoralpathogens:J.K.Hwang,etal.;Fitoterapia71,321(2000)
  3. Xanthorrhizolinducesendothelium-independentrelaxationofratthoracicaorta:M.G.Campos,etal.;LifeSci.67,327(2000)
  4. Suppressiveeffectofnaturalsesquiterpenoidsoninduciblecyclooxygenase(COX-2)andnitricoxidesynthase(iNOS)activityinmousemacrophagecells:S.K.Lee,etal.;J.Environ.Pathol.Toxicol.Oncol.21,141(2002)
  5. Abrogationofcisplatin-inducedhepatotoxicityinmicebyxanthorrhizolisrelatedtoitseffectontheregulationofgenetranscription:S.H.Kim,etal.;Toxicol.Appl.Pharmacol.196,346(2004)
  6. Phosphorylationofc-JunN-terminalKinases(JNKs)isinvolvedinthepreventiveeffectofxanthorrhizoloncisplatin-inducedhepatotoxicity:K.O.Hong,etal.;Arch.Toxicol.79,231(2005)
  7. Xanthorrhizolinducesapoptosisviatheup-regulationofbaxandp53inHeLacells:N.Ismail,etal.;AnticancerRes.25,2221(2005)
  8. Antioxidantandantiinflammatoryactivitiesofxanthorrhizolinhippocampalneuronsandprimaryculturedmicroglia:C.S.Lim,etal.;J.Neurosci.Res.82,831(2005)
  9. Regulationofp53-,Bcl-2-andcaspase-dependentsignalingpathwayinxanthorrhizol-inducedapoptosisofHepG2hepatomacells:T.Handayani,etal.;AnticancerRes.27,965(2007)
  10. Xanthorrhizolinhibits12-O-tetradecanoylphorbol-13-acetate-inducedacuteinflammationandtwo-stagemouseskincarcinogenesisbyblockingtheexpressionofornithinedecarboxylase,cyclooxygenase-2andinduciblenitricoxidesynthasethroughmitogen-acti:W.Y.Chung,etal.;Carcinogenesis28,1224(2007)
  11. InVitroantimycoticactivityofxanthorrhizolisolatedfromCurcumaxanthorrhizaRoxb.againstopportunisticfilamentousfungi:Y.RukayADI&J.K.Hwang;Phytother.Res.21,434(2007)
  12. Regulationofp53-,Bcl-2-andcaspase-dependentsignalingpathwayinXanthorrhizolinducedDNAfragmentationinHepG2cellsinvolvingBcl-2familyproteins:BBRC420,834(2012)
品牌介绍
Adipogen公司由三个子公司组成,分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国,运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发,如癌症、免疫、炎症、代谢疾病(糖尿病、肥胖)、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外,也可提供抗体和蛋白产品,Adipogen拥有自己的化学实验室,致力于开发创新型小分子化合物。