Adipogen/Verruculogen/BVT-0443-M001/1 mg
商品编号：
BVT-0443-M001
品牌：
Adipogen Inc
市场价：
¥1600.00
美元价：
960.00
产品分类：
其他试剂
公司分类：
Other_reagents
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| ProductDetails | |
|---|---|
| Synonyms | NA209A;TR1 |
| ProductType | Chemical |
| Properties | |
| Formula | C27H33N3O7 |
| MW | 511.6 |
| CAS | 12771-72-1 |
| RTECS | JH4920000 |
| Source/HostChemicals | IsolatedfromAspergillusfumigatus. |
| PurityChemicals | ≥98%(HPLC) |
| Appearance | Whitetooff-whitesolid. |
| Solubility | SolubleinDMSO,100%ethanol,methanolordichloromethane. |
| Identity | Determinedby1H-NMRandMS. |
| Declaration | ManufacturedbyBioViotica. |
| InChiKey | LRXYHMMJJCTUMY-GWXUGYLUSA-N |
| ShippingandHandling | |
| Shipping | AMBIENT |
| ShortTermStorage | +4°C |
| LongTermStorage | -20°C |
| HandlingAdvice | Protectfromlightwheninsolution. |
| Use/StABIlity | Stableforatleast2yearsafterreceiptwhenstoredat-20°C. Storesolutionsat-20°Cinthedark. |
| Documents | |
| MSDS |  DownloadPDF |
| ProductSpecificationSheet | |
| Datasheet | DownloadPDF |
- Fumitremorgin-typealkaloid.
- Tremorgenicneurotoxicmycotoxin.
- SelectiveblockerofKCa1.1(high-conductanceCa2+-activatedK+;BK;maxi-K)channels.
- DecreasesGABAlevelsinCNS.
- Increasesspontaneousglutamateandaspartaterelease.
- Attoxicdoses,increasesthenumberanddecreasestheaffinityofDHPreceptorsinratcortex.
- CellcycleinhibitorattheMphase.
- InhibitscalmodulinandPKCactivity.
- HasapoptoticeffectsonhumanTlymphocytes.
- Stimulatesthegrowthofseedlingrootsofbuckwheat.
ProductReferences
- TremorgenictoxinfromPenicilliumveruculosum:R.J.Cole,etal.;Appl.Microbiol.24,248(1972)
- Thestructureofverruculogen.AtremorproducingepoxidefromPenicilliumerruculosum:J.Fayos,etal.;JACS96,6785(1974)
- Verruculogen:anewsubstancefordecreasingofGABAlevelsinCNS:L.Hotujac,etal.;Pharmacol.14,297(1976)
- Actionsoftremorgenicfungaltoxinsonneurotransmitterrelease:P.J.Norris,etal.;J.NeuRochem.34,33(1980)
- Actionsofatremorgenicmycotoxinonaminoacidtransmitterreleaseinvivo:D.W.Peterson,etal.;Biochem.Pharmacol.31,2807(1982)
- Invitroeffectsoftremorgenicmycotoxins:M.I.Selala,etal.;J.Nat.Prod.54,207(1991)
- Tremorgenicindolealkaloidspotentlyinhibitsmoothmusclehigh-conductancecalcium-activatedpotassiumchannels:H.H.Knaus,etal.;Biochemistry33,5819(1994)
- Behavioralandbiochemicaleffectsofthetremorgenicmycotoxinverruculogen:L.Intorre,etal.;Environ.Toxicol.Chem.46,119(1994)
- Novelmammaliancellcycleinhibitors,tryprostatinsA,BandotherdiketopiperazinesproducedbyAspergillusfumigatus.II.Physico-chemicalpropertiesandstructures:C.B.Cui,etal.;J.Antibiot.49,534(1996)
- Totalsynthesisoffumitremorginsandverruculogens:T.Hino&M.Nakagawa;Heterocycles46,673(1997)
- ModulationofcalmodulinandproteinkinaseCactivitiesbyPenicilliummycotoxins:I.Pala,etal.;Int.J.Toxicol.18,91(1999)
- Genotoxicityassessmentoffivetremorgenicmycotoxins(fumitremorgenB,paxilline,penitremA,verruculogenandverrucosidin)producedbymoldsisolatedfromfermentedmeats:M.Sabater-Vilar,etal.;J.FoodProtect.66,2123(2003)
- Influencealkaloidsfromthemarine-derivedstrainofthefungusAspergillusfumigatusFresen.onthegrowthofseedlingrootsofbuckwheat(FagopyrumesculentumMoench):M.Anisimov,etal.;Int.J.Res.Rev.Appl.Sci.13,326(2012)
- AspergillusfumigatustoxinscausecytotoxicandapoptoticeffectsonhumanTlymphocytes(Jurkatcells):H.Malekinejad,etal.;WorldMycotoxin6,65(2013)
品牌介绍
Adipogen公司由三个子公司组成，分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国，运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发，如癌症、免疫、炎症、代谢疾病（糖尿病、肥胖）、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外，也可提供抗体和蛋白产品，Adipogen拥有自己的化学实验室，致力于开发创新型小分子化合物。
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