Adipogen/Varenicline tartrate/SYN-3013-M010/10 mg
商品编号：
SYN-3013-M010
品牌：
Adipogen Inc
市场价：
¥3680.00
美元价：
2208.00
产品分类：
其他试剂
公司分类：
Other_reagents
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| ProductDetails | |
|---|---|
| Synonyms | Chantix;Champix |
| ProductType | Chemical |
| Properties | |
| Formula | C13H13N3.C4H6O6 |
| MW | 211.3.150.1 |
| CAS | 375815-87-5 |
| PurityChemicals | ≥95% |
| Appearance | Solid. |
| Solubility | SolubleinDMSOorethanol. |
| Declaration | ManufacturedbySynKinase. |
| OtherProductData | Target:NicotinicAChreceptor|KinaseGroup:N/A|Substrate:N/A ClickhereforOriginalManufacturerProductDatasheet Ourproductdescriptionmaydifferslightlyfromtheoriginalmanufacturersproductdatasheet. |
| InChiKey | TWYFGYXQSYOKLK-CYUSMAIQSA-N |
| ShippingandHandling | |
| Shipping | AMBIENT |
| ShortTermStorage | +4°C |
| LongTermStorage | -20°C |
| Use/StABIlity | Stableforatleast2yearsafterreceiptwhenstoredat-20°C. |
| Documents | |
| MSDS | No |
| ProductSpecificationSheet | |
| Datasheet |  DownloadPDF |
Vareniclineisaprescriptionmedicationusedtotreatsmokingaddiction.Itisapartialagonistoftheα4/β2subtypeofthenicotinicacetylcholinereceptor.Inaddition,itactsonα3/β4andweaklyonα3β2andα6-containingreceptors.Afullagonismwasdisplayedonα7-receptors.Itstimulatesnicotinereceptorsweakerthannicotineandissimilartocytisineinthisrespectanddifferenttothenicotinicantagonistbupropion.InvitrostudiesdemonstratedthatvareniclinedoesnotinhibitthecytochromeP450enzymes(IC50>6400ng/mL):1A2,2A6,2B6,2C8,2C9,2C19,2D6,2E1,and3A4/5.Inhumanhepatocytesinvitro,vareniclinedoesnotinducethecytochromeP450enzymes1A2and3A4.
ProductReferences
- Varenicline:analpha4beta2nicotinicreceptorpartialagoNISTforsmokingcessation:J.W.Coe,etal.;J.Med.Chem.48,3474(2005)
- Pharmacologicalprofileofthealpha4beta2nicotinicacetylcholinereceptorpartialagonistvarenicline,aneffectivesmokingcessationaid:H.Rollema,etal.;Neuropharmacol.52,985(2007)
品牌介绍
Adipogen公司由三个子公司组成，分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国，运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发，如癌症、免疫、炎症、代谢疾病（糖尿病、肥胖）、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外，也可提供抗体和蛋白产品，Adipogen拥有自己的化学实验室，致力于开发创新型小分子化合物。
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