脂肪原/伞形酮/AG-CN2-0085-M010/10毫克
商品编号：
AG-CN2-0085-M010
品牌：
Adipogen Inc
市场价：
¥2400.00
美元价：
1440.00
产品分类：
其他试剂
公司分类：
Other_reagents
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| Product Details | |
|---|---|
| Synonyms | (-)-Umbellulone; Umbellol; NSC 22046; BRN 2042730; Oreodaphnol; 3-Thujen-2-one |
| Product Type | Chemical |
| Properties | |
| Formula |
C10H14O |
| MW | 150.2 |
| CAS | 546-78-1 |
| RTECS | XP0200000 |
| Source/Host Chemicals | Isolated from Umbellularia californica Nutt. |
| Purity Chemicals | ≥98% (HPLC) |
| Appearance | Colourless oil. |
| Solubility | Soluble in DMSO or ethanol. |
| Identity | Determined by 1H-NMR. |
| Other Product Data |
Irritant: Umbellulone is a headache-inducing monoterpene ketone. Can induce headache when inhaling. Caution should be taken when dealing with this substance. |
| InChi Key | LTTVJAQLCIHAFV-UHFFFAOYSA-N |
| Shipping and Handling | |
| Shipping | AMBIENT |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Handling Advice | Keep cool and dry. |
| Use/Stability | Stable for at least 2 years after receipt when stored at -20°C. |
| Documents | |
| MSDS |
 Download PDF |
| Product Specification Sheet | |
| Datasheet |
Download PDF |
- Offensive principle of the so-called "headache tree".
- Causes a painful cold sensation.
- Selective TRPA1 activator. Weak TRPM8 activator.
- Releases CGRP (calcitonin gene-related peptide) after TRPA1 activation which leads to activation of trigeminovascular pathways and CGRP-mediated neurogenic vasodilatation relevant to produce headache/migraine.
Product References
- Umbellulone modulates TRP channels: J. Zhong, et al.; Pflugers Arch. 462, 861 (2011)
- The 'headache tree' via umbellulone and TRPA1 activates the trigeminovascular system: R. Nassini, et al.; Brain 135, 376 (2012)
- Activation of TRPA1 on dural afferents: a potential mechanism of headache pain: R.M. Edelmayer, et al.; Pain 153, 1949 (2012)
品牌介绍
Adipogen公司由三个子公司组成，分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国，运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发，如癌症、免疫、炎症、代谢疾病（糖尿病、肥胖）、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外，也可提供抗体和蛋白产品，Adipogen拥有自己的化学实验室，致力于开发创新型小分子化合物。
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