Adipogen/Trolox/AG-CR1-3639-G001/1 g
商品编号：
AG-CR1-3639-G001
品牌：
Adipogen Inc
市场价：
¥1100.00
美元价：
660.00
产品分类：
其他试剂
公司分类：
Other_reagents
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| ProductDetails | |
|---|---|
| Synonyms | (±)-6-Hydroxy-2,5,7,8-tetramethylchromane-2-carboxylicacid;TroloxC |
| ProductType | Chemical |
| Properties | |
| Formula | C14H18O4 |
| MW | 250.3 |
| CAS | 53188-07-1 |
| RTECS | DJ2273000 |
| PurityChemicals | ≥98%(HPLC) |
| Appearance | Whitetooff-whiteorpaleyellowsolid. |
| Solubility | SolubleinDMSO(20mg/ml),100%ethanol(20mg/ml)ormethanol(5mg/ml).Slightlysolubleinwater(~1mg/ml)andPBS(3mg/ml). |
| InChiKey | GLEVLJDDWXEYCO-UHFFFAOYSA-N |
| ShippingandHandling | |
| Shipping | AMBIENT |
| ShortTermStorage | +20°C |
| LongTermStorage | +4°C |
| HandlingAdvice | Keepcoolanddry. Protectfrommoistureandoxygen. |
| Use/StABIlity | Stableforatleast2yearsafterreceiptwhenstoredat+4°C. |
| Documents | |
| MSDS |  DownloadPDF |
| ProductSpecificationSheet | |
| Datasheet | DownloadPDF |
- CellpermeableandwatersolublederivativeofvitaminE.
- Potentantioxidant.Efficientlypreventsformationofdifferentreactiveoxygenspecies,suchassingletoxygen(1O2),superoxideanion(O2-)orhydrogenperoxide(H2O2).
- Commonlyusedasastandardorpositivecontrolindifferentantioxidantassays,suchasABTSdecolorizationandFRAPassays,measuringTroloxequivalentantioxidantcapacity(TEAC).TEACassaysareusedtomeasureantioxidantcapacityoffoods,beveragesandsupplements.
- UsedinBIOLOGicalorbiochemicalapplicationstoreduceoxidativestressordamage,suchasinhibitingperoxynitritemediatedtyrosinenitrationandmitochondrialprotonpermeability.
- Cytoprotectivewithlowcytotoxicityfordifferentcelllines.Showntohaveanticanceractivityandtobeeffectiveasadjunctiveagentincancertreatments.
- Usedtoreducefluorophorebleachingaswellasthefluorophoreblinkingduringtheobservationoffluorescentlabels.
- Freezingextendersupplementincryopreservationmediatoimprovethequalityofcryopreservedhumansperm.
ProductReferences
- ThecytoprotectiveeffectofTroloxdemonstratedwiththreetypesofhumancells:T.W.Wu,etal.;Biochem.CellBiol.68,1189(1990)
- Oxidativestress-inducedapoptosispreventedbyTrolox:V.J.Forrest,etal.;FreeRADIc.Biol.Med.16,675(1994)
- Troloxinhibitsperoxynitrite-mediatedoxidativestressandapoptosisinratthymocytes:M.G.Salgo&W.A.Pryor;Arch.Biochem.Biophys.333,482(1996)
- AntioxidantactivityapplyinganimprovedABTSradicalcationdecolorizationassay:R.Re,etal.;FreeRadicalBiol.Med.26,1231(1999)
- Comparativestudyofeightwell-knownpolyphenolicantioxidants:P.Cos,etal.;J.Pharm.Pharmacol.55,1291(2003)
- Freeradicalscavengerandantioxidantcapacitycorrelationofalpha-tocopherolandTroloxmeasuredbythreeinvitromethodologies:I.A.Castro,etal.;Int.J.FoodSci.Nutr.57,75(2006)
- Nonblinkingandlong-lastingsingle-moleculefluorescenceimaging:I.Rasnik,etal.;Nat.Methods3,891(2006)
- Troloxenhancestheanti-lymphomaeffectsofarsenictrioxide,whileprotectingagainstlivertoxicity:Z.Diaz,etal.;Leukemia21,2117(2007)
- TaxolinducesoxidativeneuronalcelldeathbyenhancingtheactivityofNADPHoxidaseinmousecorticalcultures:H.J.Jang,etal.;Neurosci.Lett.443,17(2008)
- CompoundsthatconferthermalstressresistanceandextendedLifespan:M.G.Benedetti,etal.;Exp.Gerontol.43,882(2008)
- TheantioxidantTroloxrestoresmitochondrialmembranepotentialandCa2+-stimulatedATPproductioninhumancomplexIdeficiency:F.Distelmaier,etal.;J.Mol.Med.87,515(2009)
- TroloxpreventsosteoclastogenesisbysuppressingRANKLexpressionandsignalling:J.H.Lee,etal.;J.Biol.Chem.284,13725(2009)
- OnthemechanismofTroloxasantIBLinkingandantibleachingreagent:T.Cordes,etal.;JACS131,5018(2009)
- InhibitoryeffectofTroloxonthemigrationandinvasionofhumanlungandcervicalcancercells:H.J.Sung,etal.;Int.J.Mol.Med.29,245(2012)
- EffectofTroloxadditiontocryopreservationmediaonhumanspermmotility:M.B.Minaei,etal.;Iran.J.Reprod.Med.10,99(2012)
- AphysicochemicalexaminationofthefreeradicalscavengingactivityofTrolox:mechanism,kineticsandinfluenceoftheenvironment:M.E.Alberto,etal.;Phys.Chem.Chem.Phys.15,4642(2013)
- EffectsofmolecularstructureonkineticsanddynamicsofthetroloxequivalentantioxidantcapacityassaywithABTS(+•):X.Tian&K.M.Schaich;J.Agric.FoodChem.61,5511(2013)
品牌介绍
Adipogen公司由三个子公司组成，分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国，运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发，如癌症、免疫、炎症、代谢疾病（糖尿病、肥胖）、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外，也可提供抗体和蛋白产品，Adipogen拥有自己的化学实验室，致力于开发创新型小分子化合物。
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