| Product Details | |
|---|---|
| Synonyms | 2-Amino-2-(hydroxymethyl)-1,3-propanediol; THAM; Tris base; Trometamol |
| Product Type | Chemical |
| Properties | |
| Formula | C4H11NO3 |
| MW | 121.14 |
| CAS | 77-86-1 |
| Source/Host Chemicals | Synthetic. |
| Purity Chemicals | ≥99% |
| Appearance | White to off-white powder. |
| Solubility | Soluble in water (550mg/ml), methanol (26mg/ml), ethanol (14mg/ml), DMF (14mg/ml) or acetone (2mg/ml). |
| Identity | Determined by 1H-NMR. |
| Declaration | Manufactured by Chemodex. |
| Other Product Data |
Click here for Original Manufacturer Product Datasheet Our product description may differ slightly from the original manufacturers product datasheet. |
| InChi Key | LENZDBCJOHFCAS-UHFFFAOYSA-N |
| Shipping and Handling | |
| Shipping | AMBIENT |
| Short Term Storage | +20°C |
| Long Term Storage | +20°C |
| Handling Advice | Protect from moisture. |
| Use/Stability | Stable for at least 2 years after receipt when stored at RT. |
| Documents | |
| MSDS | No |
| Product Specification Sheet | |
| Datasheet |
 Download PDF |
A high quality buffer used in the range of physiological pH 7-9. Widely used as a biological buffer or as a component of buffer formulations. Tris has a pKa of 8.06 and is very useful in the biology and biochemistry lab because it has buffering capabilities in the range of the typical physiological pH of most living organisms (pH 7.0-9.0). Tris has been reported to interfere with the activity of a number of enzymes, it should therefore be used carefully when studying proteins.
(1) R.H. Kallet, et al.; Am. J. Respir. Crit. Care Med. 161, 1149 (2000) | (2) W.T. Desmarais, et al.; Structure 10, 1063 (2002) | (3) Z. Ghalanbor, et al.; Protein Pept. Lett. 15, 212 (2008) | (4) J. Sambrook, & D.W. Russell; Molecular Cloning: A Laboratory Manual (2012)
