| ProductDetails | |
|---|---|
| Synonyms | (E)-2-DecenoicAcid;trans-2-DecylenicAcid;StreptococcusDiffusIBLeSignalFactor;SDSF |
| ProductType | Chemical |
| Properties | |
| Formula | C10H18O2 |
| MW | 170.25 |
| CAS | 334-49-6 |
| Source/HostChemicals | Synthetic. |
| PurityChemicals | ≥95%(NMR) |
| Appearance | Viscousoil. |
| Solubility | SolubleinDMSO,DMF(both30mg/ml)orethanol(20mg/ml). |
| Identity | Determinedby1H-NMR. |
| Declaration | ManufacturedbyChemodex. |
| OtherProductData | ClickhereforOriginalManufacturerProductDatasheet |
| InChiKey | WXBXVVIUZANZAU-CMDGGOBGSA-N |
| ShippingandHandling | |
| Shipping | AMBIENT |
| ShortTermStorage | +4°C |
| LongTermStorage | -20°C |
| HandlingAdvice | Protectfromlightandmoisture. |
| Use/StABIlity | Stableforatleast2yearsafterreceiptwhenstoredat-20°C. |
| Documents | |
| MSDS | No |
| ProductSpecificationSheet | |
| Datasheet |  DownloadPDF |
trans-2-DecenoicacidisanunsaturatedshortchainfattyacidthatissecretedbyS.mutans.Itisanovelinterkingdom-signalingmolecule(fromaGram-positiveorganism)thatinhibitshyphalformationofthedimorphicfungusC.albicansbyblockingtheyeast-to-hyphalmorphologicaltransition.Itmightplayacriticalroleinregulatingthedisintegrationofaerobicgranules.Asinotherpartsofthebody,StreptococciandCandidacoexistinthemouthandcompeteforthesamesubstrate.InamixedspeciesenvironmentsuchastheoralcavitythequantitativeandqualitativenatureofthebacteriamodulatesthebiofilmformationofC.albicans.trans-2-Decenoicacidisstructurallysimilartoundecylenicacid,theactiveingredientofDesenex,awidelyusedantifungalagent.Inaddition,trans-2-DecenoicacidinhibitedtheluciferasereporteractivityandthereforethebioluminescenceoftheGram-negativemarinebacteriaVibrioharveyi.trans-2-Decenoicacidisfoundinroyaljellyproducedfromthehypopharyngealandmandibularglandsecretionsofhoneybees.Demonstratesweakestrogenicactivity,inhibitingbindingof17β-estrADIoltoestrogenreceptorβ.
(1)K.M.Suzuki,etal.;Evid.BasedComplement.Alternat.Med.5,295(2008)|(2)D.G.Davies&C.N.H.Marques;J.Bateriol.191,1393(2009)|(3)R.Vilchez,etal.;ChemBioChem11,1552(2010)|(4)P.-J.Cai,etal.;Biores.Technol.182,823(2013)
