![脂肪原/脂肪酸/脂肪酸/脂肪酸[脂肪酸/脂肪酸]/SBB-PS0010-M002/2 mg](https://www.ebiomall.cn/images/adipogen/sbb-ps0010.png)
脂肪原/脂肪酸/脂肪酸/脂肪酸[脂肪酸/脂肪酸]/SBB-PS0010-M002/2 mg
商品编号：
SBB-PS0010-M002
品牌：
Adipogen Inc
市场价：
¥1220.00
美元价：
732.00
产品分类：
其他试剂
公司分类：
Other_reagents
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| ProductDetails | |
|---|---|
| Synonyms | ProteasomeSubstrate |
| ProductType | Chemical |
| Properties | |
| Formula | C40H53N5O10 |
| MW | 763.9 |
| Sequence | N-Succinyl-Leu-Leu-Val-Tyr-7-amido-4-methylcoumarin |
| CAS | 94367-21-2 |
| PurityChemicals | ≥99%(HPLC) |
| Appearance | Lyophilizedpowder. |
| Solubility | SolubleinDMSO. |
| Declaration | ManufacturedbySouthBayBio. |
| OtherProductData | Use:AfterpreparingastocksolutioninDMSO(≥10mM)storeproductat-20°Cto-80°C.Itisrecommendedtomakemultiplealiquotsafterthefirstthawtoensurebestperformance.Chymotrypsin-likeactivitycanbemeasuredusingatypicalworkingconcentrationrangefrom10-50µM.ClickhereforaTypicalLot-specificProductDatasheetfromtheOriginalManufacturer Ourproductdescriptionmaydifferslightlyfromtheoriginalmanufacturersproductdatasheet. |
| InChiKey | UVFAEQZFLBGVRM-FEIGSSFXSA-N |
| ShippingandHandling | |
| Shipping | BLUEICE |
| ShortTermStorage | +4°C |
| LongTermStorage | -20°C |
| HandlingAdvice | Avoidfreeze/thawcycles. Protectfromlight. |
| Use/StABIlity | Stableforatleast1yearafterreceiptwhenstoredat-20°C. |
| Documents | |
| MSDS | No |
| ProductSpecificationSheet | |
| Datasheet |  DownloadPDF |
Suc-LLVY-AMCisafluorogenicsubstrateformeasuringthechymotrypsin-likepeptidaseactivityofthe20Sand26Sproteasome,calpainsandotherchymotrypsin-likeproteases.CleavageofthepeptidebytheenzymesliberatesthefluorophoreAMCwhichgeneratesstrongincreaseinfluorescencefluorescentthatcanbemonitoredfluorimetrically.
Excitation=345nm
Emission=445nm.
Excitation=345nm
Emission=445nm.
ProductReferences
- ComparativespecificityandkineticstudiesonporcinecalpainIandcalpainIIwithnaturallyoccurringpeptidesandsyntheticfluorogenicsubstrates:T.Sasaki,etal.;J.Biol.Chem.259,12489(1984)
- Kineticcharacterizationofthechymotrypticactivityofthe20Sproteasome:R.L.Stein,etal.;Biochemistry35,3899(1996)
- 26Sproteasomeactivityisdown-regulatedinlungcancerstem-likecellspropagatedinvitro:J.Pan,etal.;PLoSOne5,e13298(2010)
- Lowcelldensityinducedepithelial-mesenchymaltransitioninMCF10Acellisregulatedbyproteasomeactivity:J.Fu,etal.;J.Oncobiomark.1,4(2013)
- MarchantinM:anovelinhibitorofproteasomeinducesautophagiccelldeathinprostatecancercells:H.Jiang,etal.;CellDeathDis.4,e761(2013)
品牌介绍
Adipogen公司由三个子公司组成，分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国，运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发，如癌症、免疫、炎症、代谢疾病（糖尿病、肥胖）、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外，也可提供抗体和蛋白产品，Adipogen拥有自己的化学实验室，致力于开发创新型小分子化合物。
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