Adipogen/Stigmasterol/AG-CN2-0412-G005/5 g
商品编号：
AG-CN2-0412-G005
品牌：
Adipogen Inc
市场价：
¥3200.00
美元价：
1920.00
产品分类：
其他试剂
公司分类：
Other_reagents
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| ProductDetails | |
|---|---|
| Synonyms | Stigmasterin;Phytosterol;β-Stigmasterol;Serposterol;Wulzenanti-stiffnessFactor;NSC8095 |
| ProductType | Chemical |
| Properties | |
| Formula | C29H48O |
| MW | 412.7 |
| CAS | 83-48-7 |
| Source/HostChemicals | Synthetic.Originallyisolatedfromvariousplantsandmarineorganisms. |
| PurityChemicals | ≥95%(NMR) |
| Appearance | Whitetooff-whitesolid. |
| Solubility | SolubleinDMSO,ethanolordimethylformamide.Sparinglysolubleinwater. |
| Identity | Determinedby1-H-NMR. |
| InChiKey | HCXVJBMSMIARIN-PHZDYDNGSA-N |
| ShippingandHandling | |
| Shipping | AMBIENT |
| ShortTermStorage | +4°C |
| LongTermStorage | -20°C |
| HandlingAdvice | Keepcoolanddry. Protectfromlightandmoisture. |
| Use/StABIlity | Stableforatleast2yearsafterreceiptwhenstoredat-20°C. |
| Documents | |
| MSDS |  DownloadPDF |
| ProductSpecificationSheet | |
| Datasheet | DownloadPDF |
- Anti-hypercholestrolemiccompound[1,7].
- Anti-inflammatoryandimmune-modulatingeffects[2,4].
- Anticancercompound.Chemopreventive[3,12,13].
- Cytostatic.Cellgrowthinhibitor[5].
- Antimutagenic[6].
- PotentinvitroantagoNISTofFXR(farnesoidXreceptor)[8].
- DNApolymeraseβinhibitor[9].
- Potentantioxidant,hypoglycemicandthyroidinhibitingagent[10].
- Anti-osteoarthritic.Decreasestheexpressionofmatrixmetalloproteinases[11].
- Neuroprotective[15].
- IsusedasaprecursorforsyntheticprogesteroneandvitaminD3andisanintermediateinthebiosynthesisofandrogens,estrogensandcorticoids[14].
ProductReferences
- Antihypercholesterolemicstudieswithsterols:beta-sitosterolandstigmasterol:R.F.Chandler,etal.;J.Pharm.Sci.68,245(1979)
- TopicalantiinflammatoryactivityofphytosterolsisolatedfromEryngiumfoetidumonchronicandacuteinflammationmodels:M.D.Garcia,etal.;Phytother.Res.13,78(1999)
- Phytosterolsasanticancerdietarycomponents:evidenceandmechanismofaction:A.B.Awad&C.S.Fink;J.Nutr.130,2127(2000)(Review)
- Anti-InflammatoryandImmunomodulatingPropertiesofaSterolFractionfromSideritisfoetensCLEM:N.Antonio,etal.; Biol.Pharm.Bull.24,470(2001)
- CyostaticactivityofAchilleaageratumL.:M.A.Gomez,etal.;Phytother.Res.15, 633(2001)
- AntimutagenicConstituentsfromtheThornsofGleditsiasinensis:L.Jae-Chul,etal.;Chem.Pharm.Bull.53,561(2005)
- Stigmasterolreducesplasmacholesterollevelsandinhibitshepaticsynthesisandintestinalabsorptionintherat:A.K.Batta,etal.;Metabolism55,292(2006)
- Stigmasterol,asoylipid-derivedphytosterol,isanantagonistofthebileacidnuclearreceptorFXR:B.A.Carter,etal.;Pediatr.Res.62,301(2007)
- InhibitorsofDNApolymeraseβ:Activityandmechanism:G.Zhijie,etal.;Bioorg.Med.Chem.16, 4331(2008)
- Thyroidinhibitory,antiperoxidativeandhypoglycemiceffectsofstigmasterolisolatedfromButeamonosperma:S.Panda,etal.;Fitoterapia80,123(2009)
- Stigmasterol:aphytosterolwithpotentialanti-osteoarthriticproperties:O.Gabay,etal.;OsteoarthritisCartilage18,106(2010)
- CytotoxicandapoptoticeffectsoftheoxidizedderivativesofstigmasterolintheU937humanmonocyticcellline:Y.C.O"Callaghan,etal.;J.Agric.FoodChem.58,10793(2010)
- Phytosterols:perspectivesinhumannutritionandclinicaltherapy:S.P.Choudhary&L.S.Tran;Curr.Med.Chem.18,4557(2011)(Review)
- Stigmasterol:Acomprehensivereview:N.Kaur,etal.;IJPSR2,2259(2011)(Review)
- RhinacanthusnasutusExtractsPreventGlutamateandAmyloid-βNeurotoxicityinHT-22MouseHippocampalCells:PossIBLeActiveCompoundsIncludeLupeol,Stigmasterolandβ-Sitosterol:J.M.Brimson,etal.;Int.J.Mol.Sci.13,5074(2012)
品牌介绍
Adipogen公司由三个子公司组成，分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国，运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发，如癌症、免疫、炎症、代谢疾病（糖尿病、肥胖）、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外，也可提供抗体和蛋白产品，Adipogen拥有自己的化学实验室，致力于开发创新型小分子化合物。
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