Adipogen/Stevioside . hydrate/AG-CN2-0077-M010/10 mg
商品编号：
AG-CN2-0077-M010
品牌：
Adipogen Inc
市场价：
¥1200.00
美元价：
720.00
产品分类：
其他试剂
公司分类：
Other_reagents
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| ProductDetails | |
|---|---|
| Synonyms | BRN0077427;CCRIS6116 |
| ProductType | Chemical |
| Properties | |
| Formula | C38H60O18.xH2O |
| MW | 804.9(anhydrousbasis) |
| CAS | 57817-89-7(anhydrous) |
| Source/HostChemicals | IsolatedfromSteviarebaudiana. |
| PurityChemicals | ≥95%(HPLC) |
| Appearance | Whitesolid. |
| Solubility | Solubleinwater. |
| Identity | Determinedby1H-NMR. |
| OtherProductData | Watercontent:2-5% |
| InChiKey | UEDUENGHJMELGK-ZBVPAOMMSA-N |
| ShippingandHandling | |
| Shipping | AMBIENT |
| ShortTermStorage | +4°C |
| LongTermStorage | +4°C |
| HandlingAdvice | Hygroscopic. |
| Use/StABIlity | Stableforatleast2yearsafterreceiptwhenstoredat+4°C. |
| Documents | |
| MSDS |  DownloadPDF |
| ProductSpecificationSheet | |
| Datasheet | DownloadPDF |
- Noncaloricnaturalsweetener,300timesmorepotentthansucrose[1].
- Antidiabetic.Antihyperglycaemicandantihypoglycaemic.Potentiatesinsulinsecretion.Enhancesacetyl-CoAcarboxylase(ACC)geneexpression.Increasesinsulinsensitivity.[2,4,6-9,11].
- Antihypertensive.Ca2+influxinhibitor[3,6].
- Anticancercompound[5].
- Chemopreventive[14].
- Anti-inflammatory.IKKβ,NF-κBandMAPKsignalinginhibitor.InducesTNF-α,IL-1βandnitricoxiderelease[10,17,18].
- Immunomodulator.Increaseesphagocyticactivity,haemagglutinationantibodytitre,delayedtypehypersensitivity.IncreasedproliferationinLPSandConAstimulatedBandTcells[12].
- Peripheralμ-opioidreceptorsactivator.Importantforregulationofglucosehomeostasis[15].
- Anti-atherosclerotic[16].
- Review[13].
ProductReferences
- Lettertotheeditor:stevioside,anaturalsweeteningagent:C.Taylor;Am.J.Clin.Nutr.22,4(1969)
- Steviosideactsdirectlyonpancreaticbetacellstosecreteinsulin:actionsindependentofcyclicadenosinemonophosphateandadenosinetriphosphate-sensitiveK+-channelactivity:P.B.Jeppesen,etal.;Metabolism49,208(2000)
- Inhibitoryeffectofsteviosideoncalciuminfluxtoproduceantihypertension:C.N.Lee,etal.;PlantaMed.67,796(2001)
- Steviosideinducesantihyperglycaemic,insulinotropicandglucagonostaticeffectsinvivo:studiesinthediabeticGoto-Kakizaki(GK)rats:P.B.Jeppesen,etal.;Phytomedicine9,9(2002)
- Inhibitoryeffectofsteviosideontumorpromotionby12-O-tetradecanoylphorbol-13-acetateintwo-stagecarcinogenesisinmouseskin:K.Yasukawa,etal.;Biol.Pharm.Bull.25,1488(2002)
- Antihyperglycemicandbloodpressure-reducingeffectsofsteviosideinthediabeticGoto-Kakizakirat:P.B.Jeppesen,etal.;Metabolism52,372(2003)
- Antihyperglycemiceffectsofsteviosideintype2diabeticsubjects:S.Gregersen,etal.;Metabolism53,73(2004)
- Effectsofsteviosideonglucosetransportactivityininsulin-sensitiveandinsulin-resistantratskeletalmuscle:N.Lailerd,etal.;Metabolism53,101(2004)
- Mechanismofthehypoglycemiceffectofstevioside,aglycosideofSteviarebaudiana:T.H.Chen,etal.; PlantaMed.71,108(2005)
- Anti-InflammatoryandImmunomodulatoryActivitiesofSteviosideandItsMetaboliteSteviolonTHP-1Cells:C.Boonkaewwan,etal.;J.Agric.FoodChem.54,785(2006)
- Steviosideimprovespancreaticbeta-cellfunctionduringglucotoxicityviaregulationofacetyl-CoAcarboxylase:J.Chen,etal.;Am.J.Physiol.Endocrinol.Metab.292,E1906(2007)
- Immuneupregulatoryresponseofanon-caloricnaturalsweetener,stevioside:I.Sehar,etal.;Chem.Biol.Interact.173,115(2008)
- Steviosideandrelatedcompounds:therapeuticbenefitsbeyondsweetness:V.Chatsudthipong&C.Muanprasat;Pharmacol.Ther.121,41(2009)(Review)
- Cancerpreventiveagents.Part8:Chemopreventiveeffectsofsteviosideandrelatedcompounds:M.Takasaki,etal.;Bioorg.Med.Chem.17,600(2009)
- Stimulatoryeffectofsteviosideonperipheralmuopioidreceptorsinanimals:P.S.Yang,etal.;Neurosci.Lett.454,72(2009)
- Steviosideinhibitsatherosclerosisbyimprovinginsulinsignalingandantioxidantdefenseinobeseinsulin-resistantmice:B.Geeraert,etal.;Int.J.Obes.34,569(2010)
- Steviosideameliorateshigh-fatdiet-inducedinsulinresistanceandADIposetissueinflammationbydownregulatingtheNF-κBpathway:Z.Wang,etal.;BBRC417,1280(2012)
- SteviosideSuppressedInflammatoryCytokineSecretionbyDownregulationofNF-κBandMAPKSignalingPathwaysinLPS-StimulatedRAW264.7Cells:L.Fengyang,etal.;Inflammation35,1669(2012)
品牌介绍
Adipogen公司由三个子公司组成，分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国，运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发，如癌症、免疫、炎症、代谢疾病（糖尿病、肥胖）、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外，也可提供抗体和蛋白产品，Adipogen拥有自己的化学实验室，致力于开发创新型小分子化合物。
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