Adipogen/Sterigmatocystin/BVT-0171-M005/5 mg
商品编号：
BVT-0171-M005
品牌：
Adipogen Inc
市场价：
¥2400.00
美元价：
1440.00
产品分类：
其他试剂
公司分类：
Other_reagents
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| Product Details | |
|---|---|
| Synonyms | NSC 201423; NSC 204985 |
| Product Type | Chemical |
| Properties | |
| Formula | C18H12O6 |
| MW | 324.3 |
| CAS | 10048-13-2 |
| RTECS | LV1750000 |
| Source/Host Chemicals | Isolated from Aspergillus sp. (strain WDMH51). |
| Purity Chemicals | ≥98% (HPLC; NMR) |
| Appearance | Pale yellow powder. |
| Solubility | Soluble in DMSO, ethanol, methanol, pyridine or acetone. |
| Identity | Determined by 1H-NMR. |
| Declaration | Manufactured by BioViotica. |
| InChi Key | UTSVPXMQSFGQTM-DCXZOGHSSA-N |
| Shipping and Handling | |
| Shipping | AMBIENT |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Handling Advice | Protect from light. |
| Use/Stability |
Stable for at least 1 year after receipt when stored at -20°C. After reconstitution protect from light at -20°C. |
| Documents | |
| MSDS |
 Download PDF |
| Product Specification Sheet | |
| Datasheet |
Download PDF |
- Intermediate of the biosynthetic pathway to aflatoxin B1.
- Mycotoxin.
- DNA synthesis inhibitor.
- Anticancer compound. Cytotoxic, carcinogenic and mutagenic.
- Acyl-CoA:cholesterol acyltransferase 2 (ACAT2) inhibitor.
- Shown to induce apoptosis in human peripheral lymphocytes and necrosis in rat liver.
- Induces sister chromatid exchanges in murine bone marrow cells.
Product References
- Sterigmatocystin, a metabolite of Aspergillus versicolor: J. E. Davies, et al.; J. Chem. Soc. 1960, 2169 (1960)
- Massive and single cell necrosis in the rat liver induced by aflatoxin B1 and sterigmatocystin: K. Terao; Acta Pathol. Jpn. 23, 647 (1973)
- Fermentation, isolation, and antitumor activity of sterigmatocystins: W.T. Bradner, et al.; Antimicrob. Agents Chemother. 8, 159 (1975)
- Biosynthesis of aflatoxins. Incorporation of acetate into sterigmatocystin in Aspergillus versicolor: T. J. Simpson and D. J. Stenzel; JCS Chem. Commun. 1982, 890 (1982)
- Induction of sister-chromatid exchanges in vivo in mice by the mycotoxins sterigmatocystin and griseofulvin: P.T. Curry, et al.; Mutat. Res. 137, 111 (1984)
- Inhibitory effect of sterigmatocystin and 5,6-dimethoxysterigmatocystin on ATP synthesis in mitochondria: K. Kawai, et al.; Appl. Environ. Microbiol. 48, 1001 (1984)
- Effects of sterigmatocystin, deoxynivalenol and aflatoxin G1 on apoptosis of human peripheral blood lymphocytes in vitro: X.M. Sun, et al.; Biomed. Environ. Sci. 15, 145 (2002)
- Cytotoxicity of occupationally and environmentally relevant mycotoxins: J. Bunger, et al.; Toxicology 202, 199 (2004)
- Selective inhibition of Acyl-CoA: cholesterol acyltransferase 2 isozyme by flavasperone and Sterigmatocystin from Aspergillus species: K. Sakai, et al.; J. Antibiot. 61, 568 (2008)
- Bioactive metabolites from the sponge-derived fungus Aspergillus versicolor: Y. M. Lee, et al.; Arch. Pharm. Res. 33, 231 (2010)
- Long-term administration of the fungus toxin, Sterigmatocystin, induces intestinal metaplasia and increases the proliferative activity of PCNA, p53, and MDM2 in the gastric mucosa of aged Mongolian gerbils: M. Kusunoki, et al.; Environ Health Prev. Med. 16, 224 (2011)
- Effects of Sterigmatocystin on TNF-alpha, IL-6 and IL-12 expression in murine peripheral blood mononuclear cells and peritoneal macrophages in vivo: Y. Zhang, et al.; Mol. Med. Rep. 5, 1318 (2012)
- Emerging Mycotoxins: Beyond Traditionally Determined Food Contaminants: C. Gruber-Dorninger, et al.; J. Agr. Food Chem. (Epub ahead of print) (2016)
- Cytotoxic effects induced by patulin, sterigmatocystin and beauvericin on CHO-K1 cells: N. Zouaoui, et al.; Food Chem. Toxicol. 89, 92 (2016)
- A highly specific competitive direct enzyme immunoassay for sterigmatocystin as a tool for rapid immunochemotaxonomic differentiation of mycotoxigenic Aspergillus species: S. Wegner, et al.; Lett. Appl. Microbiol. 64, 124 (2017)
品牌介绍
Adipogen公司由三个子公司组成，分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国，运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发，如癌症、免疫、炎症、代谢疾病（糖尿病、肥胖）、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外，也可提供抗体和蛋白产品，Adipogen拥有自己的化学实验室，致力于开发创新型小分子化合物。
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