Adipogen/SNC80/AG-CR1-0017-M005/5 mg
商品编号：
AG-CR1-0017-M005
品牌：
Adipogen Inc
市场价：
¥1200.00
美元价：
720.00
产品分类：
其他试剂
公司分类：
Other_reagents
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| ProductDetails | |
|---|---|
| Synonyms | (+)-4-[(αR)-α-((2S,5R)-4-Allyl-2,5-dimethyl-1-piperazinyl)-3-methoxybenzyl]-N,N-diethylbenzamide |
| ProductType | Chemical |
| Properties | |
| Formula | C28H39N3O2 |
| MW | 449.6 |
| CAS | 156727-74-1 |
| PurityChemicals | ≥99%(NMR) |
| Appearance | Whitetooff-whitecrystallinesolid. |
| Solubility | Solublein100%ethanol,DMSOordichloromethane. |
| InChiKey | KQWVAUSXZDRQPZ-UMTXDNHDSA-N |
| ShippingandHandling | |
| Shipping | AMBIENT |
| ShortTermStorage | +4°C |
| LongTermStorage | +4°C |
| Use/StABIlity | Stableforatleast2yearsafterreceiptwhenstoredat+4°C. |
| Documents | |
| MSDS |  DownloadPDF |
| ProductSpecificationSheet | |
| Datasheet | DownloadPDF |
- Highlyselectiveandpotentnon-peptideδ-opioidreceptoragoNIST[1-3].
- Mediatesdownregulationoftheδ-opioidreceptor[4].
- Showsantidepressant-likeeffects[5,8].
- Modulatesvoltage-dependentsodiumchannels[6].
- Antinociceptive[7].
- ActivatesATP-sensitiveK+channels[7].
- Enhancesamphetamine-mediateddopamineefflux[9].
ProductReferences
- Probesfornarcoticreceptormediatedphenomena.19.Synthesisof(+)-4-[(alphaR)-alpha-((2S,5R)-4-allyl-2,5-dimethyl-1-piperazinyl)-3-methoxybenzyl]-N,N-diethylbenzamide(SNC80):ahighlyselective,nonpeptidedeltaopioidreceptoragonist:S.N.Calderon,etal.;J.Med.Chem.37,2125(1994)
- SNC80,aselective,nonpeptidicandsystemicallyactiveopioiddeltaagonist:E.J.Bilsky,etal.;J.Pharmacol.Exp.Ther.273,359(1995)
- Structure-activityrelationshipsforSNC80andrelatedcompoundsatclonedhumandeltaandmuopioidreceptors:R.J.Knapp|etal.;J.Pharmacol.Exp.Ther.277,1284(1996)
- Differentialdown-regulationofthehumandelta-opioidreceptorbySNC80and[D-Pen(2),D-Pen(5)]enkephalin:T.Okura,etal.;Eur.J.Pharmacol.387,R11(2000)
- Potentialanxiolyticandantidepressant-likeactivitiesofSNC80,aselectivedelta-opioidagonist,inbehavioralmodelsinrodents:A.Saitoh,etal.;J.Pharmacol.Sci.95,374(2004)
- Modulationofvoltage-dependentsodiumchannelsbythedelta-agonistSNC80inacutelyisolatedrathippocampalneurons:C.Remy,etal.;Neuropharmacology47,1102(2004)
- Delta-opioidreceptoragonistSNC80inducesperipheralantinociceptionviaactivationofATP-sensitiveK+channels:D.F.Pacheco&I.D.Duarte;Eur.J.Pharmacol.512,23(2005)
- Antidepressant-likeeffectsofthedelta-opioidreceptoragonistSNC80([(+)-4-[(alphaR)-alpha-[(2S,5R)-2,5-dimethyl-4-(2-propenyl)-1-piperazinyl]-(3-methoxyphenyl)methyl]-N,N-diethylbenzamide)inanolfactorybulbectomizedratmodel:A.Saitoh,etal.;BrainRes.1208,160(2008)
- TheselectivedeltaopioidagonistSNC80enhancesamphetamine-mediatedeffluxofdopaminefromratstriatum:K.E.Bosse,etal.;Neuropharmacology55,755(2008)
品牌介绍
Adipogen公司由三个子公司组成，分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国，运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发，如癌症、免疫、炎症、代谢疾病（糖尿病、肥胖）、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外，也可提供抗体和蛋白产品，Adipogen拥有自己的化学实验室，致力于开发创新型小分子化合物。
联络我们
