Adipogen/Sirtinol/AG-CR1-0055-M005/5 mg
商品编号：
AG-CR1-0055-M005
品牌：
Adipogen Inc
市场价：
¥1300.00
美元价：
780.00
产品分类：
其他试剂
公司分类：
Other_reagents
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| ProductDetails | |
|---|---|
| Synonyms | SirTwoInhibitorNaphthol;2-[(2-Hydroxynaphthalen-1-yl-methylene)amino]-N-(1-phenethyl)benzamide |
| ProductType | Chemical |
| Properties | |
| Formula | C26H22N2O2 |
| MW | 394.5 |
| CAS | 410536-97-9 |
| PurityChemicals | ≥98%(NMR) |
| Appearance | Off-whitetoyellowsolid. |
| Solubility | SolubleinDMSO,100%ethanolordimethylformamide. |
| OtherProductData | Relativelyunstableinaqueoussolution,especiallyatacidicpH. |
| InChiKey | UXJFDYIHRJGPFS-WPWMEQJKSA-N |
| ShippingandHandling | |
| Shipping | AMBIENT |
| ShortTermStorage | +4°C |
| LongTermStorage | +4°C |
| HandlingAdvice | Protectfromlight. |
| Use/StABIlity | Stableforatleast2yearsafterreceiptwhenstoredat+4°C. |
| Documents | |
| MSDS |  DownloadPDF |
| ProductSpecificationSheet | |
| Datasheet | DownloadPDF |
- SpecificcellpermeableSIRT1(sirtuin1)inhibitor[1,2].
- Senescence-likegrowtharrestinducer[3].
- Plateletaggregationinhibitor[4].
- Apoptosisinducer[5].
ProductReferences
- IdentificationofaclassofsmallmoleculeinhibitorsofthesirtuinfamilyofNAD-dependentdeacetylasesbyphenotypicscreening:C.M.Grozinger,etal.;J.Biol.Chem.276,38837(2001)
- Design,synthesis,andBIOLOGicalevaluationofsirtinolanaloguesasclassIIIhistone/proteindeacetylase(Sirtuin)inhibitors:A.Mai,etal.;J.Med.Chem.48,7789(2005)
- Sirt1inhibitor,Sirtinol,inducessenescence-likegrowtharrestwithattenuatedRas-MAPKsignalinginhumancancercells:H.Ota,etal.;Oncogene25,176(2006)
- Anewinsightofanti-plateleteffectsofsirtinolinplateletsaggregationviacyclicAMPphosphodiesterase:F.C.Liu,etal.;Biochem.Pharmacol.77,1364(2009)
- SIRTinhibitorsinducecelldeathandp53acetylationthroughtargetingbothSIRT1andSIRT2:B.Peck,etal.;Mol.CancerTher.9,844(2010)
品牌介绍
Adipogen公司由三个子公司组成，分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国，运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发，如癌症、免疫、炎症、代谢疾病（糖尿病、肥胖）、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外，也可提供抗体和蛋白产品，Adipogen拥有自己的化学实验室，致力于开发创新型小分子化合物。
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