Adipogen/Sipholenone A/AG-CN2-0507-C100/100 µg
商品编号：
AG-CN2-0507-C100
品牌：
Adipogen Inc
市场价：
¥2700.00
美元价：
1620.00
产品分类：
其他试剂
公司分类：
Other_reagents
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| ProductDetails | |
|---|---|
| Synonyms | NSC378978 |
| ProductType | Chemical |
| Properties | |
| Formula | C30H50O4 |
| MW | 474.7 |
| CAS | 78518-74-8 |
| Source/HostChemicals | IsolatedfrommarinespongeSiphonochalinasIphonella. |
| PurityChemicals | ≥98%(HPLC) |
| Appearance | Whitetooff-whitelyophilizedpowder. |
| Solubility | SolubleinDMSOor100%ethanol(25mg/ml). |
| InChiKey | LKZQMXLIWZQEEU-KOGSSWOMSA-N |
| ShippingandHandling | |
| Shipping | AMBIENT |
| ShortTermStorage | +4°C |
| LongTermStorage | -20°C |
| HandlingAdvice | Keepcoolanddry. |
| Use/StABIlity | Stableforatleast2yearsafterreceiptwhenstoredat-20°C. |
| Documents | |
| MSDS |  DownloadPDF |
| ProductSpecificationSheet | |
| Datasheet | DownloadPDF |
- EfficientinhibitorofP-glycoprotein(Pgp,MDR-1)functionthroughdirectinteractions.ByinhibitingMDR-1,activecompoundsremaininthecytoplasmlongerandallowingthemtobemoreeffectivewithinthecell.
- Reversingagentforthetreatmentofmultidrugresistance(MDR)inPgp-overexpressingtumors.PotentiatesthecytotoxicityofestablishedPgpsubstratessuchascolchicine,vinblastineandpaclitaxel.
- Antiproliferative,antiangiogenicandcytotoxiccompound.
- Moderateantifoulingcompound.
ProductReferences
- Thesipholanes,anovelgroupoftriterpenesfromthemarinespongeSiphonochalinasiphonella:S.Carmely&Y.Kashman;J.Org.Chem.48,3517(1983)
- NewtriterpenoidsfromtheRedSeaspongeSiphonochalinasiphonella:Y.Kashman,etal.;J.Nat.Prod.64,175(2001)
- Biocatalysisoftheanticancersipholanetriterpenoids:S.Jain,etal.;PlantaMed.73,591(2007)
- SipholenolA,amarine-derivedsipholanetriterpene,potentlyreversesP-glycoprotein(ABCB1)-mediatedmultidrugresistanceincancercells:Z.Shi,etal.;CancerSci.98,1373(2007)
- Sipholanetriterpenoids:chemistry,reversalofABCB1/P-glycoprotein-mediatedmultidrugresistance,andpharmacophoremodeling:S.Jain,etal.;J.Nat.Prod.72,1291(2009)
- Estersofthemarine-derivedtriterpenesipholenolAreverseP-GP-mediateddrugresistance:Y.Zhang,etal.;Mar.Drugs13,2267(2015)
- PotentantifoulingmetabolitesfromRedSeaorganisms:S.S.Al-Lihaibi,etal.;AsianJ.Chem.27,2252(2015)
- Antiproliferativeeffectsoftriterpenoidalderivatives,obtainedfromthemarinespongeSiphonochalinasp.onhumanhepaticandcolorectalcancercells:A.ABDel-Lateff,etal.;Z.Naturforsch.C.71,29(2016)
品牌介绍
Adipogen公司由三个子公司组成，分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国，运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发，如癌症、免疫、炎症、代谢疾病（糖尿病、肥胖）、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外，也可提供抗体和蛋白产品，Adipogen拥有自己的化学实验室，致力于开发创新型小分子化合物。
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