脂肪原/西环克隆D8/BVT-0290-M001/1 mg
商品编号：
BVT-0290-M001
品牌：
Adipogen Inc
市场价：
¥1800.00
美元价：
1080.00
产品分类：
其他试剂
公司分类：
Other_reagents
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| ProductDetails | |
|---|---|
| ProductType | Chemical |
| Properties | |
| Formula | C46H42ClNO18 |
| MW | 932.3 |
| CAS | 301845-97-6 |
| Source/HostChemicals | IsolatedfromStreptomycesantibioticusTü6040. |
| PurityChemicals | ≥97%(HPLC) |
| Appearance | Yellowpowder. |
| Solubility | SolubleinDMSO,methanol,acetone,dichloromethaneorethylacetate. |
| Identity | Determinedby1H-NMR. |
| Declaration | ManufacturedbyBioViotica. |
| InChiKey | PLEGMCYXNQPJNV-TYXWGSLYSA-N |
| ShippingandHandling | |
| Shipping | AMBIENT |
| ShortTermStorage | +4°C |
| LongTermStorage | -20°C |
| HandlingAdvice | Protectfromlightwheninsolution. |
| Use/StABIlity | Stableforatleast1yearafterreceiptwhenstoredat-20°C. Afterreconstitutionprotectfromlightat-20°C. |
| Documents | |
| MSDS |  DownloadPDF |
| ProductSpecificationSheet | |
| Datasheet | DownloadPDF |
- Antibiotic.
- BacterialDNAgyraseinhibitor:Staphylococcusaureus(IC50=1.45µM),E.coli(IC50=0.41µM).
- HumantopoisomeraseII(TopoII)inhibitor(IC50=100µM).
- Antibacterial(Gram-positive).
- Antitumorcompound.
ProductReferences
- Simocyclinones,novelcytostaticangucyclinoneantibioticsproducedbyStreptomycesantibioticusTu6040.I.Taxonomy,fermentation,isolationandBIOLOGicalactivities:J.Schimana,etal.;J.Antibiot.53,779(2000)
- BiosynthesisofsimocyclinoneD8inan18O2-richatmosphere:M.Holzenkämpfer&A.Zeeck;J.Antibiot.55,341(2002)
- Simocyclinones,novelcytostaticangucyclinoneantibioticsproducedbyStreptomycesantibioticusTu6040II.Structureelucidationandbiosynthesis:M.Holzenkämpfer,etal.;J.Antibiot.55,301(2002)
- SimocyclinoneD8,aninhibitorofDNAgyrasewithanovelmodeofaction:R.H.Flatman,etal.;Antimicrob.AgentsChemother.49,1093(2005)
- AcrystalstructureofthebifunctionalantibioticsimocyclinoneD8,boundtoDNAgyrase:M.J.Edwards,etal.;Science326,1415(2009)
- InvivoandinvitropatternsoftheactivityofsimocyclinoneD8,anangucyclinoneantibioticfromStreptomycesantibioticus:L.M.Oppegard,etal.;Antimicrob.AgentsChemother.53,2110(2009)
- MappingsimocyclinoneD8interactionwithDNAgyrase:evidenceforanewbindingsiteonGyrB:C.Sissi,etal.;Antimicrob.AgentsChemother.54,213(2009)
- Theaminocoumarins:biosynthesisandbiology:L.Heide;Nat.Prod.Rep.26,1241(2009)(Review)
- Anti-proliferativeeffectsofsimocyclinoneD8(SD8),anovelcatalyticinhibitoroftopoisomeraseII:A.A.SADIq,etal.;InvestNewDrugs28,20(2010)
品牌介绍
Adipogen公司由三个子公司组成，分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国，运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发，如癌症、免疫、炎症、代谢疾病（糖尿病、肥胖）、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外，也可提供抗体和蛋白产品，Adipogen拥有自己的化学实验室，致力于开发创新型小分子化合物。
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