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当前位置: 首页 > 产品中心 > Other_reagents > Adipogen/Sclerotiorin/AG-CN2-0054-M005/5 mg
商品详细Adipogen/Sclerotiorin/AG-CN2-0054-M005/5 mg
Adipogen/Sclerotiorin/AG-CN2-0054-M005/5 mg
Adipogen/Sclerotiorin/AG-CN2-0054-M005/5 mg
商品编号: AG-CN2-0054-M005
品牌: Adipogen Inc
市场价: ¥15000.00
美元价: 9000.00
产地: 美国(厂家直采)
公司:
产品分类: 其他试剂
公司分类: Other_reagents
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
MoreInformation
ProductDetails
Synonyms(S-(R*,R*-(E,E)))-Sclerotiorin
ProductTypeChemical
Properties
FormulaC21H23ClO5
MW390.9
CAS549-23-5
Source/HostChemicalsIsolatedfromfungusPenicilliumsp.
PurityChemicals≥97%(HPLC)
AppearanceYellowsolid.
SolubilitySolubleinDMSO,ethanolorDMF.Sparinglysolubleinaqueousbuffers.
IdentityDeterminedby1H-NMR.
OtherProductDataSolubilityinaqueousbuffers:DissolveinDMFandthendilutewiththeaqueousbufferofchoice.Sclerotiorinhasasolubilityofapprox.0.3mg/mlina1:2solutionofDMF:PBS(pH7.2)usingthismethod.Wedonotrecommendstoringtheaqueoussolutionformorethanoneday.
InChiKeySWJLTKXURNHVHE-UPWXJBBJSA-N
ShippingandHandling
ShippingAMBIENT
ShortTermStorage+4°C
LongTermStorage-20°C
Use/StABIlityStableforatleast2yearsafterreceiptwhenstoredat-20°C.
Documents
MSDSDownloadPDF
ProductSpecificationSheet
DatasheetDownloadPDF
  • Antibiotic[4,6,7].
  • Antibacterial[4,6,7]withanticanceractivity[8].
  • WeakantagoNISTofhumanendothelinreceptorA(ETA)andB(ETB)[1].
  • Cholesterylestertransferprotein(CETP)activityinhibitor[2].
  • Grb2-Shcbindinginhibitor[3].
  • Potentaldosereductaseinhibitor[4].
  • PotentreversIBLe,non-competitivesoybeanlipoxygenase-1(LOX-1)inhibitor[5].
  • Antioxidant.FreerADIcalscavenger[5].
  • Antifungal[6,7].
ProductReferences
  1. AzaphiloneswithendothelinreceptorbindingactivityproducedbyPenicilliumsclerotiorum:taxonomy,fermentation,isolation,structureelucidationandBIOLOGicalactivity:L.Pairet,etal.;J.Antibiot.(Tokyo)48,913(1995)
  2. Structure-specificinhibitionofcholesterylestertransferproteinbyazaphilones:H.Tomoda,etal.;J.Antibiot.(Tokyo)52,160(1999)
  3. SclerotiorinandisochromophiloneIV:InhibitorsofGrb2-Shcinteraction,isolatedfromPenicilliummulticolorF1753:N.Ji-Youn,etal.;J.Microbiol.Biotechnol.10,544(2000)
  4. Sclerotiorin,fromPenicilliumfrequentans,apotentinhibitorofaldosereductase:C.Chidananda,etal.;Biotechnol.Lett.28,1633(2006)
  5. Sclerotiorin,anovelinhibitoroflipoxygenasefromPenicilliumfrequentans:C.Chidananda&A.P.Sattur;J.Agric.Food.Chem.55,2879(2007)
  6. Antimicrobialpropertiesofsclerotiorin,isocHromophiloneVIandpencolide,metabolitesfromaBraziliancerradoisolateofPenicilliumsclerotiorumvanBeyma:E.M.F.Lucas,etal.;Braz.J.Microbiol.38,785(2007)
  7. Synthesisandantifungalactivityofnovelsclerotiorinanalogues:L.Lin,etal.;J.Agric.FoodChem.60,4480(2012)
  8. Anticanceractivityofsclerotiorin,isolatedfromanendophyticfungusCephalothecafaveolata:P.Giridharan,etal.;IndianJ.Exp.Biol.50,464(2012)
品牌介绍
Adipogen公司由三个子公司组成,分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国,运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发,如癌症、免疫、炎症、代谢疾病(糖尿病、肥胖)、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外,也可提供抗体和蛋白产品,Adipogen拥有自己的化学实验室,致力于开发创新型小分子化合物。