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商品详细脂肪原/索奇农/AG-CN2-0032-M005/5毫克
脂肪原/索奇农/AG-CN2-0032-M005/5毫克
脂肪原/索奇农/AG-CN2-0032-M005/5毫克
商品编号: AG-CN2-0032-M005
品牌: Adipogen Inc
市场价: ¥1800.00
美元价: 1080.00
产地: 美国(厂家直采)
公司:
产品分类: 其他试剂
公司分类: Other_reagents
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
MoreInformation
ProductDetails
Synonyms1′-Epimerdihydrocarpanone
ProductTypeChemical
Properties
FormulaC20H20O6
MW356.4
CAS177931-17-8
Source/HostChemicalsIsolatedfromSaururuschinensis.
PurityChemicals≥98%(HPLC)
AppearanceWhitetooff-whitepowder.
SolubilitySolubleinDMSOorchloroform.
InChiKeyGMTJIWUFFXGFHH-WPAOEJHSSA-N
ShippingandHandling
ShippingAMBIENT
ShortTermStorage+4°C
LongTermStorage-20°C
HandlingAdviceKeepcoolanddry.
Use/StABIlityStableforatleast2yearsafterreceiptwhenstoredat-20°C.
Documents
MSDSDownloadPDF
ProductSpecificationSheet
DatasheetDownloadPDF
  • Hepatoprotectiveantioxidant[1,2,9].
  • Anti-inflammatory.SuppressesNF-kBp65activity[3,5].
  • Neuroprotective.Apoptosisinhibitor[4].
  • Boneresorption/osteoclastogenesisinhibitor.ReducesROSformation[6].
  • Antiseptic[7].
  • AMP-activatedkinase(AMPK)activator[8].
  • Aktphosphorylationinhibitor[10].
  • ArginaseIIinhibitor[11].
ProductReferences
  1. Sauchinone,alignanfromSaururuschinensis,attenuatesCCl4-inducedtoxicityinprimaryculturesofrathepatocytes:S.H.Sung,etal.;Biol.Pharm.Bull.23,666(2000)
  2. HepatoprotectivediastereomericlignansfromSaururuschinensisherbs:S.H.Sung&Y.C.Kim;J.Nat.Prod.63,1019(2000)
  3. Inhibitionoflipopolysaccharide-inducIBLenitricoxidesynthase,TNF-alphaandCOX-2expressionbysauchinoneeffectsonI-kappaBalphaphosphorylation,C/EBPandAP-1activation:A.K.Lee,etal.;Br.J.Pharmacol.139,11(2003)
  4. Sauchinone,alignanfromSaururuschinensis,inhibitsstaurosporine-inducedapoptosisinC6ratgliomacells:H.Song,etal.;Biol.Pharm.Bull.26,1428(2003)
  5. Sauchinone,alignanfromSaururuschinensis,suppressesiNOSexpressionthroughtheinhibitionoftransactivationactivityofRelAofNF-kappaB:B.Y.Hwang,etal.;PlantaMed.69,1096(2003)
  6. Inhibitionofosteoclastdifferentiationandboneresorptionbysauchinone:K.Y.Han,etal.;Biochem.Pharmacol.74,911(2007)
  7. ProtectiveeffectoflignansagainstsepsisfromtherootsofSaururuschinensis:C.S.Seo,etal.;Biol.Pharm.Bull.31,523(2008)
  8. EfficacyofsauchinoneasanovelAMPK-activatinglignanforpreventingiron-inducedoxidativestressandliverinjury:Y.W.Kim,etal.;FreeRADIc.Biol.Med.47,1082(2009)
  9. Nrf2-mediatedliverprotectionbysauchinone,anantioxidantlignan,fromacetaminophentoxicitythroughthePKCδ-GSK3βpathway:H.Y.Kay,etal.;Br.J.Pharmacol.163,1653(2011)
  10. Sauchinonesuppresseslipopolysaccharide-inducedinflammatoryresponsesthroughAktsignalinginBV2cells:E.Y.Yang,etal.;Int.Immunopharmacol.14,188(2012)
  11. ArginaseIIinhibitoryactivityofphenoliccompoundsfromSaururuschinensis:C.J.Lim,etal.;Bull.KoreanChem.Soc.33,3079(2012)
  12. PharmacokineticsandpharmacodynamicsofpromisingArginaseInhibitors:K.S.ABDelkawy,etal.;Eur.J.DrugMetab.Pharmacokinet.42,355(2017)Review
品牌介绍
Adipogen公司由三个子公司组成,分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国,运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发,如癌症、免疫、炎症、代谢疾病(糖尿病、肥胖)、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外,也可提供抗体和蛋白产品,Adipogen拥有自己的化学实验室,致力于开发创新型小分子化合物。