Adipogen/Rutin . trihydrate/AG-CN2-0408-G005/5 g
商品编号：
AG-CN2-0408-G005
品牌：
Adipogen Inc
市场价：
¥500.00
美元价：
300.00
产品分类：
其他试剂
公司分类：
Other_reagents
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| ProductDetails | |
|---|---|
| Synonyms | Quercetin-3-rutinoside;VitaminP;Rutoside;Phytomelin;Sophorin;Birutan;Eldrin;Globularicitrin;Oxyritin;Violaquercitrin;BRN0075455;C.I.75730;NSC9220 |
| ProductType | Chemical |
| Properties | |
| Formula | C27H30O16.3H20 |
| MW | 610.5.54.0 |
| CAS | 250249-75-3 |
| Source/HostChemicals | IsolatedfromRutagraveolens. |
| PurityChemicals | ≥95%(NMR) |
| Appearance | Paleyellowpowder. |
| Solubility | SolubleinDMSO,acetone,dichloromethaneorethylacetate. |
| Identity | Determinedby1H-NMR. |
| InChiKey | IKGXIBQEEMLURG-BNBQMXROSA-N |
| ShippingandHandling | |
| Shipping | AMBIENT |
| ShortTermStorage | +4°C |
| LongTermStorage | +4°C |
| HandlingAdvice | Protectfromlight. |
| Use/StABIlity | Stableforatleast2yearsafterreceiptwhenstoredat+4°C. |
| Documents | |
| MSDS |  DownloadPDF |
| ProductSpecificationSheet | |
| Datasheet | DownloadPDF |
- Antioxidant.FreerADIcalscavenger.Nitricoxide(NO)scavenger[1,5,6].
- Anticancercompound[2,18].
- Antiproliferative[10].
- Apoptosisinducer[11].
- ReducesinducedDNAdamage.Protectiveagainstcarcinogenesis[3].
- Hypolipidaemic.Reducestriacylglycerollevels[4].
- Anti-inflammatory[5,15].
- Plateletaggregationinhibitor[7].
- Anti-hyperglycaemic.Anti-Adipogenic[8,9].
- Insulin-mimetic.ActivatessynthesisofglucosetransporterGLUT4[17].
- Neuroprotective[16].
- Cardioprotective.Reduceslipidperoxidation[12].
- Weakα-glucosidaseinhibitor[13].
- Vasodilatorycompound[14].
- Brownfatactivator[19].
ProductReferences
- Chelatingandfreeradicalscavengingmechanismsofinhibitoryactionofrutinandquercetininlipidperoxidation:I.B.Afanas"ev,etal.;Biochem.Pharmacol.38,1763(1989)
- Quercetinandrutinasinhibitorsofazoxymethanol-inducedcolonicneoplasia:E.E.Deschner,etal.;Carcinogenesis12,1193(1991)
- Protectiveeffectofrutin,aflavonolglycoside,onthecarcinogen-inducedDNAdamageandrepairenzymesinrats:R.P.Webster,etal.;CancerLett.109,185(1996)
- Hypolipidaemiceffectsofnaringenin,rutin,nicotinicacidandtheirassociations:K.F.Santos,etal.;Pharmacol.Res.40,493(1999)
- Oxidativestressinrheumatoidarthritisleukocytes:suppressionbyrutinandotherantioxidantsandchelators:E.A.Ostrakhovitch&I.B.Afanas"ev;Biochem.Pharmacol.62,743(2001)
- Invitroandinvivoinhibitoryactivitiesofrutin,wogonin,andquercetinonlipopolysaccharide-inducednitricoxideandprostaglandinE(2)production:S.C.Shen,etal.;Eur.J.Pharmacol.446,187(2002)
- Mechanismsinvolvedintheantiplateletactivityofrutin,aglycosideoftheflavonolquercetin,inhumanplatelets:J.R.Shenetal.;J.Agric.FoodChem.52,4414(2004)
- Antihyperglycaemicandantioxidanteffectofrutin,apolyphenolicflavonoid,instreptozotocin-induceddiabeticwistarrats:N.Kamalakkannan&P.S.Prince;BasicClin.Pharmacol.Toxicol.98,97(2006)
- Anti-adipogenicactivityofrutinin3T3-L1cellsandmicefedwithhigh-fatdiet:I.Choi,etal.;Biofactors26,273(2006)
- RutininhibitstheproliferationofmurineleukemiaWEHI-3cellsinvivoandpromotesimmuneresponseinvivo:J.P.Lin|etal.;Leuk.Res.33,823(2009)
- TheflavonoidrutinbutnotthealkaloidarborinineinducesapoptosisinaB-cellhybridomacellline:R.Roseghini,etal.;PlantaMed.75,488(2009)
- Cardioprotectiveeffectoftetrahydrocurcuminandrutinonlipidperoxidesandantioxidantsinexperimentallyinducedmyocardialinfarctioninrats:M.S.Ali,etal.;Pharmazie64,132(2009)
- Comparativeevaluationofquercetin,isoquercetinandrutinasinhibitorsofalpha-glucosidase:Y.Q.Li,etal.;J.Agric.FoodChem.57,11463(2009)
- VasorelaxantandhypotensiveeffectsoftheextractandtheisolatedflavonoidrutinobtainedfromPolygalapaniculataL:R.LapaFda,etal.;J.Pharm.Pharmacol.63,875(2011)
- RutinattenuatescisplatininducedrenalinflammationandapoptosisbyreducingNFκB,TNF-αandcaspase-3expressioninwistarrats:W.Arjumand,etal.;FoodChem.Toxicol.49,2013(2011)
- Rutininhibitsβ-amyloidaggregationandcytotoxicity,attenuatesoxidativestress,anddecreasestheproductionofnitricoxideandproinflammatorycytokines:S.W.Wang,etal.;Neurotoxicology33,482(2012)
- InvolvementofGLUT-4inthestimulatoryeffectofrutinonglucoseuptakeinratsoleusmuscle:V.D.Kappel,etal.;J.Pharm.Pharmacol.65,1179(2013)
- RutinExertsAntitumorEffectsonNudeMiceBearingSW480Tumor:A.J.Alonso-Castro,etal.;Arch.Med.Res.44,346(2013)
- Rutinamelioratesobesitythroughbrownfatactivation:X.Yuan,etal.;FASEBJ.31,333(2016)
品牌介绍
Adipogen公司由三个子公司组成，分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国，运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发，如癌症、免疫、炎症、代谢疾病（糖尿病、肥胖）、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外，也可提供抗体和蛋白产品，Adipogen拥有自己的化学实验室，致力于开发创新型小分子化合物。
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