脂肪原/盐酸Ruboxistaurin/SYN-1172-M005/5 mg
商品编号：
SYN-1172-M005
品牌：
Adipogen Inc
市场价：
¥5940.00
美元价：
3564.00
产品分类：
其他试剂
公司分类：
Other_reagents
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| Product Details | |
|---|---|
| Synonyms | LY333531 |
| Product Type | Chemical |
| Properties | |
| Formula | C28H28N4O3 . HCl |
| MW | 468.5 . 36.5 |
| CAS | 169939-93-9 |
| Purity Chemicals | ≥95% |
| Appearance | Solid. |
| Solubility | Soluble in DMSO. |
| Declaration | Manufactured by SynKinase. |
| Other Product Data |
Target: PKC | Kinase Group: AGC | Substrate: Serine-Threonine Click here for Original Manufacturer Product Datasheet Our product description may differ slightly from the original manufacturers product datasheet. |
| InChi Key | NYQIEYDJYFVLPO-FERBBOLQSA-N |
| Shipping and Handling | |
| Shipping | AMBIENT |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Use/Stability | Stable for at least 2 years after receipt when stored at -20°C. |
| Documents | |
| MSDS |
 Download PDF |
| Product Specification Sheet | |
| Datasheet |
Download PDF |
LY333531 is a potent, selective inhibitor of Protein Kinase C isozymes, PKCβI (IC(50) of 4.7nM) and PKCβII (IC(50) of 5.9nM).
Product References
- (S)-13-[(dimethylamino)methyl]-10,11,14,15-tetrahydro-4,9:16, 21-dimetheno-1H, 13H-dibenzo[e,k]pyrrolo[3,4-h][1,4,13]oxadiazacyclohexadecene-1,3(2H)-d ione (LY333531) and related analogues: isozyme selective inhibitors of protein kinase C beta: M.R. Jirousek, et al.; J. Med. Chem. 39, 2664 (1996)
- Effects of protein kinase C inhibitors on thromboxane production by thrombin-stimulated platelets: G.P. Samokhin, et al.; Eur. J. Pharmacol. 386, 297 (1999)
- Acyclic N-(azacycloalkyl)bisindolylmaleimides: isozyme selective inhibitors of PKCbeta: M.M. Faul, et al.; Bioorg. Med. Chem. Lett. 13, 1857 (2003)
品牌介绍
Adipogen公司由三个子公司组成，分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国，运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发，如癌症、免疫、炎症、代谢疾病（糖尿病、肥胖）、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外，也可提供抗体和蛋白产品，Adipogen拥有自己的化学实验室，致力于开发创新型小分子化合物。
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