Adipogen/Rosiglitazone/AG-CR1-3570-G001/1 g
商品编号：
AG-CR1-3570-G001
品牌：
Adipogen Inc
市场价：
¥7800.00
美元价：
4680.00
产品分类：
其他试剂
公司分类：
Other_reagents
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| ProductDetails | |
|---|---|
| Synonyms | BRL49653;HSDB7555;TDZ01 |
| ProductType | Chemical |
| Properties | |
| Formula | C18H19N3O3S |
| MW | 357.4 |
| MerckIndex | 14:8265 |
| CAS | 122320-73-4 |
| PurityChemicals | ≥98%(HPLC) |
| Appearance | Whitetooff-whitepowder. |
| Solubility | SolubleinDMSO,ethanolormethanol. |
| Identity | DeterminedbyIRand1H-NMR. |
| InChiKey | YASAKCUCGLMORW-UHFFFAOYSA-N |
| ShippingandHandling | |
| Shipping | AMBIENT |
| ShortTermStorage | +4°C |
| LongTermStorage | +4°C |
| Use/StABIlity | Stableforatleast2yearsafterreceiptwhenstoredat+4°C. Stocksolutionsarestableforatleast3monthswhenstoredat-20°C. |
| Documents | |
| MSDS |  DownloadPDF |
| ProductSpecificationSheet | |
| Datasheet | DownloadPDF |
- Antidiabetic,hypoglycemicagent[1,5].
- Potentandselectiveperoxisomeproliferator-activatedreceptorγ(PPAR-γ)agoNIST[2,3].
- PotentinsulinsensitizingagentbindingtothePPARreceptorsinfatcellsandmakingthecellsmoreresponsivetoinsulin.Amelioratesinsulinresistance[4-6,8].
- Improvesbloodpressureandvascularfunction[7].
- EnhancesproliferationofendogenousneuralProgenitorcells(NPCs)[9].
- Anti-inflammatorycompound[10,11].
- Hascontroversialtherapeuticeffectsonthecardiovascularsystem[12].
- PromotesADIpocytedifferentiationofmesenchymalstemcells(MSCs)[13].
ProductReferences
- [[ω-(Heterocyclylamino)alkoxy]benzyl]-2,4-thiazolidinedionesaspotentantihyperglycemicagents:B.C.Cantello,etal.;J.Med.Chem.37,3977(1994)
- Anantidiabeticthiazolidinedioneisahighaffinityligandforperoxisomeproliferator-activatedreceptorγ(PPARγ):J.M.Lehmann,etal.; J.Biol.Chem.270,12953(1995)
- Rosiglitazone:J.A.Balfour&G.L.Plosker;Drugs57,921(1999)(Review)
- Differentialeffectsofinsulin-sensitizerstroglitazoneandrosiglitazoneonioncurrentsinratvascularmyocytes:G.A.Knock,etal.;Eur.J.Pharmacol.368,103(1999)
- Rosiglitazone:anagentfromthethiazolidinedioneclassforthetreatmentoftype2diabetes:A.Cheng-Lai&A.Levine;HeartDis.2,326(2000)(Review)
- Rosiglitazoneinthetreatmentoftype2diabetesmellitus:acriticalreview:J.M.Malinowski&S.Bolesta;Clin.Ther.22,1151(2000)(Review)
- PPAR(gamma)agonistrosiglitazoneimprovesvascularfunctionandlowersbloodpressureinhypertensivetransgenicmice:M.J.Ryan,etal.;Hypertension3,661(2004)
- Rosiglitazone:areviewofitsuseintype2diabetesmellitus:E.D.Deeks&S.J.Keam;Drugs67,2747(2007)(Review)
- Rosiglitazoneenhancestheproliferationofneuralprogenitorcellsandinhibitsinflammationresponseafterspinalcordinjury:Q.Q.Meng,etal.;Neurosci.Lett.503,191(2011)
- Inhibitoryeffectsofrosiglitazoneonlipopolysaccharide-inducedinflammationinamurinemodelandHK-2cells:W.M.Wang,etal.;Am.J.Nephrol.34,152(2011)
- PPARγagonistrosiglitazoneamelioratesLPS-inducedinflammationinvascularsmoothmusclecellsviatheTLR4/TRIF/IRF3/IP-10signalingpathway:Y.Ji,etal.;Cytokine55,409(2011)
- PPARγactivator,rosiglitazone:Isitbeneficialorharmfultothecardiovascularsystem?S.Palee,etal.;WorldJ.Cardiol.3,144(2011)
- Rosiglitazone-inducedAdipogenesisinabonemarrowmesenchymalstemcellline:D.Wang,etal.;Biomed.Sci.Instrum.47,213(2011)
品牌介绍
Adipogen公司由三个子公司组成，分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国，运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发，如癌症、免疫、炎症、代谢疾病（糖尿病、肥胖）、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外，也可提供抗体和蛋白产品，Adipogen拥有自己的化学实验室，致力于开发创新型小分子化合物。
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