Adipogen/Ponasterone A/AG-CN2-0053-M005/5 mg
商品编号：
AG-CN2-0053-M005
品牌：
Adipogen Inc
市场价：
¥3800.00
美元价：
2280.00
产品分类：
其他试剂
公司分类：
Other_reagents
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| ProductDetails | |
|---|---|
| Synonyms | PonA;25-Deoxy-20-hydroxyecdysone;25-Deoxyecdysterone;AI3-44686;2β,3β,14α,20R,22R-Pentahydroxy-5β-cholest-7-en-6-one |
| ProductType | Chemical |
| Properties | |
| Formula | C27H44O6 |
| MW | 464.6 |
| MerckIndex | 14:7588 |
| CAS | 13408-56-5 |
| Source/HostChemicals | Semi-synthetic. |
| PurityChemicals | ≥95%(HPLC) |
| Appearance | Whitetooff-whitepowder. |
| Solubility | Solubleinaceticacid,ethanol,methanolorDMSO.Insolubleinwater. |
| Identity | Identitydeterminedby1H-and13C-NMR. |
| OtherProductData | Topreparea1mMstocksolution(1.1mM)in100%ethanol:Add2mlof100%ethanolto1mg(2µmol).Gentlymixtodissolvetheproduct(5to10min.).Donotheatsolutiontodissolvetheproduct.Storethe1mMstocksolutionat+4°Corat-20°C. |
| InChiKey | PJYYBCXMCWDUAZ-JJJZTNILSA-N |
| ShippingandHandling | |
| Shipping | AMBIENT |
| ShortTermStorage | +4°C |
| LongTermStorage | -20°C |
| Use/StABIlity | Stableforatleast2yearsafterreceiptwhenstoredat-20°C. |
| Documents | |
| MSDS |  DownloadPDF |
| ProductSpecificationSheet | |
| Datasheet | DownloadPDF |
- Amemberoftheecdysteroidfamily.
- Ecdysonereceptor(EcR)agoNIST.
- AnalogofecdysonewithsimilarpropertiestomuristeroneA.
- Functional,reliableandeconomicalsubstituteformuristeroneAasaninducerfortheecdysone-inducIBLemammalianexpressionsystem.
- Inducesexpressionofβ-galactosidasetolevelssimilartothoseobtainedwithmuristeroneAinduction.
- Potentcompoundforecdysteroidactivity.
- Insectsteroidhormoneinvolvedinregulatingmetamorphosis.
ProductReferences
- ExtractionofponasteroneAandecdysteronefrompodocarpaceaeandrelatedplants:S.Imaietal.;Steroids10,557(1967)
- Ecdysonesandanalogs:effectsondevelopmentandreproductionofinsects:W.E.Robbins,etal.;Science161,1158(1968)
- TheuptakeandreleaseofponasteroneAbytheKccelllineofDrosophilamelanogaster:C.Beckers,etal.;Mol.Cell.Endocrinol.17,51(1980)
- Pastandpresentstudieswithponasterones,thefirstinsectmoltinghormonesfromplants:K.Nakanishi;Steroids57,649(1992)
- Identificationofligandsandcoligandsfortheecdysone-regulatedgeneswitch:E.Saez,etal.;PNAS97,14512(2000)
- Mammalian5"(3")-deoxyribonucleotidase,CDNAcloning,andoverexpressionoftheenzymeinEscherichiacoliandmammaliancells:C.Rampazzo,etal.;J.Biol.Chem.275,5409(2000)
- Sustainedmammarygland-directed,ponasteroneA-inducibleexpressionintransgenicmice:C.Albanese,etal.;FASEBJ.14,877(2000)
- Theecdysoneinduciblegeneexpressionsystem:unexpectedeffectsofmuristeroneAandponasteroneAoncytokinesignalinginmammaliancells:S.Constantino,etal.;Eur.CytokineNetw.12,365(2001)
- Recentadvancesininducibleexpressionintransgenicmice:C.Albanese,etal.;Semin.Cell.Dev.Biol.13,129(2002)
- PotentandselectivepartialecdysoneagonistactivityofchromafenozideinSf9cells:T.Toya,etal.;BBRC292,1087(2002)
- DevelopmentofaponasteroneA-induciblegeneexpressionsystemforapplicationinculturedskeletalmusclecells:Y.Y.Xiao,etal.;Int.J.Biochem.Cell.Biol.35,79(2003)
- DevelopmentofaninvitroReporterGeneAssayforScreeningtheEcdysoneReceptorAgonistsinMysidCrustacean:M.Hirano,etal.;Terrapub141(2010)
品牌介绍
Adipogen公司由三个子公司组成，分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国，运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发，如癌症、免疫、炎症、代谢疾病（糖尿病、肥胖）、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外，也可提供抗体和蛋白产品，Adipogen拥有自己的化学实验室，致力于开发创新型小分子化合物。
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