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当前位置: 首页 > 产品中心 > Other_reagents > Adipogen/Podophyllotoxin/AG-CN2-0049-M100/100 mg
商品详细Adipogen/Podophyllotoxin/AG-CN2-0049-M100/100 mg
Adipogen/Podophyllotoxin/AG-CN2-0049-M100/100 mg
Adipogen/Podophyllotoxin/AG-CN2-0049-M100/100 mg
商品编号: AG-CN2-0049-M100
品牌: Adipogen Inc
市场价: ¥800.00
美元价: 480.00
产地: 美国(厂家直采)
公司:
产品分类: 其他试剂
公司分类: Other_reagents
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
MoreInformation
ProductDetails
SynonymsPodofilox;NSC24818;Podophyllinicacidlactone
ProductTypeChemical
Properties
FormulaC22H22O8
MW414.4
MerckIndex14:7546
CAS518-28-5
RTECSLZ2500000
Source/HostChemicalsIsolatedfromPodophyllumemodirhizomes.
PurityChemicals≥98%(HPLC)
AppearanceWhitetooff-whitepowder.
SolubilitySolubleinchloroform,acetone,ethylacetateorethanol.Insolubleinwater.
InChiKeyYJGVMLPVUAXIQN-LBXUKJEYSA-N
ShippingandHandling
ShippingAMBIENT
ShortTermStorage+4°C
LongTermStorage-20°C
HandlingAdviceHygroscopic.
Keepunderinertgas.
Protectfrommoisture.
Use/StABIlityStableforatleast2yearsafterreceiptwhenstoredat-20°C.
Documents
MSDSDownloadPDF
ProductSpecificationSheet
DatasheetDownloadPDF
  • Potentmicrotubuleassemblyinhibitor[1-3].
  • Anticancercompound[1-5,7].
  • Celldeathinducer[1-5,7].
  • DNAtopoisomeraseIIinhibitor.Cellcycleinhibitoratthemetaphase[2,6,8].
  • Antiviral[3,4,9]andantihelminthic[1].
ProductReferences
  1. VP16-213andpodophyllotoxin.AstudyontherelationshipbetweenchemicalstructureandBIOLOGicalactivity:J.D.Loike;CancerChemother.Pharmacol.7,103(1982)
  2. Antitumoragents.I.DNAtopoisomeraseIIinhibitoryactivityandthestructuralrelationshipofpodophyllotoxinderivativesasantitumoragents:T.Terada,etal.;Chem.Pharmacol.Bull.(Tokyo)40,2720(1992)
  3. Antineoplasticandantiviralactivitiesofpodophyllotoxinrelatedlignans:M.Gordaliza,etal.;Arch.Pharmacol.327,175(1994)
  4. Podophyllotoxin:C.Canel,etal.;Phytochemistry54,115(2000)(Review)
  5. Antitumorpropertiesofpodophyllotoxinandrelatedcompounds: M.Gordaliza,etal.;Curr.Pharm.Des.6,1811(2000)(Review)
  6. Drugsthatinhibittubulinpolymerization:theparticularcaseofpodophyllotoxinandanalogues:S.Desbene&S.Giorgi-Renault;Curr.Med.Chem.AnticancerAgents2,71(2002)(Review)
  7. Podophyllotoxinderivatives:currentsyntheticapproachesfornewanticanceragents:Y.You;Curr.Pharm.Des.11,1695(2005)(Review)
  8. Camptothecinandpodophyllotoxinderivatives:inhibitorsoftopoisomeraseIandII-mechanismsofaction,pharmacokineticsandtoxicityprofile:J.T.Hartmann&H.P.Lipp;DrugSaf.29,209(2006)(Review)
  9. Anevidence-basedreviewofmedicalandsurgicaltreatmentsofgenitalwarts:N.Scheinfeld&D.S.Lehman;Dermatol.OnlineJ.12,5(2006)
品牌介绍
Adipogen公司由三个子公司组成,分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国,运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发,如癌症、免疫、炎症、代谢疾病(糖尿病、肥胖)、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外,也可提供抗体和蛋白产品,Adipogen拥有自己的化学实验室,致力于开发创新型小分子化合物。