脂肪原/苯亚甲基海因/AG-CN2-0041-M001/1 mg
商品编号：
AG-CN2-0041-M001
品牌：
Adipogen Inc
市场价：
¥3200.00
美元价：
1920.00
产品分类：
其他试剂
公司分类：
Other_reagents
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| ProductDetails | |
|---|---|
| Synonyms | PMH;5(4-Hydroxybenzylidene)hydantoin |
| ProductType | Chemical |
| Properties | |
| Formula | C10H8N2O3 |
| MW | 204.2 |
| CAS | 80171-33-1 |
| Source/HostChemicals | Isolatedfromanunidentifedmarinesponge. |
| PurityChemicals | ≥97%(HPLC) |
| Appearance | Greenishsolid. |
| Solubility | SolubleinethanolorDMSO. |
| Identity | Determinedby1H-NMR. |
| InChiKey | UPDDIBZITPTASO-YVMONPNESA-N |
| ShippingandHandling | |
| Shipping | AMBIENT |
| ShortTermStorage | +4°C |
| LongTermStorage | -20°C |
| HandlingAdvice | Keepcoolanddry. Protectfromlight. |
| Use/StABIlity | Stableforatleast2yearsafterreceiptwhenstoredat-20°C. Storesolutionsat-20°Cinthedark. |
| Documents | |
| MSDS |  DownloadPDF |
| ProductSpecificationSheet | |
| Datasheet | DownloadPDF |
- Anticancercompound[2,3,5,6].
- Chemopreventive[2,3,5,6,7].
- Showsanti-metastaticactivityinprostatecancercellsthroughenhancementofcell-celladhesion[2,3].
- Anti-invasivecompound[5,6,7].
- Glycogensynthasekinase-3β(GSK-3β)inhibitor[4].
ProductReferences
- Thesynthesisofamino-acids:Piperidineanddiethylamineascatalystsinthecondensationofaromaticaldehydeswithhydantoins:W.J.Boyd&W.Robson;Biochem.J.29,542(1935)
- Identificationofasmallmoleculeclasstoenhancecell-celladhesionandattenuateprostatetumorgrowthandmetastasis:G.V.Shah,etal.;Mol.CancerTher.8,509(2009)
- Discovery,design,andsynthesisofanti-metastaticleadphenylmethylenehydantoinsinspiredbymarinenaturalproducts:M.Mudit,etal.;Bioorg.Med.Chem.17,1731(2009)
- Themarinenatural-derivedinhibitorsofglycogensynthasekinase-3betaphenylmethylenehydantoins:Invitroandinvivoactivitiesandpharmacophoremodeling:M.A.Khanfar,etal.;Bioorg.Med.Chem.17,6032(2009)
- Phenylmethylenehydantoinsasprostatecancerinvasionandmigrationinhibitors.CoMFAapproachandQSARanalysis:M.A.Khanfar&K.A.ElSayed;Eur.J.Med.Chem.45,5397(2010)
- Phenyl-methylenehydantoinsalterCD44-specificligandbindingofbenignandmalignantprostatecellsandsuppressCD44isoformexpression:K.Yang,etal.;Am.J.Transl.Res.2,88(2010)
- MethodsforevaluationofstructuralandBIOLOGicalpropertiesofantiinvasivenaturalproducts:M.Mudit,etal.;Meth.Mol.Biol.716,55(2011)
品牌介绍
Adipogen公司由三个子公司组成，分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国，运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发，如癌症、免疫、炎症、代谢疾病（糖尿病、肥胖）、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外，也可提供抗体和蛋白产品，Adipogen拥有自己的化学实验室，致力于开发创新型小分子化合物。
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