Adipogen/Pentabromopseudilin/BVT-0441-M005/5 mg
商品编号：
BVT-0441-M005
品牌：
Adipogen Inc
市场价：
¥14400.00
美元价：
8640.00
产品分类：
其他试剂
公司分类：
Other_reagents
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| ProductDetails | |
|---|---|
| Synonyms | Pentabrompseudilin;NSC641543;NSC288032;PBQ;2-(3,5-Dibromo-2-hydroxyphenyl)-3,4,5-tribromopyrrol;2,4-Dibromo-6-(3,4,5-tribromo-1H-pyrrol-2-yl)phenol |
| ProductType | Chemical |
| Properties | |
| Formula | C10H4Br5NO |
| MW | 553.7 |
| CAS | 10245-81-5 |
| RTECS | SK8150000 |
| Source/HostChemicals | IsolatedfromseawaterproteobacteriaAlteromonasIuteo-violaceus. |
| PurityChemicals | ≥98%(HPLC) |
| Appearance | Off-whitepowder. |
| Solubility | SolubleinDMSO(5mg/ml),acetone,butanol,ethylacetateordiethylether. |
| Identity | Determinedby1H-NMR. |
| Declaration | ManufacturedbyBioViotica. |
| InChiKey | LXMNWKJHYOZUQL-UHFFFAOYSA-N |
| ShippingandHandling | |
| Shipping | BLUEICE |
| ShortTermStorage | +4°C |
| LongTermStorage | -20°C |
| HandlingAdvice | Keepcoolanddry. Protectfromlight. |
| Use/StABIlity | Stableforatleast1yearafterreceiptwhenstoredat-20°C. Storesolutionsat-20°Cinthedark. |
| Documents | |
| MSDS |  DownloadPDF |
| ProductSpecificationSheet | |
| Datasheet | DownloadPDF |
- Antibiotic[1,2,4,6].
- Antibacterial,cytotoxic,herbicidalandantimalarialcompound[3,9,11,13].
- Humanlipoxygenaseinhibitor[7].
- PotentmyosinATPaseinhibitor[8,10,14].
- Inhibitorofthenon-mevalonatepathwayenzymeIspD[13].
ProductReferences
- Productionofapyrroleantibioticbyamarinebacterium:P.R.Burkholder,etal.;Appl.Microbiol.14,649(1966)
- Thestructureofabromine-richmarineantibiotic:F.M.Lovell;JACS88,4510(1966)
- Marinebacteria.I.Synthesisofpentabromopseudilin,acytotoxicphenylpyrrolefromAlteromonasluteoviolaceus:H.LAATsch&H.Pudleiner;LiebigsAnn.Chem.9,863(1989)
- Biosynthesisofthemarineantibioticpentabromopseudilin.Part1.Thebenzenering:U.Hanefeld,etal.;J.Org.Chem.8,847(1993)
- Structure-activityrelationshipsofphenyl-andbenzoylpyrroles:H.Laatsch,etal.;Chem.Pharm.Bull.43,537(1995)
- Biosynthesisofthemarineantibioticpentabromopseudilin.Part2.Thepyrrolering:J.Peschke,etal.;Biosci.Biotechnol.Biochem.69,628(2005)
- Arev(V)-catalysedC-Nbond-formingroutetohumanlipoxygenaseinhibitors:O.Rachana,etal.;Org.Lett.7,2501(2005)
- Themechanismofpentabromopseudilininhibitionofmyosinmotoractivity:R.Fedorov,etal.;Nat.Struct.Mol.Biol.16,80(2009)
- HighlybrominatedantimicrobialmetabolitesfromamarinePseudoalteromonassp.:D.Feher,etal.;J.Nat.Prod.73,1963(2010)
- InhibitionofmyosinATPaseactivitybyhalogenatedpseudilins:astructure-activitystudy:M.Preller,etal.;J.Med.Chem.54,3675(2011)
- AgRochemicalsagainstmalaria,sleepingsickness,leishmaniasisandchagasDisease:M.Witschel,etal.;PLoSNegl.Trop.Dis.6,1805(2012)
- ToxicityofbioactiveandprobioticmarinebacteriaandtheirsecondarymetabolitesinArtemiasp.andCaenorhaBDitiselegansaseukaryoticmodelorganisms:A.K.Neu,etal.;Appl.Environ.Microbiol.80,146(2014)
- Pseudilins:halogenated,allostericinhibitorsofthenon-mevalonatepathwayenzymeIspD:A.Kunfermann,etal.;Angew.Chem.Int.Ed.Engl.53,2235(2014)
- Myosin-II-mediatedcellshapechangesandcellintercalationcontributetoprimitivestreakformation:E.Rozbicki,etal.;Nat.CellBiol.17,397(2015)
品牌介绍
Adipogen公司由三个子公司组成，分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国，运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发，如癌症、免疫、炎症、代谢疾病（糖尿病、肥胖）、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外，也可提供抗体和蛋白产品，Adipogen拥有自己的化学实验室，致力于开发创新型小分子化合物。
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