Adipogen/Papaverine . hydrochloride/AG-CN2-0414-G001/1 g
商品编号：
AG-CN2-0414-G001
品牌：
Adipogen Inc
市场价：
¥400.00
美元价：
240.00
产品分类：
其他试剂
公司分类：
Other_reagents
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| Product Details | |
|---|---|
| Synonyms | 6,7-Dimethoxy-1-veratrylisoquinoline; NSC 35443; NCI-C56359 |
| Product Type | Chemical |
| Properties | |
| Formula | C20H21NO4 . HCl |
| MW | 339.4 . 36.5 |
| CAS | 61-25-6 |
| RTECS | NW8575000 |
| Source/Host Chemicals | Synthetic. Originally isolated from Papaver somniferum. |
| Purity Chemicals | ≥95% (NMR) |
| Appearance | White to off-white crystalline powder. |
| Solubility | Soluble in DMSO, ethanol or dimethylformamide. Sparingly soluble in water. |
| Identity | Identity determined by 1H-NMR. |
| InChi Key | UOTMYNBWXDUBNX-UHFFFAOYSA-N |
| Shipping and Handling | |
| Shipping | AMBIENT |
| Short Term Storage | +4°C |
| Long Term Storage | -20°C |
| Handling Advice |
Protect from light. Protect from moisture. |
| Use/Stability | Stable for at least 2 years after receipt when stored at -20°C. |
| Documents | |
| MSDS |
 Download PDF |
| Product Specification Sheet | |
| Datasheet |
Download PDF |
- Smooth muscle relaxant and vasodilator [4].
- Phosphodiesterase PDE10A inhibitor [3,5,6].
- Antiviral [1,2].
- Antipsychotic [3].
- Potential inducer of browning in WAT.
Product References
- Effect of papaverine treatment on replication of measles virus in human neural and nonneural cells: Y. Yoshikawa & K. Yamanouchi; J. Virol. 50, 489 (1984)
- Papaverine hydrochloride: effects on HIV replication and T-lymphocyte cell function: M. Nokta, et al.; Immunopharmacol. 26, 181 (1993)
- Inhibition of the striatum-enriched phosphodiesterase PDE10A: a novel approach to the treatment of psychosis: J.A. Siuciak, et al.; Neuropharmacol. 51, 386 (2006)
- The effect of papaverine on ion channels in rat basilar smooth muscle cells: D.H. Han, et al.; Neurol. Res. 29, 544 (2007)
- The PDE10A inhibitor, papaverine, differentially activates ERK in male and female rat striatal slices: Y.T. Hsu, et al.; Neuropharmacol. 61, 1275 (2011)
- PDE10 inhibition increases GluA1 and CREB phosphorylation and improves spatial and recognition memories in a huntington's disease mouse model: A. Giralt, et al.; Hippocampus 23, 684 (2013)
- A novel thermoregulatory role for PDE10A in mouse and human adipocytes: M.K. Hankir, et al.; EMBO Mol. Med. 8, 796 (2016)
品牌介绍
Adipogen公司由三个子公司组成，分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国，运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发，如癌症、免疫、炎症、代谢疾病（糖尿病、肥胖）、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外，也可提供抗体和蛋白产品，Adipogen拥有自己的化学实验室，致力于开发创新型小分子化合物。
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