脂肪原/甲磺酸奈非那韦/SYN-3022-M050/50 mg
商品编号：
SYN-3022-M050
品牌：
Adipogen Inc
市场价：
¥5940.00
美元价：
3564.00
产品分类：
其他试剂
公司分类：
Other_reagents
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| ProductDetails | |
|---|---|
| Synonyms | AG1341 |
| ProductType | Chemical |
| Properties | |
| Formula | C32H45N3O4S.CH4O3S |
| MW | 567.8.96.1 |
| CAS | 159989-65-8 |
| PurityChemicals | ≥95% |
| Appearance | Solid. |
| Solubility | SolubleinDMSO. |
| Declaration | ManufacturedbySynKinase. |
| OtherProductData | Target:N/A|KinaseGroup:N/A|Substrate:N/A ClickhereforOriginalManufacturerProductDatasheet Ourproductdescriptionmaydifferslightlyfromtheoriginalmanufacturersproductdatasheet. |
| InChiKey | NQHXCOAXSHGTIA-SKXNDZRYSA-N |
| ShippingandHandling | |
| Shipping | AMBIENT |
| ShortTermStorage | +4°C |
| LongTermStorage | -20°C |
| Use/StABIlity | Stableforatleast2yearsafterreceiptwhenstoredat-20°C. |
| Documents | |
| MSDS | No |
| ProductSpecificationSheet | |
| Datasheet |  DownloadPDF |
Nelfinavirisananti-retroviraldrugusedinthetreatmentofthehumanimmunodeficiencyvirus(HIV).ItisapotentHIVproteaseinhibitorwithpotentantiviralactivity(95%effectivedose=0.04µg/ml)againstanumberofHIV-1strainsinacuteandchronicmodelsofinfection.Nelfinavirisaneffectiveanti-canceragent,withanEC50of3.1-5.2µMandinducedapoptosisandautophagicresponses.ItmediatesAKTsignalingdemonstratinginhibitionofendogenousandgrowthfactor-inducedAktactivation.Nelfinavirdecreasedtheviabilityofapanelofdrug-resistantbreastcancercelllinesandinhibitedthegrowthofNSCLCxenograftsthatwasassociatedwithinductionofERstress,autophagyandapoptosis.
ProductReferences
- Pharmacokineticsofciprofloxacininpediatriccysticfibrosispatients:H.G.Schaefer,etal.;Antimicrob.AgentsChemother.40,29(1996)
- PreclinicalpharmacokineticsanddistributiontotissueofAG1343,aninhibitorofhumanimmunodeficiencyvirustype1protease:B.V.Shetty,etal.;Antimicrob.AgentsChemother.40,110(1996)
- Nelfinavir,AleadHIVproteaseinhibitor,isabroad-spectrum,anticanceragentthatinducesendoplasmicreticulumstress,autophagy,andapoptosisinvitroandinvivo:J.J.Gills,etal.;Clin.CancerRes.13,5183(2007)
品牌介绍
Adipogen公司由三个子公司组成，分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国，运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发，如癌症、免疫、炎症、代谢疾病（糖尿病、肥胖）、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外，也可提供抗体和蛋白产品，Adipogen拥有自己的化学实验室，致力于开发创新型小分子化合物。
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