脂肪原/鼠甾酮A/AG-CN2-0070-M001/1 mg
商品编号：
AG-CN2-0070-M001
品牌：
Adipogen Inc
市场价：
¥2700.00
美元价：
1620.00
产品分类：
其他试剂
公司分类：
Other_reagents
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| ProductDetails | |
|---|---|
| Synonyms | 2β,3β,5β,11α,14α,20R,22R-Heptahydroxycholest-7-en-6-one |
| ProductType | Chemical |
| Properties | |
| Formula | C27H44O8 |
| MW | 496.6 |
| CAS | 38778-30-2 |
| Source/HostChemicals | IsolatedfromIpomoeahederaceaseeds. |
| PurityChemicals | ≥95%(HPLC) |
| Appearance | Whitetooff-whitesolid. |
| Solubility | Solubleinaceticacid,ethanol,methanolorDMSO.Insolubleinwater. |
| Identity | Identitydeterminedby1H-NMR. |
| OtherProductData | Topreparea1mMstocksolution(1.1mM)in100%ethanol:Add2mlof100%ethanolto1mgmuristeroneA(2µmol).Gentlymixtodissolvetheproduct(5to10min.).Donotheatsolutiontodissolvetheproduct.Storethe1mMstocksolutionat+4°Corat-20°C. |
| InChiKey | LRJUYAVTHIEHAI-LDJCFVSYSA-N |
| ShippingandHandling | |
| Shipping | AMBIENT |
| ShortTermStorage | +4°C |
| LongTermStorage | -20°C |
| Use/StABIlity | Stableforatleast2yearsafterreceiptwhenstoredat-20°C. |
| Documents | |
| MSDS |  DownloadPDF |
| ProductSpecificationSheet | |
| Datasheet | DownloadPDF |
- Potentmemberoftheecdysteroidfamily.
- Ecdysonereceptor(EcR)agoNIST.
- AnalogofecdysonewithsimilarpropertiestoponasteroneA(Prod.No.AG-CN2-0053).
- Inducerofecdysone-inducIBLegeneexpressionsystemsinmammaliancellsandtransgenicanimals.
- Inducesapoptosisincellstransfectedwithwild-typeBax.
- Inducesexpressionofβ-galactosidase.
- StimulatesBcl-XLmRNAtranscriptionandinhibitsTRAIL-andhFasL-inducedapoptosisinRKOcells.
- Insectsteroidhormoneinvolvedinregulatingmetamorphosis,causingaresponsetoG2cellcyclearrest.
- Majormoltinghormoneinsomeinsects.Hasprotectiveeffectsinplants.
ProductReferences
- StructureofmuristeroneA,anewphytoecdysone:L.Canonica,etal.;J.C.S.Chem.Commun.1060(1972)
- Newphytoecdysonesfromkaladana.I.StructureofmuristeroneAandkaladasterone:L.Canonica,etal.;Gazz.Chim.Ital.107,123(1977)
- CharacterizationandpartialpurificationoftheDrosophilaKccellecdysteroidreceptor:T.M.Landon,etal.;J.Biol.Chem.263,4693(1988)
- Ecdysteroid-DependentRegulationofGenesinMammalianCellsbyaDrosophilaEcdysoneReceptorandChimericTransactivators:K.Christopherson,etal.;PNAS89,6314(1992)
- Ecdysone-induciblegeneexpressioninmammaliancellsandtransgenicmice:D.No,etal.;PNAS93,3346(1996)
- TheoverexpressionofBaxproducescelldeathuponinductionofthemitochondrialpermeabilitytransition:J.G.Pastorino,etal.;J.Biol.Chem.273,7770(1998)
- ImpairmentoftheproapoptoticactivityofBaxbymissensemutationsfoundingastrointestinalcancers:J.Gil,etal.;CancerRes.59,2034(1999)
- Identificationofligandsandcoligandsfortheecdysone-regulatedgeneswitch:E.Saez,etal.;PNAS97,14512(2000)
- EctopicexpressionofcyclinD1impairstheproliferationandenhancestheapoptosisofamurinelymphoidcellline:F.Duquesne,etal.;CellDeathDiffer.8,51(2001)
- Theecdysoneinduciblegeneexpressionsystem:unexpectedeffectsofmuristeroneAandponasteroneAoncytokinesignalinginmammaliancells:S.Constantino,etal.;Eur.CytokineNetw.12,365(2001)
- MuristeroneA-inducednervegrowthfactorreleasefromgeneticallyengineeredhumandermalfibroblastsforperipheralnervetissueengineering: C.W.Patrick,etal.;TissueEng.7,303(2001)
- Agonistsofanecdysone-induciblemammalianexpressionsysteminhibitFas-ligand-andTRAIL-inducedapoptosisinthehumancoloncarcinomacelllineRKO:IOehme,etal.; CellDeathDiff.13,189(2005)
- Selectedtechnologiestocontrolgenesandtheirproductsforexperimentalandclinicalpurposes:H.K.Alexander,etal.;Arch.Immunol.Ther.Exp. 55,139(2007)(Review)
品牌介绍
Adipogen公司由三个子公司组成，分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国，运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发，如癌症、免疫、炎症、代谢疾病（糖尿病、肥胖）、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外，也可提供抗体和蛋白产品，Adipogen拥有自己的化学实验室，致力于开发创新型小分子化合物。
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