Adipogen/MS-275/AG-CR1-0032-M001/1 mg
商品编号：
AG-CR1-0032-M001
品牌：
Adipogen Inc
市场价：
¥300.00
美元价：
180.00
产品分类：
其他试剂
公司分类：
Other_reagents
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| ProductDetails | |
|---|---|
| Synonyms | N-(2-Aminophenyl)-4-[N-(pyridine-3-ylmethoxy-carbonyl)aminomethyl]benzamide;MS-27-275 |
| ProductType | Chemical |
| Properties | |
| Formula | C21H20N4O3 |
| MW | 376.4 |
| CAS | 209783-80-2 |
| PurityChemicals | ≥98%(NMR) |
| Appearance | Off-whitetotansolid. |
| Solubility | SolubleinDMSOormethanol. |
| InChiKey | LTWMTJUZATWRDH-UHFFFAOYSA-N |
| ShippingandHandling | |
| Shipping | AMBIENT |
| ShortTermStorage | +4°C |
| LongTermStorage | -20°C |
| HandlingAdvice | Protectfromlight. |
| Use/StABIlity | Stableforatleast2yearsafterreceiptwhenstoredat-20°C. |
| Documents | |
| MSDS |  DownloadPDF |
| ProductSpecificationSheet | |
| Datasheet | DownloadPDF |
- HDAC1inhibitor[1,2].
- Antitumorcompound[1-3].
- Antiproliferative[2].
- TGF-βtypeIIreceptorinducer[2].
- Apoptosisinducer[4].
- Anti-inflammatory[5].
- Angiogenesisinhibitor[6].
- Review[7].
- Promoteseitherself-renewalordifferentiationofembryonicstemcells[8].
ProductReferences
- Asyntheticinhibitorofhistonedeacetylase,MS-27-275,withmarkedinvivoantitumoractivityagainsthumantumors:A.Saito,etal.;PNAS96,4592(1999)
- MS-275,ahistonedeacetylaseinhibitor,selectivelyinducestransforminggrowthfactorbetatypeIIreceptorexpressioninhumanbreastcancercells:B.I.Lee,etal.;CancerRes.61,931(2001)
- MS-27-275,aninhibitorofhistonedeacetylase,hasmarkedinvitroandinvivoantitumoractivityagainstpediatricsolidtumors:J.Jaboin,etal.;CancerRes.62,6108(2002)
- ThehistonedeacetylaseinhibitorMS-275promotesdifferentiationorapoptosisinhumanleukemiacellsthroughaprocessregulatedbygenerationofreactiveoxygenspeciesandinductionofp21CIP1/WAF11:R.R.Rosato,etal.;CancerRes.63,3637(2003)
- MS-275,anhistonedeacetylaseinhibitor,reducestheinflammatoryreactioninratexperimentalautoimmuneneuritis:Z.Y.Zhang,etal.;Neuroscience169,370(2010)
- S-275sensitizesTRAIL-resistantbreastcancercells,inhibitsangiogenesisandmetastasis,andreversesepithelial-mesenchymaltransitioninvivo:R.K.Srivastava,etal.;Mol.CancerTher.9,3254(2010)
- MS-275,apotentorallyavailableinhibitorofhistonedeacetylases--thedevelopmentofananticanceragent:H.Hess-Stumpp,etal.;Int.J.Biochem.CellBiol.39,1388(2007)
- HistoneDeacetylaseInhibitorsinCellPluripotency,Differentiation,andReprogramming:A.Kretsovali,etal.;StemCellsInt.2012,1(2012)
品牌介绍
Adipogen公司由三个子公司组成，分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国，运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发，如癌症、免疫、炎症、代谢疾病（糖尿病、肥胖）、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外，也可提供抗体和蛋白产品，Adipogen拥有自己的化学实验室，致力于开发创新型小分子化合物。
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