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当前位置: 首页 > 产品中心 > Other_reagents > Adipogen/Monosodium urate (crystals)/AG-CR1-3950-2002/2 x 2 mg
商品详细Adipogen/Monosodium urate (crystals)/AG-CR1-3950-2002/2 x 2 mg
Adipogen/Monosodium urate (crystals)/AG-CR1-3950-2002/2 x 2 mg
Adipogen/Monosodium urate (crystals)/AG-CR1-3950-2002/2 x 2 mg
商品编号: AG-CR1-3950-2002
品牌: Adipogen Inc
市场价: ¥2200.00
美元价: 1320.00
产地: 美国(厂家直采)
公司:
产品分类: 其他试剂
公司分类: Other_reagents
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
MoreInformation
ProductDetails
SynonymsMSU(crystals);Uricacid(crystals)
ProductTypeChemical
Properties
FormulaC5H3N4O3.Na
MW167.1.23.0
CAS1198-77-2
RTECSYU7062000
AppearanceSolidcrystals.SolutionmayappearasaslightlyhazysUSPension.
SolubilityNotsolubleinPBS.Reconstitute2mgofMSUin100μlPBStoobtaina20mg/mlsuspension.
EndotoxinContent<0.001eu g="" purified="" protein="" (lal="" test;="" lonza).="">
InChiKeyNAFSTSRULRIERK-UHFFFAOYSA-M
ShippingandHandling
ShippingAMBIENT
ShortTermStorage+4°C
LongTermStorage-20°C
HandlingAdviceVortexbeforeuse.
Use/StABIlityStableforatleast2yearsafterreceiptwhenstoredat-20°C.
Documents
ProtocolsDownloadPDF
MSDSDownloadPDF
ProductSpecificationSheet
DatasheetDownloadPDF
  • NLRP3/NALP3inflammasomeactivator.SpeciallycrystallizedandtestedforBIOLOGicalactivity.
  • Stimulatesthecaspase-1activatingNLRP3/NALP3inflammasome,resultingintheproductionofactiveIL-1βandIL-18.
ProductReferences
  1. Gout-associateduricacidcrystalsactivatetheNALP3inflammasome:F.Martinon,etal.;Nature440,237(2006)
  2. MalarialhemozoinactivatestheNLRP3inflammasomethroughLynandSykkinases:M.T.Shio,etal.;PLoSPathog.5,e1000559(2009)
  3. Crystalsofmonosodiumuratemonohydrateenhancelipopolysaccharide-inducedreleaseofinterleukin1betabymononuclearcellsthroughacaspase1-mediatedprocess:E.J.Giamarellos-Bourboulis,etal.;Ann.Rheum.Dis.68,273(2009)
  4. Monosodiumuratecrystalsininflammationandimmunity:Y.Shi,etal.;Immunol.Rev.233,203(2010)
  5. RIP3-mediatednecroticcelldeathacceleratessystematicinflammationandmortality:L.Meng,etal.;PNAS112,11007(2015)
  6. Calciumphosphateparticlesstimulateinterleukin-1βreleasefromhumanvascularsmoothmusclecells:Aroleforspleentyrosinekinaseandexosomerelease:Y.Dautova,etal.;J.Mol.CellCardiol.aheadofprint(2017)
品牌介绍
Adipogen公司由三个子公司组成,分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国,运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发,如癌症、免疫、炎症、代谢疾病(糖尿病、肥胖)、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外,也可提供抗体和蛋白产品,Adipogen拥有自己的化学实验室,致力于开发创新型小分子化合物。