
Adipogen/Monosodium urate (crystals)/AG-CR1-3950-2002/2 x 2 mg
商品编号:
AG-CR1-3950-2002
品牌:
Adipogen Inc
市场价:
¥2200.00
美元价:
1320.00
产品分类:
其他试剂
公司分类:
Other_reagents
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
ProductDetails | |
---|---|
Synonyms | MSU(crystals);Uricacid(crystals) |
ProductType | Chemical |
Properties | |
Formula | C5H3N4O3.Na |
MW | 167.1.23.0 |
CAS | 1198-77-2 |
RTECS | YU7062000 |
Appearance | Solidcrystals.SolutionmayappearasaslightlyhazysUSPension. |
Solubility | NotsolubleinPBS.Reconstitute2mgofMSUin100μlPBStoobtaina20mg/mlsuspension. |
EndotoxinContent | <0.001eu g="" purified="" protein="" (lal="" test;="" lonza).="">0.001eu> |
InChiKey | NAFSTSRULRIERK-UHFFFAOYSA-M |
ShippingandHandling | |
Shipping | AMBIENT |
ShortTermStorage | +4°C |
LongTermStorage | -20°C |
HandlingAdvice | Vortexbeforeuse. |
Use/StABIlity | Stableforatleast2yearsafterreceiptwhenstoredat-20°C. |
Documents | |
Protocols | ![]() |
MSDS | ![]() |
ProductSpecificationSheet | |
Datasheet | ![]() |
- NLRP3/NALP3inflammasomeactivator.SpeciallycrystallizedandtestedforBIOLOGicalactivity.
- Stimulatesthecaspase-1activatingNLRP3/NALP3inflammasome,resultingintheproductionofactiveIL-1βandIL-18.
ProductReferences
- Gout-associateduricacidcrystalsactivatetheNALP3inflammasome:F.Martinon,etal.;Nature440,237(2006)
- MalarialhemozoinactivatestheNLRP3inflammasomethroughLynandSykkinases:M.T.Shio,etal.;PLoSPathog.5,e1000559(2009)
- Crystalsofmonosodiumuratemonohydrateenhancelipopolysaccharide-inducedreleaseofinterleukin1betabymononuclearcellsthroughacaspase1-mediatedprocess:E.J.Giamarellos-Bourboulis,etal.;Ann.Rheum.Dis.68,273(2009)
- Monosodiumuratecrystalsininflammationandimmunity:Y.Shi,etal.;Immunol.Rev.233,203(2010)
- RIP3-mediatednecroticcelldeathacceleratessystematicinflammationandmortality:L.Meng,etal.;PNAS112,11007(2015)
- Calciumphosphateparticlesstimulateinterleukin-1βreleasefromhumanvascularsmoothmusclecells:Aroleforspleentyrosinekinaseandexosomerelease:Y.Dautova,etal.;J.Mol.CellCardiol.aheadofprint(2017)
品牌介绍
Adipogen公司由三个子公司组成,分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国,运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发,如癌症、免疫、炎症、代谢疾病(糖尿病、肥胖)、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外,也可提供抗体和蛋白产品,Adipogen拥有自己的化学实验室,致力于开发创新型小分子化合物。
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