Adipogen/MnTBAP chloride/AG-CR1-0133-M050/50 mg
商品编号：
AG-CR1-0133-M050
品牌：
Adipogen Inc
市场价：
¥1300.00
美元价：
780.00
产品分类：
其他试剂
公司分类：
Other_reagents
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| ProductDetails | |
|---|---|
| Synonyms | Manganese(III)tetrakis(4-benzoicacid)porphyrinchloride |
| ProductType | Chemical |
| Properties | |
| Formula | C48H28MnN4O8Cl |
| MW | 879.2 |
| CAS | 55266-18-7 |
| PurityChemicals | ≥97% |
| Appearance | Blackcrystallinepowder. |
| Solubility | Dissolveat0.1Minaqueousbase,thenaddbuffertolowerpHtopH7.0orhigherasneeded. |
| InChiKey | APHAGHGOUIMDLD-SAHKUQKESA-M |
| ShippingandHandling | |
| Shipping | AMBIENT |
| ShortTermStorage | +4°C |
| LongTermStorage | -20°C |
| Use/StABIlity | Stableforatleast2yearsafterreceiptwhenstoredat-20°C. |
| Documents | |
| MSDS |  DownloadPDF |
| ProductSpecificationSheet | |
| Datasheet | DownloadPDF |
- Cellpermeablesuperoxidedismutase(SOD)mimetic[1,2].
- Potentinhibitorofperoxynitrite-inducedoxidativereactions(peroxynitritescavenger),butnotascavengerofnitricoxide(NO)[3].
- Neuronalapoptosisinhibitor[4].
- ProtectsTcellsfromsuperoxidegeneration,caspase-dependentDNAlossandcelldeath[5].
- Lipopolysaccharide-inducedTNF-αproductioninhibitor,bypreventionofintracellularROSgenerationandsubsequentinactivationofp38MAPKandSAPK/JNK[6].
.
ProductReferences
- StableMn(III)porphyrinsmimicsuperoxidedismutaseinvitroandsubstituteforitinvivo:K.M.Faulkner,etal.;J.Biol.Chem. 269,23471(1994)
- Ametalloporphyrinsuperoxidedismutasemimeticprotectsagainstparaquat-inducedendothelialcellinjury,invitro:B.J.Day,etal.;J.Pharm.Exp.Ther.275,1227(1995)
- Evaluationoftherelativecontributionofnitricoxideandperoxynitritetothesuppressionofmitochondrialrespirationinimmunostimulatedmacrophagesusingamanganesemesoporphyrinsuperoxidedismutasemimeticandperoxynitritescavenger:C.Szabe;,etal.;FEBSLett.381,82(1996)
- Inhibitionofneuronalapoptosisbyametalloporphyrinsuperoxidedismutasemimic:M.Patel;J.NeuRochem.71,1068(1998)
- Reactiveoxygenspeciesregulateactivation-inducedTcellapoptosis:D.A.Hildeman,etal.;Immunity10,735(1999)
- MnTBAP,asyntheticmetalloporphyrin,inhibitsproductionoftumornecrosisfactor-alphainlipopolysaccharide-stimulatedRAW264.7macrophagescellsviainhibitingoxidativestress-mediatingp38andSAPK/JNKsignaling:G.Tumurkhuu,etal.;FEMSImmunol.Med.Microbiol.49,304(2007)
- RegulationofBeclin1proteinphosphorylationandautophagybyproteinphosphatase2A(PP2A)anddeath-associatedproteinkinase3(DAPK3):N.Fujiwara,etal.;J.Biol.Chem.291,10858(2016)
品牌介绍
Adipogen公司由三个子公司组成，分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国，运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发，如癌症、免疫、炎症、代谢疾病（糖尿病、肥胖）、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外，也可提供抗体和蛋白产品，Adipogen拥有自己的化学实验室，致力于开发创新型小分子化合物。
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