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商品详细Adipogen/Meleagrin/AG-CN2-0451-M001/1 mg
Adipogen/Meleagrin/AG-CN2-0451-M001/1 mg
Adipogen/Meleagrin/AG-CN2-0451-M001/1 mg
商品编号: AG-CN2-0451-M001
品牌: Adipogen Inc
市场价: ¥3900.00
美元价: 2340.00
产地: 美国(厂家直采)
公司:
产品分类: 其他试剂
公司分类: Other_reagents
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
More Information
Product Details
Synonyms 6-O-Methyloxaline
Product Type Chemical
Properties
Formula C23H23N5O4
MW 433.5
CAS 71751-77-4
Source/Host Chemicals Isolated from Penicillium sp.
Purity Chemicals ≥90% (HPLC)
Appearance Yellow adhered film.
Solubility Soluble in DMSO or ethanol.
InChi Key JTJJJLSLKZFEPJ-ZAYCRUKZSA-N
Shipping and Handling
Shipping AMBIENT
Short Term Storage +4°C
Long Term Storage -20°C
Handling Advice Protect from light.
Protect from moisture.
Use/Stability Stable for at least 2 years after receipt when stored at -20°C.
Documents
MSDS Download PDF
Product Specification Sheet
Datasheet Download PDF
  • Mycotoxin.
  • Alkaloid antibiotic.
  • Bacterial enoyl-acyl carrier protein reductase (FabI) inhibitor.
  • Antineoplastic activity.
  • Moderate cytotoxicity against A-549 and HL-60 cell lines. Induces cell cycle arrest through G2/M phase, presumably by inhibiting tubulin polymerization.
  • Antifouling agent against the barnacle Balanus amphitrite.
Product References
  1. Studies on fungal products. VII. The structures of meleagrin and 9-O-p-bromobenzoylmeleagrin: K. Kawai, et al.; Chem. Pharm. Bull. 32, 94 (1984)
  2. Study of the alkaloid composition of the food-infecting penicilles: T.A. Reshetilova, et al.; Food Addit. Contam. 12, 461 (1995)
  3. Production of mycotoxins on artificially and naturally infested building materials: K.F. Nielsen, et al.; Mycopathologia 145, 43 (1999)
  4. Alkaloids from a deep ocean sediment-derived fungus Penicillium sp. and their antitumor activities: L. Du, et al.; J. Antibiot. 63, 165 (2010)
  5. iTRAQ-based proteomic profiling of the barnacle Balanus amphitrite in response to the antifouling compound meleagrin: Z. Han, et al.; J. Proteome Res. 12, 2090 (2013)
  6. Meleagrin, a new FabI inhibitor from Penicillium chryosogenum with at least one additional mode of action: C.J. Zheng, et al.; PLoS One 8, e78922 (2013)
品牌介绍
Adipogen公司由三个子公司组成,分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国,运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发,如癌症、免疫、炎症、代谢疾病(糖尿病、肥胖)、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外,也可提供抗体和蛋白产品,Adipogen拥有自己的化学实验室,致力于开发创新型小分子化合物。