
Adipogen/MEGA-8 (ultrapure)/AG-CC1-0007-G001/1 g
商品编号:
AG-CC1-0007-G001
品牌:
Adipogen Inc
市场价:
¥1500.00
美元价:
900.00
产品分类:
其他试剂
公司分类:
Other_reagents
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
ProductDetails | |
---|---|
Synonyms | N-Octanoyl-N-methylglucamine;OMEGA |
ProductType | Chemical |
Properties | |
Formula | C15H31NO6 |
MW | 321.4 |
CAS | 85316-98-9 |
PurityChemicals | >99%(HPLC) |
Appearance | Whitecrystallinepowder. |
Solubility | Solubleinwater(>2g/10mlat20°C). |
OtherProductData | Thephospholipidbilayeristhebasicstructureofthecellmembrane.Inmembranebiochemistryresearch,membraneproteinsaresolubilizedandpurifiedtostudytheirstructureandfunction.Proteinsboundtocellmembraneshavehydrophobicsitesburiedwithinthephospholipidbilayersandhydrophilicsitesfacingtowardthewaterlayer.Detergentsareusedtoisolatelargeinsolublemoleculessuchasproteins.Detergentsinteractwiththehydrophobicsitesofproteins,whicharethensolubilizedinthewaterlayer,thusseparatingmembraneproteins.Itisimportanttochooseadetergentthatdoesnotdisruptthebioactivitiesoftargetproteins. Adetergentrequiresthefollowingcharacteristicstobesuitableforisolationofmembraneproteins:SufficientproteinsolubilizationcapABIlity.|Nodenaturingorinactivationofproteins.|Nointerferencewithproteinactivities.|Noprecipitationat4°C.|Appropriatecriticalmicelleconcentrations(CMC)andmicellesize.|NoabsorptionintheUVregion.|Notoxicity.|Availabilityofdetergentdetectionmethods.|Non-ionicdetergentifionexchangechromatographyisused. |
InChiKey | SBWGZAXBCCNRTM-UHFFFAOYSA-N |
ShippingandHandling | |
Shipping | AMBIENT |
ShortTermStorage | +4°C |
LongTermStorage | -20°C |
HandlingAdvice | Keepcoolanddry. Protectfrommoisture. |
Use/Stability | Stableforatleast2yearsafterreceiptwhenstoredat-20°C. |
Documents | |
MSDS | ![]() |
ProductSpecificationSheet | |
Datasheet | ![]() |
- Non-ionicwater-solubledetergentwithnondenaturingproperties.
- TransparentintheUVregion.
- Relativelyhighcriticalmicelleconcentration(CMC)value(79mM/l).
- Idealforstudyingtheconformationandfunctionofproteins,keepingthesecondaryandtertiarystructureintact,thereforesuitedforsolubilizingmembraneproteinswithoutalteringBIOLOGicalactivity.Efficientlyseparateshydrophilicproteinsfrommembranespanning,hydrophobicproteins.Idealforuseasmembraneproteinsolubilizer.
ProductReferences
- Thestructuresof1-deoxy-(N-methyloctanamido)-D-glucitol(MEGA-8)and1-deoxy-(N-methylundecanamido)-D-glucitol(MEGA-11):G.A.Jeffrey&H.Maluszynska;ActaCrystallogr.B45,447(1989)
- Solubilitypropertiesofthealkylmethylglucamidesurfactants:A.Walter,etal.;Biochim.Biophys.Acta1029,67(1990)
- Differentialsolubilizationoflipidsalongwithmembraneproteinsbydifferentclassesofdetergents:P.Banerjee,etal.;Chem.Phys.Lipids77,65(1995)
- SaltEffectonCriticalMicelleConcentrationsofNonionicSurfactants,N-Acyl-N-methylglucamides(MEGA-n):S.Miyagishi,etal.;J.ColloidInterfaceSci.238,91(2001)
- Blendingeffectsonadsorptionandmicellizationofdifferentmembraneproteinsolubilizers:aThermodynamicstudyonthreemixedsystemsofCHAPSwithMEGA-8,-9and-10inpH7.2phosphatebuffersolution:J.S.Ko,etal.;ColloidsSurf.BBiointerfaces45,90(2005)
品牌介绍
Adipogen公司由三个子公司组成,分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国,运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发,如癌症、免疫、炎症、代谢疾病(糖尿病、肥胖)、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外,也可提供抗体和蛋白产品,Adipogen拥有自己的化学实验室,致力于开发创新型小分子化合物。
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