Adipogen/Me6BIO/AG-MR-C0021-M025/25 mg
商品编号：
AG-MR-C0021-M025
品牌：
Adipogen Inc
市场价：
¥6000.00
美元价：
3600.00
产品分类：
其他试剂
公司分类：
Other_reagents
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| ProductDetails | |
|---|---|
| Synonyms | MeBIO;1-Methyl-6-bromo-indirubin-3"-oxime |
| ProductType | Chemical |
| Properties | |
| Formula | C17H12BrN3O2 |
| MW | 370.2 |
| CAS | 667463-95-8 |
| PurityChemicals | ≥95%(NMR) |
| Appearance | Darkredsolid. |
| Solubility | SolubleinDMSOorethanol. |
| Reconstitution | Stocksolutionscanbemadeupto10mMinDMSO. |
| Identity | Determinedby1H-NMR. |
| InChiKey | JUKQKURGZYNHFN-NVVUQHMZSA-N |
| ShippingandHandling | |
| Shipping | AMBIENT |
| ShortTermStorage | +4°C |
| LongTermStorage | -20°C |
| HandlingAdvice | Keepcoolanddry. Protectfromlightandmoisture. |
| Use/StABIlity | Stableforatleast2yearsafterreceiptwhenstoredat-20°C. |
| Documents | |
| MSDS |  DownloadPDF |
| ProductSpecificationSheet | |
| Datasheet | DownloadPDF |
- N-methylatedinactivecontrolanalogof6-bromoindirubin-3"-oxime(6BIO)(Prod.No.MR-C0019).
- DisplaysminimalactivityagainstCDK1/CyclinB,GSK-3α/βandCDK5/p25.
- Arylhydrocarbonreceptor(AhR)agoNIST;causesredistributionofAhRtothenucleus.
ProductReferences
- GSK-3-selectiveinhibitorsderivedfromTyrianpurpleindirubins:L.Meijer,etal.;Chem.Biol.10,1255(2003)
- Structuralbasisforthesynthesisofindirubinsaspotentandselectiveinhibitorsofglycogensynthasekinase-3andcyclin-dependentkinases:P.Polychronopoulos,etal.;J.Med.Chem.47,935(2004)
- Independentactionsoncyclin-dependentkinasesandarylhydrocarbonreceptormediatetheantiproliferativeeffectsofindirubins:M.Knockaert,etal.;Oncogene23,4400(2004)
- TheGSK-3inhibitorBIOpromotesproliferationinmammaliancardiomyocytes:A.S.Tseng,etal.;Chem.Biol.13,957(2006)
- Indirubin,theredshadeofindigo:L.Meijer,etal.(Editors):In«LifeinProgress»,StationBIOLOGique,Roscoff,297pp.(2006)
- Indirubinsdecreasegliomainvasionbyblockingmigratoryphenotypesinboththetumorandstromalendothelialcellcompartments:S.P.Williams,etal.;CancerRes.71,5374(2011)
- Pleiotrophinsuppressionofreceptorproteintyrosinephosphatase-β/ζmaintainstheself-renewalcompetenceoffetalhumanoligodendrocyteProgenitorcells:C.R.McClain,etal.;J.Neurosci.32,15066(2012)
品牌介绍
Adipogen公司由三个子公司组成，分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国，运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发，如癌症、免疫、炎症、代谢疾病（糖尿病、肥胖）、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外，也可提供抗体和蛋白产品，Adipogen拥有自己的化学实验室，致力于开发创新型小分子化合物。
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