Adipogen/MBP146-78/SYN-1227-M050/50 mg
商品编号：
SYN-1227-M050
品牌：
Adipogen Inc
市场价：
¥11880.00
美元价：
7128.00
产品分类：
其他试剂
公司分类：
Other_reagents
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
| ProductDetails | |
|---|---|
| Synonyms | 4-[2-(4-Fluorophenyl)-5-(1-methylpiperidine-4-yl)-1H-pyrrol-3-yl]pyridine |
| ProductType | Chemical |
| Properties | |
| Formula | C21H22FN3 |
| MW | 335.4 |
| CAS | 188343-77-3 |
| PurityChemicals | ≥95%(HPLC) |
| Appearance | Solid. |
| Solubility | SolubleinDMSO. |
| Declaration | ManufacturedbySynKinase. |
| OtherProductData | Target:PKG|KinaseGroup:AGC|Substrate:Serine-Threonine ClickhereforOriginalManufacturerProductDatasheet Ourproductdescriptionmaydifferslightlyfromtheoriginalmanufacturersproductdatasheet. |
| InChiKey | RBWNFHXBUDPAIO-UHFFFAOYSA-N |
| ShippingandHandling | |
| Shipping | AMBIENT |
| ShortTermStorage | +4°C |
| LongTermStorage | -20°C |
| Use/StABIlity | Stableforatleast2yearsafterreceiptwhenstoredat-20°C. |
| Documents | |
| MSDS | No |
| ProductSpecificationSheet | |
| Datasheet |  DownloadPDF |
MBP146-78inhibitsthegrowthofEimeriaspp.bothinvitroandinvivo.ThemoleculartargetofMBP146-78wasidentifiedascGMP-dependentproteinkinase(PKG)usingatritiatedanaloguetopurifyaapproximately120-kDaproteinfromlysatesofEimeriatenella.ThisrepresentsthefirstexampleofaprotozoalPKG.MBP146-78isapotentinhibitorofbothsolubleandmembrane-associatedisoformsofnativePKG,aswellasrecombinantenzyme,withanIC50of<1nm.
ProductReferences
- PurificationandmolecularcharacterizationofcGMP-dependentproteinkinasefromApicomplexanparasites.Anovelchemotherapeutictarget:A.M.Gurnett,etal.;J.Biol.Chem.277,15913(2002)
- ToxoplasmagondiicyclicGMP-dependentkinase:chemotherapeutictargetingofanessentialparasiteproteinkinase:R.G.Donald,etal.;Eukaryot.Cell1,317(2002)
- AroleforcoccidiancGMP-dependentproteinkinaseinmotilityandinvasion:H.I.Wiersma,etal.;Int.J.Parasitol.34,369(2004)
- CharacterizationofPlasmodiumfalciparumcGMP-dependentproteinkinase(PfPKG):antiparasiticactivityofaPKGinhibitor:C.A.Diaz,etal.;Mol.Biochem.Parasitol.146,78(2006)
- Anticoccidialkinaseinhibitors:identificationofproteinkinasetargetssecondarytocGMP-dependentproteinkinase:R.G.Donald,etal.;Mol.Biochem.Parasitol.149,86(2006)
品牌介绍
Adipogen公司由三个子公司组成，分别是Adipogen,Inc.(韩国),AdipogenSA(瑞士)和 AdipogenCorporation(美国圣地亚哥)。总部设在美国，运营总部在瑞士利斯塔尔。Adipogen公司专门从事生命科学研究试剂的开发，如癌症、免疫、炎症、代谢疾病（糖尿病、肥胖）、干细胞和神经退行性疾病等领域。其重点关注开发创新优质的ELISA试剂盒。另外，也可提供抗体和蛋白产品，Adipogen拥有自己的化学实验室，致力于开发创新型小分子化合物。
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